Detalhe da pesquisa
1.
Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Blood
; 142(3): 260-273, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37192303
2.
TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice.
Blood
; 121(1): 85-94, 2013 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23144170
3.
T cell independent antibody responses with class switch and memory using peptides anchored on liposomes.
NPJ Vaccines
; 9(1): 115, 2024 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38909055
4.
An effector-reduced anti-ß-amyloid (Aß) antibody with unique aß binding properties promotes neuroprotection and glial engulfment of Aß.
J Neurosci
; 32(28): 9677-89, 2012 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787053
5.
Discovery and structure activity relationship of small molecule inhibitors of toxic ß-amyloid-42 fibril formation.
J Biol Chem
; 287(41): 34786-800, 2012 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891248
6.
Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases.
J Biol Chem
; 286(16): 13966-76, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21343310
7.
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Sci Transl Med
; 13(593)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980574
8.
Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression.
Sci Rep
; 8(1): 16725, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425303
9.
Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope.
J Alzheimers Dis
; 56(2): 585-599, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28035925
10.
Structure of Crenezumab Complex with Aß Shows Loss of ß-Hairpin.
Sci Rep
; 6: 39374, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27996029
11.
An Anti-ß-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.
PLoS One
; 11(3): e0152471, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27023444
12.
Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
Cell Rep
; 16(6): 1690-1700, 2016 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475227
13.
Increased efflux of amyloid-ß peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis.
J Alzheimers Dis
; 38(4): 767-86, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072071
14.
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy.
PLoS One
; 8(8): e72301, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977276
15.
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
Blood
; 111(5): 2755-64, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18180376
16.
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.
Proc Natl Acad Sci U S A
; 104(23): 9810-5, 2007 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17517595
17.
Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival.
J Immunol
; 176(1): 165-72, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16365407
18.
Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants.
J Infect Dis
; 193(11): 1598-605, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16652290
19.
CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice.
Vaccine
; 21(19-20): 2492-9, 2003 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12744883
20.
Influence of complement C3 amount on IgG responses in early life: immunization with C3b-conjugated antigen increases murine neonatal antibody responses.
Vaccine
; 23(3): 329-35, 2004 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15530677