Detalhe da pesquisa
1.
Safety, Tolerability and Pharmacokinetics of Half-Life Extended Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Monoclonal Antibodies AZD7442 (Tixagevimab-Cilgavimab) in Healthy Adults.
J Infect Dis
; 227(10): 1153-1163, 2023 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36683419
2.
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome.
Mol Pharm
; 20(7): 3505-3518, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37283406
3.
Pharmacokinetics under the COVID-19 storm.
Br J Clin Pharmacol
; 89(1): 158-186, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33226664
4.
Safety, tolerability, and pharmacokinetics of half-life extended SARS-CoV-2-neutralizing monoclonal antibodies AZD7442 (tixagevimab/cilgavimab) in healthy Japanese adults.
J Infect Chemother
; 29(11): 1061-1067, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524201
5.
Food constituent- and herb-drug interactions in oncology: Influence of quantitative modelling on Drug labelling.
Br J Clin Pharmacol
; 87(10): 3988-4000, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733472
6.
Blood retinal barrier and ocular pharmacokinetics: Considerations for the development of oncology drugs.
Biopharm Drug Dispos
; 42(4): 128-136, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33759216
7.
A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates.
Drug Metab Dispos
; 48(11): 1231-1238, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32893186
8.
Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy.
Pharm Res
; 33(4): 1003-17, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26718955
9.
Special issue on applications of modeling and simulation in pharmaceutical drug development.
Biopharm Drug Dispos
; 42(4): 105-106, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33880803
10.
Dopamine D2 receptor occupancy as a predictor of catalepsy in rats: a pharmacokinetic-pharmacodynamic modeling approach.
Pharm Res
; 31(10): 2605-17, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24792824
11.
Population pharmacokinetic-pharmacodynamic modeling of haloperidol in patients with schizophrenia using positive and negative syndrome rating scale.
J Clin Psychopharmacol
; 33(6): 731-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24113674
12.
Modelling and simulation of placebo effect: application to drug development in schizophrenia.
J Pharmacokinet Pharmacodyn
; 40(3): 377-88, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23315146
13.
Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini-review on availability and limitations.
Fundam Clin Pharmacol
; : e12967, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37968879
14.
Evaluating the performance of machine-learning regression models for pharmacokinetic drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
; 12(1): 122-134, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382697
15.
Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats.
Pharm Res
; 29(7): 1932-48, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437487
16.
Harnessing Clinical Trial and Real-World Data Towards an Understanding of Sex Effects on Drug Pharmacokinetics, Pharmacodynamics and Efficacy.
Front Pharmacol
; 13: 874606, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35734405
17.
Development of and insights from systems pharmacology models of antibody-drug conjugates.
CPT Pharmacometrics Syst Pharmacol
; 11(8): 967-990, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35712824
18.
Comparing the applications of machine learning, PBPK, and population pharmacokinetic models in pharmacokinetic drug-drug interaction prediction.
CPT Pharmacometrics Syst Pharmacol
; 11(12): 1560-1568, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36176050
19.
Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS-CoV-2 Infection.
Clin Pharmacol Ther
; 112(6): 1207-1213, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35797235
20.
Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective.
Clin Pharmacol Ther
; 112(4): 770-781, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34862964