Reproducibility of African giant pouched rats detecting Mycobacterium tuberculosis.

BACKGROUND: African pouched rats sniffing sputum samples provided by local clinics have significantly increased tuberculosis case findings in Tanzania and Mozambique. The objective of this study was to determine the reproducibility of rat results. METHODS: Over an 18-month period 11,869 samples were examined by the rats. Intra-rater reliability was assessed through Yule's Q. Inter-rater reliability was assessed with Krippendorff's alpha. RESULTS: Intra-rater reliability was high, with a mean Yule's Q of 0.9. Inter-rater agreement was fair, with Krippendorf's alpha ranging from 0.15 to 0.45. Both Intra- and Inter-rater reliability was independent of the sex of the animals, but they were positively correlated with age. Both intra- and inter-rater agreement was lowest for samples designated as smear-negative by the clinics. CONCLUSION: Overall, the reproducibility of tuberculosis detection rat results was fair and diagnostic results were therefore independent of the rats used.

JEAB Research Over Time: Species Used, Experimental Designs, Statistical Analyses, and Sex of Subjects.

We examined the species used as subjects in every article published in the Journal of the Experimental Analysis of Behavior (JEAB) from 1958 through 2013. We also determined the sex of subjects in every article with human subjects (N = 524) and in an equal number of randomly selected articles with nonhuman subjects, as well as the general type of experimental designs used. Finally, the percentage of articles reporting an inferential statistic was determined at 5-year intervals. In all, 35,317 subjects were studied in 3,084 articles; pigeons ranked first and humans second in number used. Within-subject experimental designs were more popular than between-subjects designs regardless of whether human or nonhuman subjects were studied but were used in a higher percentage of articles with nonhumans (75.4 %) than in articles with humans (68.2 %). The percentage of articles reporting an inferential statistic has increased over time, and more than half of the articles published in 2005 and 2010 reported one. Researchers who publish in JEAB frequently depart from Skinner's preferred research strategy, but it is not clear whether such departures are harmful. Finally, the sex of subjects was not reported in a sizable percentage of articles with both human and nonhuman subjects. This is an unfortunate oversight.

Punishment-induced resurgence.

The phenomenon of extinction-induced resurgence is well established, but there is comparatively little experimental evidence for punishment-induced resurgence. Punishment-induced resurgence can by tested by contingent shocks following the alternative response. The purpose of Experiment 1 was to test whether low-intensity shocks, that do not decrease rate of reinforcement, result in resurgence. Four rats served as subjects. Rats were exposed to three sequential conditions: (a) variable-interval (VI) 30-s food delivery for a lever press (target response); (b) VI 30-s food delivery for a nose poke (alternative response) and extinction of the lever press; (c) VI 30-s reinforcement for a nose poke with superimposed VI 60-s shock delivery. In the final condition, shocks increased gradually from 0.1 to 0.5 mA. Experiment 2 evaluated whether an abrupt introduction of a high-intensity shock would result in resurgence. Three rats served as subjects and were exposed to three sequential conditions: (a) VI 30-s food delivery for a lever press; (b) VI 30-s food delivery for a nose poke and extinction of the lever press; (c) continued VI 30-s reinforcement for a nose poke with superimposed VI 60-s 0.6 mA shock delivery. Resurgence was observed in all subjects, including in situations in which rate of responding, but not rate of reinforcement, decreased. The present study provides additional evidence for punishment-induced resurgence, but future studies are warranted to determine the extent to which punishment can produce resurgence with or without decreases in rates of reinforcement.

Convergent and Discriminant Validity of the Verbal Behavior Milestones Assessment and Placement Program (VB-MAPP) and the Vineland Adaptive Behavior Scales (VABS).

Behavior analysts frequently use the Verbal Behavior Milestones Assessment and Placement Program (VB-MAPP) to assess the language and social skills of children with autism in everyday practice and in research. Despite the widespread use of the VB-MAPP, its psychometric characteristics have not been extensively investigated. To provide information about its convergent validity, we calculated correlations between scores earned by 235 children with autism on the VB-MAPP and the Vineland Adaptive Behavior Scale (VABS), a commonly used assessment with good reliability and validity. We obtained moderate or strong positive correlations between the VB-MAPP Milestones score and VABS Communication, Socialization, and Daily Living Skills subdomains. There was also a strong positive correlation between the VB-MAPP Milestones score and VABS overall raw score. These findings suggest that the VB-MAPP Milestones Assessment measures aspects of social and communicative behavior comparable to those indexed by these VABS subdomains which, like prior findings, supports the use of the Milestones Assessment. No significant relationship was observed between the VB-MAPP Barriers score and the VABS Internalizing, Externalizing, or overall Maladaptive Behavior scores. These findings, like prior findings, question the value of the VB-MAPP's Barriers Assessment as a measure of maladaptive behavior.

Young adults with intellectual and other developmental disabilities acquire vocational skills with video prompting.

Students with intellectual and other developmental disabilities often require substantial support to acquire the skills needed to secure work experience and paid employment. Prior findings suggest that video prompting is likely to be an effective and feasible strategy for establishing such skills. To evaluate this possibility in a special education transition program, we examined the effectiveness of a video prompting procedure in teaching 8 young adults with developmental disabilities to perform job-related tasks (doing laundry, checking in to work, vacuuming, stripping bed). The intervention was effective with all participants. The skills maintained over 3 months, and the participants performed the tasks accurately in a new setting with different materials. Participants were reportedly satisfied with the intervention and deemed it easy to use.

Interobserver agreement and procedural fidelity: An odd asymmetry.

We examined articles with experiments published in the Journal of Applied Behavior Analysis and in Behavior Analysis in Practice from 2017 through 2021 to determine how frequently procedural fidelity was assessed. When procedural fidelity was assessed, we determined how often a measure of interobserver agreement for those fidelity data was provided. We also determined how often a measure of interobserver agreement for participants' behavior was provided. Across both journals and all years, 54.7% of relevant articles provided a measure of procedural fidelity. Of them, 17.7% provided a measure of interobserver agreement for procedural fidelity. In marked contrast, 96.4% provided interobserver agreement data for participants' behavior. It is unfortunate that applied behavior analysts frequently fail to provide procedural fidelity data and, when they do, often fail to provide interobserver agreement data for the fidelity data. Reviewers for, and editors of, behavior-analytic journals are encouraged to strongly consider the relative value of procedural fidelity and agreement on procedural fidelity measures when rendering recommendations on the suitability of a given submission.

Functional analyses of undesirable behavior by nonhumans: A concise review.

We reviewed 13 articles that used functional analysis in the assessment of undesirable behavior emitted by dogs, cats, a baboon, a lemur, a chimpanzee, and a vulture. The functional analysis produced a clear outcome for 32 of 33 subjects, demonstrating its efficacy with nonhumans. We propose several avenues for further examination of its application to nonhumans.

Increasing Physical Activity in Young Adults with an Intellectual Disability via a Classroom-wide Treatment Package.

The World Health Organization estimates that only 25% of adults meet the current recommendations for weekly exercise. Adults with an intellectual disability are less likely to meet these standards than other people. In the present study, a classroom-wide treatment package that arranged individualized daily choice (between dancing and strength training), modeling (live, followed by video), and token reinforcement, was used to: (a) increase the number of steps taken and calories burned by six participants, two from each of three classrooms, and (b) increase the percentage of students in those classrooms who were consistently engaged in exercise during designated sessions. All six participants took more steps and burned more calories during both phases of the intervention (live and video model) than during baseline. The percentage of students who were consistently engaged in exercise also increased during both phases of the intervention, compared to baseline, across all three classrooms. Limited maintenance data indicated that the increased step counts and calories burned sustained when school staff implemented the video model intervention without researcher involvement. Because the procedure we used was relatively easy to implement and produced promising results, it appears to merit further investigation.

Resurgence increases with repetition.

Resurgence refers to a behavioral process in which a recent response is extinguished (or reinforcement conditions worsen) and a previously extinguished response recurs. In previous research, resurgence has been reliably produced when the resurgence procedure is repeated. Changes in the degree of increase of the resurging response across iterations of the procedure have been inconsistent, however, with some studies showing increases and some showing no changes or decreases in resurgence magnitude. The present study examined the nature of resurgence across repeated iterations of the conventional resurgence procedure by exposing four pigeons to the resurgence procedure six times in succession. In the first condition of the resurgence procedure, pecks on one key (e.g., the left) were reinforced under a variable-interval (VI) 30-s schedule. In the second condition pecks on that key were extinguished, and pecks on another key (e.g., the right) were reinforced under the same schedule. In the final condition there were no programmed consequences for either response. Resurgence was observed in 21 of 24 opportunities (87.5%). Iteration-over-iteration increases in resurgence were observed in 15 of 20 opportunities (75.0%), and this increase was found to be statistically significant. These findings demonstrate that, under certain conditions, resurgence generally increases in magnitude with repeated exposure to the procedures that generate it.

Women in Behavior Analysis: A Review of the Literature.

Women have played, and continue to play, an important role in behavior analysis. Their participation as authors of journal articles and as journal editors was first quantified in 1983 and has been the topic of several subsequent articles. Other articles have addressed other aspects of women's participation in the discipline, but no review of articles concerned with women in behavior analysis has appeared. The present review (a) describes articles that quantified the participation of women, (b) presents a novel data set providing an updated overview of women's participation in eight behavior-analytic journals, (c) reviews suggestions from prominent female behavior analysts, (d) discusses other topics that pertain to the participation of women, (e) presents data describing the gender of authors who have written about women in behavior analysis, and (f) makes suggestions for future research. Women's participation in behavior analysis has increased greatly over the past half-century. The articles we review clearly document that increase and may have contributed to it, although that contribution is speculative.

Six Useful Websites for Practitioners Working in Schools.

A substantial, and seemingly increasing, number of Board Certified Behavior Analysts work in pre-K-12 schools. Many of them will be unfamiliar with the roles and activities of other school professionals, as well as with the structure, function, and mandates of schools. This article introduces 6 websites that are devoted to education. Accessing these free and user-friendly sites can provide practitioners with information and training activities that will help them function comfortably and competently in schools and benefit their clients to a greater extent. Our purpose in writing this article is to introduce and recommend these websites.

Citations of Murray Sidman's work in JEAB: Evidence of a long and large contribution.

We examined citations of Murray Sidman's publications in the Journal of the Experimental Analysis of Behavior from the journal's inception in 1958 through May 2020. On average, he was cited 35.6 times per year. The rate of citation did not change substantially across time and the cumulative citation count was 2,212. His 10 publications cited most often deal with behavior-analytic research methods, stimulus equivalence, and unsignaled free-operant (or Sidman) avoidance. Our data provide clear evidence of the breadth and depth of Sidman's influence on the experimental analysis of behavior across 7 decades. His contributions were both exceptional and praiseworthy and his legacy will long endure.

Looking to the future: will behavior analysis survive and prosper?

Behavior analysis as a discipline currently is doing relatively well. How it will do in the future is unclear and depends on how the field, and the world at large, changes. Five current characteristics of the discipline that appear to reduce the probability that it will survive and prosper are discussed and suggestions for improvement are offered. The areas of concern are (a) the small size and limited power of the discipline, (b) the growing focus of applied behavior analysis on autism spectrum disorders and little else, (c) the esoteric nature of much basic research, (d) the proliferation of "applied" research that really isn't applied, and (e) the widespread use of imprecise and potentially harmful technical language.

Motivating Operations and Negative Reinforcement.

The motivating operations concept has improved the precision of our approach to analyzing behavior; it serves as a framework for classifying events that alter the reinforcing and punishing effectiveness of other events. Nevertheless, some aspects of the concept are seriously flawed, thereby limiting its utility. We contend in this article that the emphasis it places on the onset of some stimuli (putative motivating operations) making their offset a reinforcer in the absence of a learning history (i.e., in the case of unconditioned motivating operations), or because of such a history (i.e., in the case of reflexive conditioned motivating operations), is of no value in predicting or controlling behavior. It is unfortunate that this pseudo-analysis has been widely accepted, which has drawn attention away from actual motivating operations that are relevant to negative reinforcement, and led to conceptually flawed explanations of challenging human behaviors that are escape-maintained. When used appropriately, the motivating operations concept can help to clarify the conditions under which a stimulus change (in particular, stimulus termination) will function as a negative reinforcer. From both a theoretical and a practical perspective, rethinking the application of the motivating operations concept to negative reinforcement is advantageous. Herein, we explore the implications of doing so with the aim of encouraging relevant research and improving the practice of applied behavior analysis.

Commit Heresy: Stop Using "Contingency".

The term "contingency" has long been widely used by behavior analysts, but their uses of the term are inconsistent with the vernacular definition of the term. Moreover, the term is not consistently defined by behavior analysts, but is instead used to refer to a variety of relations between and among stimuli and responses. In the interest of reducing jargon and potential confusion, we argue that behavior analysts should stop using "contingency" and related terms.

Motivating Operations and Discriminative Stimuli: Distinguishable but Interactive Variables.

The motivating operations concept has been of considerable interest and practical value to behavior analysts, including practitioners. Nonetheless, the concept has generated substantial controversy and has significant limitations. To address some of these limitations, we suggest that it would be wise to redefine motivating operations, to deemphasize the importance that has historically been placed on subtypes of conditioned motivating operations, to emphasize how motivating operations and discriminative stimuli interact, and to further examine the kinds of environmental changes that alter the reinforcing value of particular kinds of stimuli. These suggestions are detailed elsewhere and summarized in this article.

Participants in Behavior-Analytic Sports Studies: Can Anybody Play?

Participating in athletics confers a wide range of benefits, regardless of participants' gender or disability status. Our review of 95 behavior-analytic sports-performance articles revealed that over half of them included at least 1 female participant, but only 5 included at least 1 participant with a reported developmental disability. Given that females are often underrepresented as research participants, and that female athletes face unique barriers, it is heartening that so many articles involved female participants. Moreover, there were more female than male participants overall. However, it is surprising and distressing that so few articles involved participants with a developmental disability. Participating in sports can be a lifelong source of fitness, friends, and fun. Practitioners should encourage people of all ages, races, and genders, and from all disability categories, to find a sport they like, to learn to do it well enough to enjoy it, and to do it regularly. Researchers should give them the tools necessary to make those efforts as easy, and as fruitful, as possible. Nothing but good can come from these efforts.

Rapidly training African giant pouched rats (Cricetomys ansorgei) with multiple targets for scent detection.

Since 1997, APOPO, a non-profit organization based in Tanzania, has deployed African giant pouched rats (Cricetomys ansorgei) to detect landmines in post-conflict areas. More recent research suggests the pouched rats can also be trained to detect tuberculosis in human sputum samples. Despite proven success on both tasks, the potential impact of each rat is limited by the required training time and constraint to a single target odor. The aim of this project was to establish a technique to rapidly train pouched rats to detect multiple odor targets. Eight pouched rats were trained to detect five unrelated target odors in Experiment 1. In addition to training duration, we measured maintenance of all odor targets. In Experiment 2, we examined response persistence under conditions of extinction. Experiment 3 investigated whether refresher sessions before tests would maintain detection accuracy. The animals mastered all odor targets in significantly fewer sessions than APOPO's operational rats require to master a single target odor. Importantly, rats demonstrated strong discrimination between targets and non-targets despite the potential for interference and forgetting, suggesting pouched rats can be trained to detect at least five targets simultaneously. These results have the potential to increase the impact of each detection rat by both decreasing training time and expanding operational versatility, e.g., a single rat could be trained to detect multiple diseases.