Detalhe da pesquisa
1.
Low pKa of Lys promotes glycation at one complementarity-determining region of a bispecific antibody.
Biophys J
; 121(6): 1081-1093, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122736
2.
Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.
Allergy
; 75(5): 1188-1204, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838750
3.
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.
J Infect Dis
; 218(suppl_5): S612-S626, 2018 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29860496
4.
Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes.
Angiogenesis
; 19(3): 389-406, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27234973
5.
Interference in a Neutralizing Antibody Assay for Odronextamab, a CD20xCD3 Bispecific mAb, from Prior Rituximab Therapy and Possible Mitigation Strategy.
AAPS J
; 24(4): 76, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35725847
6.
Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054.
Cancer Immunol Res
; 10(10): 1190-1209, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895745
7.
CD22-targeted CD28 bispecific antibody enhances antitumor efficacy of odronextamab in refractory diffuse large B cell lymphoma models.
Sci Transl Med
; 14(670): eabn1082, 2022 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350988
8.
Differential Binding of Sarilumab and Tocilizumab to IL-6Rα and Effects of Receptor Occupancy on Clinical Parameters.
J Clin Pharmacol
; 61(5): 714-724, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314148
9.
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models.
Clin Cancer Res
; 26(6): 1408-1419, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848185
10.
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies.
Sci Transl Med
; 12(525)2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915305
11.
Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3-Knockin Mice.
Mol Cancer Ther
; 18(11): 2051-2062, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395688
12.
A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.
Sci Transl Med
; 11(497)2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217340
13.
A novel bispecific antibody platform to direct complement activity for efficient lysis of target cells.
Sci Rep
; 9(1): 12031, 2019 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31427700
14.
Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides.
Antimicrob Agents Chemother
; 52(6): 2120-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18391029
15.
Deconvolution of the cellular oxidative stress response with organelle-specific Peptide conjugates.
Chem Biol
; 14(8): 923-30, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17719491
16.
Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers.
Mol Cancer Ther
; 16(7): 1299-1311, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377489
17.
Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice.
Mol Cancer Ther
; 16(5): 861-870, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265006
18.
Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile.
Biochim Biophys Acta
; 1751(2): 213-6, 2005 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15963773
19.
Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice.
Skelet Muscle
; 5: 34, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26457176
20.
ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models.
Mol Cancer Ther
; 13(5): 1345-55, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24634416