Detalhe da pesquisa
1.
Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care.
Br J Cancer
; 130(6): 961-969, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272963
2.
Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients.
Br J Cancer
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38532102
3.
A Minimal PBPK Model for Plasma and Cerebrospinal Fluid Pharmacokinetics of Trastuzumab after Intracerebroventricular Administration in Patients with HER2-Positive Brain Metastatic Localizations.
Pharm Res
; 40(11): 2687-2697, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821769
4.
Paclitaxel with or without pazopanib for ovarian cancer relapsing during bevacizumab maintenance therapy: The GINECO randomized phase II TAPAZ study.
Gynecol Oncol
; 166(3): 389-396, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902297
5.
Plasma vemurafenib exposure and pre-treatment hepatocyte growth factor level are two factors contributing to the early peripheral lymphocytes depletion in BRAF-mutated melanoma patients.
Pharmacol Res
; 113(Pt A): 709-718, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378568
6.
Pazopanib pharmacokinetically guided dose optimization in three cancer patients with gastrointestinal resection.
Cancer Chemother Pharmacol
; 93(2): 169-175, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37620675
7.
Improving olaparib exposure to optimize adverse effects management.
Ther Adv Med Oncol
; 16: 17588359241248328, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665845
8.
Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab.
Pharmaceutics
; 15(8)2023 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37631343
9.
LC-MS/MS method for simultaneous quantification of osilodrostat and metyrapone in human plasma from patients treated for Cushing's Syndrome.
J Pharm Biomed Anal
; 228: 115316, 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868030
10.
Pharmacokinetics/Pharmacodynamics of Dabrafenib and Trametinib for Redifferentiation and Treatment of Radioactive Iodine-Resistant Mutated Advanced Differentiated Thyroid Cancer.
Thyroid
; 33(11): 1327-1338, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725566
11.
Clinical results of the EVESOR trial, a multiparameter phase I trial of everolimus and sorafenib combination in solid tumors.
Cancer Chemother Pharmacol
; 91(5): 361-373, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840749
12.
A PK-PD model linking biomarker dynamics to progression-free survival in patients treated with everolimus and sorafenib combination therapy, EVESOR phase I trial.
Cancer Chemother Pharmacol
; 91(5): 413-425, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37010549
13.
Massive tramadol ingestion resulting in fatal brain injury - a pharmacokinetic study with discussion on the involved mechanisms of toxicity.
Clin Toxicol (Phila)
; 60(9): 1059-1062, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35506822
14.
Monitoring of Dabrafenib and Trametinib in Serum and Self-Sampled Capillary Blood in Patients with BRAFV600-Mutant Melanoma.
Cancers (Basel)
; 14(19)2022 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230489
15.
Exposure-Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer.
Pharmaceutics
; 14(9)2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36145591
16.
Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Results from a Retrospective Multicenter Study.
Pharmaceuticals (Basel)
; 14(8)2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34451901
17.
Model-Based Quantification of Impact of Genetic Polymorphisms and Co-Medications on Pharmacokinetics of Tamoxifen and Six Metabolites in Breast Cancer.
Clin Pharmacol Ther
; 109(5): 1244-1255, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33047329
18.
Population Pharmacokinetics/Pharmacodynamics of Dabrafenib Plus Trametinib in Patients with BRAF-Mutated Metastatic Melanoma.
Cancers (Basel)
; 12(4)2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283865
19.
Evaluation of the Interaction of Amino Acid Infusion on 177Lu-Dotatate Pharmacokinetics in Patients with Gastroenteropancreatic Neuroendocrine Tumors.
Clin Pharmacokinet
; 58(2): 213-222, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29736841
20.
Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib.
Clin Pharmacokinet
; 58(4): 451-467, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30094711