Detalhe da pesquisa
1.
A multispecies framework for modeling adaptive immunity and immunotherapy in cancer.
PLoS Comput Biol
; 19(4): e1010976, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37083574
2.
Spastin mutations impair coordination between lipid droplet dispersion and reticulum.
PLoS Genet
; 16(4): e1008665, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315314
3.
Embracing Project Optimus: Can we Leverage Evolutionary Theory to Optimize Dosing in Oncology?
Pharm Res
; 39(12): 3259-3265, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36056271
4.
In Translation: FcRn across the Therapeutic Spectrum.
Int J Mol Sci
; 22(6)2021 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33802650
5.
Ratiometric Imaging Using a Single Dye Enables Simultaneous Visualization of Rac1 and Cdc42 Activation.
J Am Chem Soc
; 138(8): 2571-5, 2016 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26863024
6.
Optimizing Clinical Translation of Bispecific T-cell Engagers through Context Unification with a Quantitative Systems Pharmacology Model.
Clin Pharmacol Ther
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751031
7.
Therapeutic potential of procathepsin L-inhibiting and progesterone-entrapping dimethyl-ß-cyclodextrin nanoparticles in treating experimental sepsis.
Front Immunol
; 15: 1368448, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38550581
8.
Virtual clinical trials: A tool for predicting patients who may benefit from treatment beyond progression with pembrolizumab in non-small cell lung cancer.
CPT Pharmacometrics Syst Pharmacol
; 12(2): 236-249, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36547213
9.
Dissecting sources of variability in patient response to targeted therapy: anti-HER2 therapies as a case study.
Eur J Pharm Sci
; 186: 106467, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196833
10.
Development of bispecific T cell engagers: harnessing quantitative systems pharmacology.
Trends Pharmacol Sci
; 44(12): 880-890, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37852906
11.
Incorporating lesion-to-lesion heterogeneity into early oncology decision making.
Front Immunol
; 14: 1173546, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350966
12.
Population dynamics of immunological synapse formation induced by bispecific T cell engagers predict clinical pharmacodynamics and treatment resistance.
Elife
; 122023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490053
13.
Cellular kinetics: A clinical and computational review of CAR-T cell pharmacology.
Adv Drug Deliv Rev
; 188: 114421, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809868
14.
Speed and Location Both Matter: Antigen Stimulus Dynamics Controls CAR-T Cell Response.
Front Immunol
; 12: 748768, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34691062
15.
EdgeProps: A Computational Platform for Correlative Analysis of Cell Dynamics and Near-Edge Protein Activity.
Methods Mol Biol
; 1821: 47-56, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30062404