Detalhe da pesquisa
1.
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis
; 27(11-12): 913-928, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943677
2.
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia.
Cancer Res
; 84(7): 1084-1100, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266099
3.
Acquired resistance to venetoclax plus azacitidine in acute myeloid leukemia: In vitro models and mechanisms.
Biochem Pharmacol
; 216: 115759, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37604291
4.
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Cells
; 11(17)2022 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36078163
5.
Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia.
Biochem Pharmacol
; 205: 115283, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36208684
6.
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Blood Cancer J
; 11(6): 111, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099621
7.
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Clin Cancer Res
; 25(22): 6815-6826, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320594
8.
Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling.
Sci Rep
; 7(1): 8402, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827748