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Yi Chuan ; 33(6): 636-47, 2011 Jun.
Artigo em Zh | MEDLINE | ID: mdl-21684870

RESUMO

For research on genetic characters and evolutionary origin of the genome of baculoviruses, a comprehensive homology search and phylogenetic analysis of the complete genomes of Bombyx mori NPV and Bombyx mori were used. Three horizontally transferred genes (inhibitor of apoptosis, chitinase, and UDP-glucosyltransferase) were identified, and there was evidence that all of these genes were derived from the insect host. The results of analysis showed lots of differences between the features of horizontal transferred genes and the ones of whole genomic genes, such as nucleotide composition, codon usagebias and selection pressure. These results reconfirmed that the horizontally transferred genes are exogenous. The analysis of gene function suggested that horizontally transferred genes acquired from an ancestral host insect can increase the efficiency of baculoviruses transmission.


Assuntos
Bombyx/virologia , Transferência Genética Horizontal , Genômica/métodos , Nucleopoliedrovírus/genética , Animais , Evolução Molecular , Genes Virais/genética , Filogenia , Seleção Genética , Software
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