Detalhe da pesquisa
1.
Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes.
J Lipid Res
; 61(6): 870-883, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32156718
2.
Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
J Am Chem Soc
; 142(9): 4445-4455, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064871
3.
Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism.
Proc Natl Acad Sci U S A
; 113(41): E6064-E6071, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681620
4.
Molecular cartography of the human skin surface in 3D.
Proc Natl Acad Sci U S A
; 112(17): E2120-9, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825778
5.
Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system.
Protein Expr Purif
; 117: 44-51, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26405011
6.
Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.
J Bacteriol
; 198(4): 731-41, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668262
7.
Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate.
Org Biomol Chem
; 13(37): 9585-92, 2015 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26256511
8.
Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.
J Am Chem Soc
; 135(30): 11232-8, 2013 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23866020
9.
Molecular networking as a dereplication strategy.
J Nat Prod
; 76(9): 1686-99, 2013 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24025162
10.
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
J Am Chem Soc
; 134(17): 7359-66, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22480290
11.
Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations.
Anal Chem
; 84(21): 9259-67, 2012 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23009651
12.
Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.
J Am Chem Soc
; 133(37): 14492-5, 2011 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21823639
13.
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Proc Natl Acad Sci U S A
; 105(44): 17133-8, 2008 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18955706
14.
A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments.
ACS Chem Biol
; 14(4): 725-734, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30908011
15.
Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry.
PLoS One
; 14(2): e0211803, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735516
16.
Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis.
mSphere
; 3(5)2018 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30381354
17.
Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.
ACS Infect Dis
; 4(3): 391-402, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29243909
18.
Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
J Med Chem
; 61(8): 3325-3349, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29551072
19.
Assessing Antibiotic Permeability of Gram-Negative Bacteria via Nanofluidics.
ACS Nano
; 11(7): 6959-6967, 2017 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28605582
20.
LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates.
mSphere
; 2(4)2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28815210