Pesquisa | BVS Violência e Saúde

1.

A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates.

He, Peng; Lim, Kyungtae; Sun, Dawei; Pett, Jan Patrick; Jeng, Quitz; Polanski, Krzysztof; Dong, Ziqi; Bolt, Liam; Richardson, Laura; Mamanova, Lira; Dabrowska, Monika; Wilbrey-Clark, Anna; Madissoon, Elo; Tuong, Zewen Kelvin; Dann, Emma; Suo, Chenqu; Goh, Isaac; Yoshida, Masahiro; Nikolic, Marko Z; Janes, Sam M; He, Xiaoling; Barker, Roger A; Teichmann, Sarah A; Marioni, John C; Meyer, Kerstin B; Rawlins, Emma L.

Cell ; 185(25): 4841-4860.e25, 2022 Dec 08.

Artigo em Inglês | MEDLINE | ID: mdl-36493756

2.

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling.

Sun, Dawei; Llora Batlle, Oriol; van den Ameele, Jelle; Thomas, John C; He, Peng; Lim, Kyungtae; Tang, Walfred; Xu, Chufan; Meyer, Kerstin B; Teichmann, Sarah A; Marioni, John C; Jackson, Stephen P; Brand, Andrea H; Rawlins, Emma L.

EMBO J ; 41(21): e111338, 2022 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-36121125

3.

RTK signalling promotes epithelial columnar cell shape and apical junction maintenance in human lung progenitor cells.

Liu, Shuyu; Sun, Dawei; Butler, Richard; Rawlins, Emma L.

Development ; 150(11)2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-37260147

4.

Exploring the challenges and opportunities of public engagement with fundamental biology.

Clements-Brod, Naomi; Holmes, Leah; Rawlins, Emma L.

Development ; 149(18)2022 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-36106564

5.

In vitro platform to model the function of ionocytes in the human airway epithelium.

Vilà-González, Marta; Pinte, Laetitia; Fradique, Ricardo; Causa, Erika; Kool, Heleen; Rodrat, Mayuree; Morell, Carola Maria; Al-Thani, Maha; Porter, Linsey; Guo, Wenrui; Maeshima, Ruhina; Hart, Stephen L; McCaughan, Frank; Granata, Alessandra; Sheppard, David N; Floto, R Andres; Rawlins, Emma L; Cicuta, Pietro; Vallier, Ludovic.

Respir Res ; 25(1): 180, 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38664797

6.

Human lung development: recent progress and new challenges.

Nikolic, Marko Z; Sun, Dawei; Rawlins, Emma L.

Development ; 145(16)2018 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-30111617

7.

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

Hoyler, Thomas; Klose, Christoph S N; Souabni, Abdallah; Turqueti-Neves, Adriana; Pfeifer, Dietmar; Rawlins, Emma L; Voehringer, David; Busslinger, Meinrad; Diefenbach, Andreas.

Immunity ; 37(4): 634-48, 2012 Oct 19.

Artigo em Inglês | MEDLINE | ID: mdl-23063333

8.

FGFR2 is required for airway basal cell self-renewal and terminal differentiation.

Balasooriya, Gayan I; Goschorska, Maja; Piddini, Eugenia; Rawlins, Emma L.

Development ; 144(9): 1600-1606, 2017 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-28348168

9.

A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System.

Ma, Dan; Wang, Bowei; Zawadzka, Malgorzata; Gonzalez, Ginez; Wu, Zhaozong; Yu, Bin; Rawlins, Emma L; Franklin, Robin J M; Zhao, Chao.

J Neurosci ; 38(43): 9228-9239, 2018 10 24.

Artigo em Inglês | MEDLINE | ID: mdl-30228229

10.

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease.

Schiller, Herbert B; Montoro, Daniel T; Simon, Lukas M; Rawlins, Emma L; Meyer, Kerstin B; Strunz, Maximilian; Vieira Braga, Felipe A; Timens, Wim; Koppelman, Gerard H; Budinger, G R Scott; Burgess, Janette K; Waghray, Avinash; van den Berge, Maarten; Theis, Fabian J; Regev, Aviv; Kaminski, Naftali; Rajagopal, Jayaraj; Teichmann, Sarah A; Misharin, Alexander V; Nawijn, Martijn C.

Am J Respir Cell Mol Biol ; 61(1): 31-41, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30995076

11.

Developmental mechanisms and adult stem cells for therapeutic lung regeneration.

Lee, Joo-Hyeon; Rawlins, Emma L.

Dev Biol ; 433(2): 166-176, 2018 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-29291971

12.

Inhibition of ß-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.

Rognoni, Emanuel; Gomez, Celine; Pisco, Angela Oliveira; Rawlins, Emma L; Simons, Ben D; Watt, Fiona M; Driskell, Ryan R.

Development ; 143(14): 2522-35, 2016 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-27287810

13.

Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate.

Laresgoiti, Usua; Nikolic, Marko Z; Rao, Chandrika; Brady, Jane L; Richardson, Rachel V; Batchen, Emma J; Chapman, Karen E; Rawlins, Emma L.

Development ; 143(20): 3686-3699, 2016 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-27578791

14.

Cancer: Tumours build their niche.

Huch, Meritxell; Rawlins, Emma L.

Nature ; 545(7654): 292-293, 2017 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-28489827

15.

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Correia, Lúcia L; Johnson, Jo-Anne; McErlean, Peter; Bauer, Julien; Farah, Hassan; Rassl, Doris M; Rintoul, Robert C; Sethi, Tariq; Lavender, Paul; Rawlins, Emma L; Littlewood, Trevor D; Evan, Gerard I; McCaughan, Frank M.

Am J Respir Crit Care Med ; 195(11): 1494-1508, 2017 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-28199128

16.

Stem cells: Emergency back-up for lung repair.

Rawlins, Emma L.

Nature ; 517(7536): 556-7, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25631438

17.

Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans.

Wen, Ming-Hsuan; Barbosa Triana, Hector; Butler, Richard; Hu, Hsiang-Wei; Dai, Yang-Hong; Lawrence, Nicola; Hong, Jun-Jie; Garrett, Nigel; Jones-Green, Rue; Rawlins, Emma L; Dong, Ziqi; Koziol, Magdalena J; Gurdon, J B.

Biol Open ; 13(3)2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-37982514

18.

Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease.

Lim, Kyungtae; Donovan, Alex P A; Tang, Walfred; Sun, Dawei; He, Peng; Pett, J Patrick; Teichmann, Sarah A; Marioni, John C; Meyer, Kerstin B; Brand, Andrea H; Rawlins, Emma L.

Cell Stem Cell ; 30(1): 20-37.e9, 2023 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-36493780

19.

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease.

Lim, Kyungtae; Rutherford, Eimear N; Sun, Dawei; Van den Boomen, Dick J H; Edgar, James R; Bang, Jae Hak; Matesic, Lydia E; Lee, Joo-Hyeon; Lehner, Paul J; Marciniak, Stefan J; Rawlins, Emma L; Dickens, Jennifer A.

bioRxiv ; 2023 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-37693487

20.

Early human lung immune cell development and its role in epithelial cell fate.

Barnes, Josephine L; Yoshida, Masahiro; He, Peng; Worlock, Kaylee B; Lindeboom, Rik G H; Suo, Chenqu; Pett, J Patrick; Wilbrey-Clark, Anna; Dann, Emma; Mamanova, Lira; Richardson, Laura; Polanski, Krzysztof; Pennycuick, Adam; Allen-Hyttinen, Jessica; Herczeg, Iván T; Arzili, Romina; Hynds, Robert E; Teixeira, Vitor H; Haniffa, Muzlifah; Lim, Kyungtae; Sun, Dawei; Rawlins, Emma L; Oliver, Amanda J; Lyons, Paul A; Marioni, John C; Ruhrberg, Christiana; Tuong, Zewen Kelvin; Clatworthy, Menna R; Reading, James L; Janes, Sam M; Teichmann, Sarah A; Meyer, Kerstin B; Nikolic, Marko Z.

Sci Immunol ; 8(90): eadf9988, 2023 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-38100545

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