Detalhe da pesquisa
1.
MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models.
Int J Mol Sci
; 22(17)2021 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34502076
2.
Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice.
Mol Ther
; 27(5): 999-1016, 2019 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30852139
3.
Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer.
Mol Ther
; 25(12): 2705-2714, 2017 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882451
4.
Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo.
Mol Ther
; 24(6): 1106-1116, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26983359
5.
Treatment of Liver Cancer by C/EBPA saRNA.
Adv Exp Med Biol
; 983: 189-194, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28639200
6.
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.
Hepatology
; 59(1): 216-27, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929703
7.
Exploiting human CD34+ stem cell-conditioned medium for tissue repair.
Mol Ther
; 22(1): 149-59, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23985698
8.
Cannabidiol's cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress.
J Cannabis Res
; 6(1): 22, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720356
9.
Enhancing SIRT1 Gene Expression Using Small Activating RNAs: A Novel Approach for Reversing Metabolic Syndrome.
Nucleic Acid Ther
; 32(6): 486-496, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895511
10.
Cannabinoids in the landscape of cancer.
J Cancer Res Clin Oncol
; 147(9): 2507-2534, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34259916
11.
Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer.
Clin Cancer Res
; 27(21): 5961-5978, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34407972
12.
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Mol Ther Nucleic Acids
; 19: 361-370, 2020 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31877412
13.
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Clin Cancer Res
; 26(15): 3936-3946, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32357963
14.
Targeted Delivery of C/EBPα-saRNA by RNA Aptamers Shows Anti-tumor Effects in a Mouse Model of Advanced PDAC.
Mol Ther Nucleic Acids
; 18: 142-154, 2019 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31546149
15.
Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma.
Oncogene
; 38(18): 3446-3457, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643190
16.
Aspirin and clopidogrel treatment impair nitric oxide biosynthesis by platelets.
J Mol Cell Cardiol
; 45(2): 223-9, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18606420
17.
Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.
Oncogene
; 37(24): 3216-3228, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29511346
18.
Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth.
Mol Ther Nucleic Acids
; 6: 80-88, 2017 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325302
19.
Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment.
Cardiovasc Res
; 59(1): 152-9, 2003 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829186
20.
A Short-activating RNA Oligonucleotide Targeting the Islet ß-cell Transcriptional Factor MafA in CD34(+) Cells.
Mol Ther Nucleic Acids
; 2: e97, 2013 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23736775