Pesquisa | BVS Violência e Saúde

1.

Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design.

Klesmith, Justin R; Wu, Lan; Lobb, Roy R; Rennert, Paul D; Hackel, Benjamin J.

Biochemistry ; 58(48): 4869-4881, 2019 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-31702909

2.

Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins.

Klesmith, Justin R; Su, Lihe; Wu, Lan; Schrack, Ian A; Dufort, Fay J; Birt, Alyssa; Ambrose, Christine; Hackel, Benjamin J; Lobb, Roy R; Rennert, Paul D.

Mol Pharm ; 16(8): 3544-3558, 2019 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-31242389

3.

TIM-family proteins inhibit HIV-1 release.

Li, Minghua; Ablan, Sherimay D; Miao, Chunhui; Zheng, Yi-Min; Fuller, Matthew S; Rennert, Paul D; Maury, Wendy; Johnson, Marc C; Freed, Eric O; Liu, Shan-Lu.

Proc Natl Acad Sci U S A ; 111(35): E3699-707, 2014 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-25136083

4.

Characterizing functional domains for TIM-mediated enveloped virus entry.

Moller-Tank, Sven; Albritton, Lorraine M; Rennert, Paul D; Maury, Wendy.

J Virol ; 88(12): 6702-13, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24696470

5.

Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry.

Moller-Tank, Sven; Kondratowicz, Andrew S; Davey, Robert A; Rennert, Paul D; Maury, Wendy.

J Virol ; 87(15): 8327-41, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23698310

6.

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.

Suzuki, Kazuhiro; Okuno, Tatsusada; Yamamoto, Midori; Pasterkamp, R Jeroen; Takegahara, Noriko; Takamatsu, Hyota; Kitao, Tomoe; Takagi, Junichi; Rennert, Paul D; Kolodkin, Alex L; Kumanogoh, Atsushi; Kikutani, Hitoshi.

Nature ; 446(7136): 680-4, 2007 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-17377534

7.

CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma.

Su, Lihe; Wu, Lan; Lobb, Roy R; Rennert, Paul D; Ambrose, Christine.

Oncoimmunology ; 11(1): 2111904, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35990518

8.

Identification of proteoglycans as the APRIL-specific binding partners.

Ingold, Karine; Zumsteg, Adrian; Tardivel, Aubry; Huard, Bertrand; Steiner, Quynh-Giao; Cachero, Teresa G; Qiang, Fang; Gorelik, Leonid; Kalled, Susan L; Acha-Orbea, Hans; Rennert, Paul D; Tschopp, Jürg; Schneider, Pascal.

J Exp Med ; 201(9): 1375-83, 2005 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-15851487

9.

Anti-CD19 CAR T Cells That Secrete a Biparatopic Anti-CLEC12A Bridging Protein Have Potent Activity Against Highly Aggressive Acute Myeloid Leukemia In Vitro and In Vivo.

Rennert, Paul D; Dufort, Fay J; Su, Lihe; Sanford, Tom; Birt, Alyssa; Wu, Lan; Lobb, Roy R; Ambrose, Christine.

Mol Cancer Ther ; 20(10): 2071-2081, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34253594

10.

Anti-CD19 CAR T cells potently redirected to kill solid tumor cells.

Ambrose, Christine; Su, Lihe; Wu, Lan; Dufort, Fay J; Sanford, Thomas; Birt, Alyssa; Hackel, Benjamin J; Hombach, Andreas; Abken, Hinrich; Lobb, Roy R; Rennert, Paul D.

PLoS One ; 16(3): e0247701, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33735268

11.

Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs.

Alcamo, Elizabeth; Hacohen, Nir; Schulte, Leah C; Rennert, Paul D; Hynes, Richard O; Baltimore, David.

J Exp Med ; 195(2): 233-44, 2002 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-11805150

12.

Bimodal regulation of T cell-mediated immune responses by TIM-4.

Mizui, Masayuki; Shikina, Takashi; Arase, Hisashi; Suzuki, Kazuhiro; Yasui, Teruhito; Rennert, Paul D; Kumanogoh, Atsushi; Kikutani, Hitoshi.

Int Immunol ; 20(5): 695-708, 2008 May.

Artigo em Inglês | MEDLINE | ID: mdl-18367551

13.

Combination cancer immunotherapy and new immunomodulatory targets.

Mahoney, Kathleen M; Rennert, Paul D; Freeman, Gordon J.

Nat Rev Drug Discov ; 14(8): 561-84, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26228759

14.

Novel roles for TIM-1 in immunity and infection.

Rennert, Paul D.

Immunol Lett ; 141(1): 28-35, 2011 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-21911007

15.

Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1).

Curtiss, Miranda L; Hostager, Bruce S; Stepniak, Elizabeth; Singh, Melody; Manhica, Natalie; Knisz, Judit; Traver, Geri; Rennert, Paul D; Colgan, John D; Rothman, Paul B.

Mol Immunol ; 48(12-13): 1424-31, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21513984

16.

Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.

Sonar, Sanchaita Sriwal; Hsu, Yen-Ming; Conrad, Melanie Lynn; Majeau, Gerard R; Kilic, Ayse; Garber, Ellen; Gao, Yan; Nwankwo, Chioma; Willer, Gundi; Dudda, Jan C; Kim, Hellen; Bailly, Véronique; Pagenstecher, Axel; Rennert, Paul D; Renz, Harald.

J Clin Invest ; 120(8): 2767-81, 2010 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-20628202

17.

Cutting edge: Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk.

Chang, Sun-Young; Cha, Hye-Ran; Igarashi, Osamu; Rennert, Paul D; Kissenpfennig, Adrien; Malissen, Bernard; Nanno, Masanobu; Kiyono, Hiroshi; Kweon, Mi-Na.

J Immunol ; 180(7): 4361-5, 2008 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-18354155

18.

Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia.

Jafri, Mubeen; Donnelly, Bryan; Allen, Steven; Bondoc, Alex; McNeal, Monica; Rennert, Paul D; Weinreb, Paul H; Ward, Richard; Tiao, Greg.

Am J Physiol Gastrointest Liver Physiol ; 295(1): G16-G26, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18436621

19.

Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals.

Binné, Lauri L; Scott, Martin L; Rennert, Paul D.

J Immunol ; 178(7): 4342-50, 2007 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-17371991

20.

Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses.

Sizing, Irene D; Bailly, Véronique; McCoon, Patricia; Chang, Wenjie; Rao, Sambasiva; Pablo, Lourdes; Rennard, Rachel; Walsh, Meghan; Li, Zhifang; Zafari, Mohammad; Dobles, Max; Tarilonte, Leticia; Miklasz, Steven; Majeau, Gerard; Godbout, Kevin; Scott, Martin L; Rennert, Paul D.

J Immunol ; 178(4): 2249-61, 2007 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-17277130

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