Detalhe da pesquisa
1.
Impact of Exposure to Diesel Exhaust on Inflammation Markers and Proteases in Former Smokers with Chronic Obstructive Pulmonary Disease: A Randomized, Double-blinded, Crossover Study.
Am J Respir Crit Care Med
; 205(9): 1046-1052, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35202552
2.
Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure.
Respir Res
; 23(1): 248, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114491
3.
Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study.
J Allergy Clin Immunol
; 147(5): 1671-1682, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069714
4.
Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting ß 2-Adrenoceptor Agonist Combination Therapy in Asthma.
Mol Pharmacol
; 99(3): 197-216, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33376135
5.
Particle Depletion Does Not Remediate Acute Effects of Traffic-related Air Pollution and Allergen. A Randomized, Double-Blind Crossover Study.
Am J Respir Crit Care Med
; 200(5): 565-574, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30974969
6.
Long-Acting ß2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.
Mol Pharmacol
; 94(3): 1031-1046, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29959223
7.
Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.
J Allergy Clin Immunol
; 138(6): 1690-1700, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27283384
8.
Induction of regulator of G-protein signaling 2 expression by long-acting ß2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells.
J Pharmacol Exp Ther
; 348(1): 12-24, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24163441
9.
ß2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids.
Proc Natl Acad Sci U S A
; 108(49): 19713-8, 2011 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22080612
10.
Inhibition of ABCC4 potentiates combination beta agonist and glucocorticoid responses in human airway epithelial cells.
J Allergy Clin Immunol
; 141(3): 1127-1130.e5, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103996
11.
Controlled human exposures to diesel exhaust or particle-depleted diesel exhaust with allergen modulates transcriptomic responses in the lung.
Sci Total Environ
; 945: 173688, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38851342
12.
Phosphodiesterase 4 inhibitors augment the ability of formoterol to enhance glucocorticoid-dependent gene transcription in human airway epithelial cells: a novel mechanism for the clinical efficacy of roflumilast in severe chronic obstructive pulmonary disease.
Mol Pharmacol
; 83(4): 894-906, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23389862
13.
Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta2-adrenoceptor agonists.
J Pharmacol Exp Ther
; 338(3): 860-9, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21622733
14.
Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells.
J Immunol
; 183(10): 6788-99, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19880449
15.
Glucocorticoids inhibit IL-1beta-induced GM-CSF expression at multiple levels: roles for the ERK pathway and repression by MKP-1.
Biochem J
; 427(1): 113-24, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20100175
16.
Concentration-dependent health effects of air pollution in controlled human exposures.
Environ Int
; 150: 106424, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596522
17.
Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression.
Epigenetics Chromatin
; 14(1): 54, 2021 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34895312
18.
Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
J Biol Chem
; 284(39): 26803-15, 2009 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19648110
19.
Regulation of tristetraprolin expression by interleukin-1 beta and dexamethasone in human pulmonary epithelial cells: roles for nuclear factor-kappa B and p38 mitogen-activated protein kinase.
J Pharmacol Exp Ther
; 330(2): 575-85, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19435930
20.
Air pollution and DNA methylation: effects of exposure in humans.
Clin Epigenetics
; 11(1): 131, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481107