Detalhe da pesquisa
1.
Selective inhibitors of the PSEN1-gamma-secretase complex.
J Biol Chem
; 299(6): 104794, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164155
2.
High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity.
J Lipid Res
; 51(12): 3559-67, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805092
3.
A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science
; 363(6431)2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30846569
4.
Association of SIRT1 gene variation with visceral obesity.
Hum Genet
; 124(4): 431-6, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18820948
5.
Variants in the FTO gene are associated with common obesity in the Belgian population.
Mol Genet Metab
; 93(4): 481-4, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18055244
6.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 11(2): 363-379, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057263
7.
IMI European Lead Factory - democratizing access to high-throughput screening.
Nat Rev Drug Discov
; 21(4): 245-246, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907316
8.
Design, synthesis, and tripeptidyl peptidase II inhibitory activity of a novel series of (S)-2,3-dihydro-2-(4-alkyl-1H-imidazol-2-yl)-1H-indoles.
J Med Chem
; 45(24): 5303-10, 2002 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12431057
9.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 13(2): 434-435, 2019 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31412287
10.
Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?
J Pharmacol Toxicol Methods
; 60(1): 1-10, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19439185
11.
Common variants in the gene for the serotonin receptor 6 (HTR6) do not contribute to obesity.
J Genet
; 89(4): 469-72, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21273698
12.
Tripeptidyl-peptidase II (TPP II) inhibitory activity of (S)-2,3-dihydro-2-(1H-imidazol-2-yl)-1H-indoles, a systematic SAR evaluation. Part 2.
Bioorg Med Chem Lett
; 13(24): 4467-71, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14643348