Pesquisa | BVS Violência e Saúde

1.

Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V.

Zhang, Xu; Nguyen, Khoa Dang; Rudnick, Paul A; Roper, Nitin; Kawaler, Emily; Maity, Tapan K; Awasthi, Shivangi; Gao, Shaojian; Biswas, Romi; Venugopalan, Abhilash; Cultraro, Constance M; Fenyö, David; Guha, Udayan.

Mol Cell Proteomics ; 18(4): 622-641, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30617155

2.

Industry Collaboration and Primary Guest Authorship of High-Impact Randomized Clinical Trials: A Cross-Sectional Study.

Roper, Nitin; Korenstein, Deborah.

J Gen Intern Med ; 30(10): 1421-5, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25832619

3.

Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib-resistant EGFR-driven Lung Cancer.

Roper, Nitin; El Meskini, Rajaa; Maity, Tapan; Atkinson, Devon; Day, Amanda; Pate, Nathan; Cultraro, Constance M; Pack, Svetlana; Zgonc, Valerie; Weaver Ohler, Zoe; Guha, Udayan.

Cancer Res Commun ; 4(2): 337-348, 2024 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-38276867

4.

Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells.

Pasterczyk, Katherine R; Li, Xiao Ling; Singh, Ragini; Zibitt, Meira S; Hartford, Corrine Corrina R; Pongor, Lorinc; Jenkins, Lisa M; Hu, Yue; Zhao, Patrick X; Muys, Bruna R; Kumar, Suresh; Roper, Nitin; Aladjem, Mirit I; Pommier, Yves; Grammatikakis, Ioannis; Lal, Ashish.

Mol Cell Biol ; 44(2): 43-56, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38347726

5.

Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts.

Arakawa, Yasuhiro; Jo, Ukhyun; Kumar, Suresh; Sun, Nai-Yun; Elloumi, Fathi; Thomas, Anish; Roper, Nitin; Varghese, Diana Grace; Takebe, Naoko; Zhang, Xiaohu; Ceribelli, Michele; Holland, David O; Beck, Erin; Itkin, Zina; McKnight, Crystal; Wilson, Kelli M; Travers, Jameson; Klumpp-Thomas, Carleen; Thomas, Craig J; Hoang, Chuong D; Hernandez, Jonathan M; Del Rivero, Jaydira; Pommier, Yves.

Cancer Res Commun ; 4(3): 834-848, 2024 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-38451783

6.

Conflicts of Interest.

Roper, Nitin.

N Engl J Med ; 373(8): 778, 2015 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-26287863

7.

Exploration of HER2 (ERBB2) immunohistochemistry in non-small cell lung cancer: correlation with ERBB2 mutational status: experimental research.

Cardillo, Anthony B; Kovar, Sierra; Roper, Nitin; Hicks, David G; Velez, Moises J.

Ann Med Surg (Lond) ; 85(6): 2640-2646, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37363568

8.

Preclinical Models of Adrenocortical Cancer.

Sedlack, Andrew J H; Hatfield, Samual J; Kumar, Suresh; Arakawa, Yasuhiro; Roper, Nitin; Sun, Nai-Yun; Nilubol, Naris; Kiseljak-Vassiliades, Katja; Hoang, Chuong D; Bergsland, Emily K; Hernandez, Jonathan M; Pommier, Yves; Del Rivero, Jaydira.

Cancers (Basel) ; 15(11)2023 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-37296836

9.

ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.

Schultz, Christopher W; Zhang, Yang; Elmeskini, Rajaa; Zimmermann, Astrid; Fu, Haiqing; Murai, Yasuhisa; Wangsa, Darawalee; Kumar, Suresh; Takahashi, Nobuyuki; Atkinson, Devon; Saha, Liton Kumar; Lee, Chien-Fei; Elenbaas, Brian; Desai, Parth; Sebastian, Robin; Sharma, Ajit Kumar; Abel, Melissa; Schroeder, Brett; Krishnamurthy, Manan; Kumar, Rajesh; Roper, Nitin; Aladjem, Mirit; Zenke, Frank T; Ohler, Zoe Weaver; Pommier, Yves; Thomas, Anish.

EMBO Mol Med ; 15(8): e17313, 2023 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-37491889

10.

Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex.

Sun, Yilun; Baechler, Simone A; Zhang, Xiaohu; Kumar, Suresh; Factor, Valentina M; Arakawa, Yasuhiro; Chau, Cindy H; Okamoto, Kanako; Parikh, Anup; Walker, Bob; Su, Yijun P; Chen, Jiji; Ting, Tabitha; Huang, Shar-Yin N; Beck, Erin; Itkin, Zina; McKnight, Crystal; Xie, Changqing; Roper, Nitin; Nijhawan, Deepak; Figg, William Douglas; Meltzer, Paul S; Yang, James C; Thomas, Craig J; Pommier, Yves.

Nat Commun ; 14(1): 3762, 2023 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-37353483

11.

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.

Pongor, Lorinc Sándor; Schultz, Christopher W; Rinaldi, Lorenzo; Wangsa, Darawalee; Redon, Christophe E; Takahashi, Nobuyuki; Fialkoff, Gavriel; Desai, Parth; Zhang, Yang; Burkett, Sandra; Hermoni, Nadav; Vilk, Noa; Gutin, Jenia; Gergely, Rona; Zhao, Yongmei; Nichols, Samantha; Vilimas, Rasa; Sciuto, Linda; Graham, Chante; Caravaca, Juan Manuel; Turan, Sevilay; Tsai-Wei, Shen; Rajapakse, Vinodh N; Kumar, Rajesh; Upadhyay, Deep; Kumar, Suresh; Kim, Yoo Sun; Roper, Nitin; Tran, Bao; Hewitt, Stephen M; Kleiner, David E; Aladjem, Mirit I; Friedman, Nir; Hager, Gordon L; Pommier, Yves; Ried, Thomas; Thomas, Anish.

Cancer Discov ; 13(4): 928-949, 2023 04 03.

Artigo em Inglês | MEDLINE | ID: mdl-36715552

12.

New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications.

Jhawar, Sakshi; Arakawa, Yasuhiro; Kumar, Suresh; Varghese, Diana; Kim, Yoo Sun; Roper, Nitin; Elloumi, Fathi; Pommier, Yves; Pacak, Karel; Del Rivero, Jaydira.

Cancers (Basel) ; 14(3)2022 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-35158861

13.

Preclinical Models of Neuroendocrine Neoplasia.

Sedlack, Andrew J H; Saleh-Anaraki, Kimia; Kumar, Suresh; Ear, Po Hien; Lines, Kate E; Roper, Nitin; Pacak, Karel; Bergsland, Emily; Quelle, Dawn E; Howe, James R; Pommier, Yves; Del Rivero, Jaydira.

Cancers (Basel) ; 14(22)2022 Nov 17.

Artigo em Inglês | MEDLINE | ID: mdl-36428741

14.

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models.

Lissa, Delphine; Takahashi, Nobuyuki; Desai, Parth; Manukyan, Irena; Schultz, Christopher W; Rajapakse, Vinodh; Velez, Moises J; Mulford, Deborah; Roper, Nitin; Nichols, Samantha; Vilimas, Rasa; Sciuto, Linda; Chen, Yuanbin; Guha, Udayan; Rajan, Arun; Atkinson, Devon; El Meskini, Rajaa; Weaver Ohler, Zoe; Thomas, Anish.

Nat Commun ; 13(1): 2023, 2022 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-35440132

15.

Parathyroid Carcinoma: Incidence, Survival Analysis, and Management: A Study from the SEER Database and Insights into Future Therapeutic Perspectives.

Ullah, Asad; Khan, Jaffar; Waheed, Abdul; Sharma, Nitasha; Pryor, Elizabeth K; Stumpe, Tanner R; Velasquez Zarate, Luis; Cason, Frederick D; Kumar, Suresh; Misra, Subhasis; Kavuri, Sravan; Mesa, Hector; Roper, Nitin; Foroutan, Shahin; Karki, Nabin Raj; Del Rivero, Jaydira; Simonds, William F; Karim, Nagla Abdel.

Cancers (Basel) ; 14(6)2022 Mar 10.

Artigo em Inglês | MEDLINE | ID: mdl-35326576

16.

Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.

Pongor, Lorinc S; Tlemsani, Camille; Elloumi, Fathi; Arakawa, Yasuhiro; Jo, Ukhyun; Gross, Jacob M; Mosavarpour, Sara; Varma, Sudhir; Kollipara, Rahul K; Roper, Nitin; Teicher, Beverly A; Aladjem, Mirit I; Reinhold, William; Thomas, Anish; Minna, John D; Johnson, Jane E; Pommier, Yves.

iScience ; 25(11): 105338, 2022 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-36325065

17.

Industry Collaboration and Primary Guest Authorship of High-Impact Clinical Trials.

Roper, Nitin; Korenstein, Deborah.

J Gen Intern Med ; 31(1): 12, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26014893

18.

The Immunotherapy Landscape in Adrenocortical Cancer.

Pegna, Guillaume J; Roper, Nitin; Kaplan, Rosandra N; Bergsland, Emily; Kiseljak-Vassiliades, Katja; Habra, Mouhammed Amir; Pommier, Yves; Del Rivero, Jaydira.

Cancers (Basel) ; 13(11)2021 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-34071333

19.

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer.

Roper, Nitin; Velez, Moises J; Chiappori, Alberto; Kim, Yoo Sun; Wei, Jun S; Sindiri, Sivasish; Takahashi, Nobuyuki; Mulford, Deborah; Kumar, Suresh; Ylaya, Kris; Trindade, Christopher; Manukyan, Irena; Brown, Anna-Leigh; Trepel, Jane B; Lee, Jung-Min; Hewitt, Stephen; Khan, Javed; Thomas, Anish.

Nat Commun ; 12(1): 3880, 2021 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-34162872

20.

Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma.

Kim, Chul; Xi, Liqiang; Cultraro, Constance M; Wei, Fang; Jones, Gregory; Cheng, Jordan; Shafiei, Ahmad; Pham, Trinh Hoc-Tran; Roper, Nitin; Akoth, Elizabeth; Ghafoor, Azam; Misra, Vikram; Monkash, Nina; Strom, Charles; Tu, Michael; Liao, Wei; Chia, David; Morris, Clive; Steinberg, Seth M; Bagheri, Hadi; Wong, David T W; Raffeld, Mark; Guha, Udayan.

Cancers (Basel) ; 13(13)2021 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-34283064

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