Detalhe da pesquisa
1.
Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.
Annu Rev Immunol
; 35: 229-253, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446063
2.
Modular design of synthetic receptors for programmed gene regulation in cell therapies.
Cell
; 185(8): 1431-1443.e16, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35427499
3.
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies.
Cell
; 181(3): 728-744.e21, 2020 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302591
4.
Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.
Cell
; 164(4): 770-9, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26830879
5.
Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.
Cell
; 164(4): 780-91, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26830878
6.
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.
Cell
; 167(2): 419-432.e16, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693353
7.
Naturally occurring T cell mutations enhance engineered T cell therapies.
Nature
; 626(7999): 626-634, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326614
8.
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.
Immunity
; 50(2): 477-492.e8, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737146
9.
Toward the clinical development of synthetic immunity to cancer.
Immunol Rev
; 320(1): 83-99, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491719
10.
The actin-driven spatiotemporal organization of T-cell signaling at the system scale.
Immunol Rev
; 256(1): 133-47, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24117818
11.
IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells.
J Immunol
; 192(12): 5687-94, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813204
12.
CD4+ CAR-T cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR-T cell therapy.
Blood Adv
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574299
13.
The CD3 zeta subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse.
J Immunol
; 186(12): 6839-47, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21543646
14.
Synthesizing a Smarter CAR T Cell: Advanced Engineering of T-cell Immunotherapies.
Cancer Immunol Res
; 11(8): 1030-1043, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37429007
15.
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors.
J Cell Biol
; 222(3)2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36520493
16.
Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma.
J Nucl Med
; 64(1): 137-144, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35981900
17.
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
bioRxiv
; 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37781607
18.
Mycobacterial shuttle vectors designed for high-level protein expression in infected macrophages.
Appl Environ Microbiol
; 78(19): 6829-37, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22820329
19.
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion.
J Exp Med
; 219(8)2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758909
20.
Multidimensional control of therapeutic human cell function with synthetic gene circuits.
Science
; 378(6625): 1227-1234, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36520914