RESUMO
INTRODUCTION: The genus Bartonella includes species and subspecies of fastidious, facultative intracellular Gram-negative bacilli that infect a wide variety of mammalian reservoirs including cats and humans. In 2022, the Ecuadorian Ministry of Health reported an outbreak of cat scratch disease caused by B. henselae in the city of Guayaquil. Therefore, we aimed to characterize the presence of Bartonella spp. in domestic and stray cats from the area of Guayaquil where the outbreak happened in 2022. METHODS: Whole blood samples of 100 domestic and stray cats were collected. Riboflavin synthase (ribC) and 16S rRNA genes detection was performed by PCR using Bartonella spp. specific primers, followed by Sanger sequencing and phylogenetic analysis. RESULTS: 14 cats were positive for Bartonella spp. carriage. Phylogenetic analysis confirmed the presence of 12 cats infected with B. henselae and 2 cats with B. clarridgeiae. CONCLUSIONS: There is a high prevalence of Bartonella spp. carriage in cats in the city of Guayaquil within the area where a recent cat scratch disease outbreak happened. Considering the high presence of cats and other domestic and stray animals in the city of Guayaquil, a One Health approach for surveillance and prevention of zoonotic diseases like cat scratch disease is needed.
Assuntos
Infecções por Bartonella , Bartonella henselae , Bartonella , Doenças do Gato , Doença da Arranhadura de Gato , Surtos de Doenças , Filogenia , RNA Ribossômico 16S , Animais , Gatos , Equador/epidemiologia , Surtos de Doenças/veterinária , Bartonella/genética , Bartonella/isolamento & purificação , Bartonella/classificação , Doença da Arranhadura de Gato/epidemiologia , Doença da Arranhadura de Gato/microbiologia , Doenças do Gato/microbiologia , Doenças do Gato/epidemiologia , Bartonella henselae/genética , Bartonella henselae/isolamento & purificação , RNA Ribossômico 16S/genética , Infecções por Bartonella/epidemiologia , Infecções por Bartonella/veterinária , Infecções por Bartonella/microbiologia , Portador Sadio/microbiologia , Portador Sadio/epidemiologia , Portador Sadio/veterinária , Masculino , Feminino , PrevalênciaRESUMO
We present cosmological constraints arising from the first measurement of the radial (line-of-sight) baryon acoustic oscillations (BAO) scale in the large scale structure traced by the galaxy distribution. Here we use these radial BAO measurements at z = 0.24 and z = 0.43 to derive new constraints on dark energy and its equation of state for a flat universe, without any other assumptions on the cosmological model: w = -1.14 + or - 0.39 (assumed constant), Omega(m) = 0.24(-0.05);(+0.06). If we drop the assumption of flatness and include previous cosmic microwave background and supernova data, we find w = -0.974 + or - 0.058, Omega(m) = 0.271 + or - 0.015, and Omega(k) = -0.002 + or - 0.006, in good agreement with a flat cold dark matter cosmology with a cosmological constant. To our knowledge, these are the most stringent constraints on these parameters to date under our stated assumptions.