Detalhe da pesquisa
1.
Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism.
Drug Metab Dispos
; 51(2): 183-192, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351835
2.
De novo PBX1 variant in a patient with glaucoma, kidney anomalies, and developmental delay: An expansion of the CAKUTHED phenotype.
Am J Med Genet A
; 188(3): 919-925, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34797033
3.
The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements.
J Biol Chem
; 295(26): 8725-8735, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376693
4.
The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
J Biol Chem
; 295(9): 2698-2712, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31988246
5.
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Biochem J
; 477(17): 3131-3145, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32766732
6.
Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.
Breast Cancer Res
; 22(1): 51, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32430040
7.
Pancreatic Cancer, A Mis-interpreter of the Epigenetic Language.
Yale J Biol Med
; 89(4): 575-590, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28018146
8.
Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen.
Pharmacogenet Genomics
; 25(4): 157-63, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25714002
9.
Comparative uterotrophic effects of endoxifen and tamoxifen in ovariectomized Sprague-Dawley rats.
Toxicol Pathol
; 42(8): 1188-96, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24670817
10.
UGT1A1 genotype-guided phase I study of irinotecan, oxaliplatin, and capecitabine.
Invest New Drugs
; 31(6): 1559-67, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114122
11.
Phase 2 trial of pemetrexed in children and adolescents with refractory solid tumors: a Children's Oncology Group study.
Pediatr Blood Cancer
; 60(2): 237-41, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22745043
12.
MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming.
Commun Biol
; 6(1): 215, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36823213
13.
Dominant-negative heterozygous mutations in AIRE confer diverse autoimmune phenotypes.
iScience
; 26(6): 106818, 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37235056
14.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Sci Adv
; 8(49): eabq8437, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36490346
15.
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Nat Commun
; 12(1): 2901, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006870
16.
Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM.
J Neurooncol
; 99(1): 73-80, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20063115
17.
Phase I trial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: a Children's Oncology Group phase I consortium study.
Pediatr Blood Cancer
; 54(4): 538-45, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20049936
18.
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation.
Genome Biol
; 21(1): 247, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32933554
19.
Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen.
JAMA
; 302(13): 1429-36, 2009 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19809024
20.
A Phase II Study of Alisertib in Children with Recurrent/Refractory Solid Tumors or Leukemia: Children's Oncology Group Phase I and Pilot Consortium (ADVL0921).
Clin Cancer Res
; 25(11): 3229-3238, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30777875