Detalhe da pesquisa
1.
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Cell
; 182(4): 976-991.e19, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32702314
2.
Alzheimer's-Causing Mutations Shift Aß Length by Destabilizing γ-Secretase-Aßn Interactions.
Cell
; 170(3): 443-456.e14, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753424
3.
Alzheimer's-causing mutations shift Aß length by destabilizing γ-secretase-Aßn interactions.
Cell
; 184(8): 2257-2258, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861967
4.
G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.
Proc Natl Acad Sci U S A
; 119(40): e2204828119, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36161942
5.
Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aß plaques in mouse and human brains.
J Neurochem
; 2024 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372586
6.
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer's disease.
J Neuroinflammation
; 21(1): 55, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383481
7.
Sex-dependent cholinergic effects on amyloid pathology: A translational study.
Alzheimers Dement
; 20(2): 995-1012, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37846816
8.
Genetic Mapping of APP and Amyloid-ß Biology Modulation by Trisomy 21.
J Neurosci
; 42(33): 6453-6468, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35835549
9.
Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APPNL-F/NL-F mouse model of Alzheimer's disease.
Neurobiol Dis
; 184: 106219, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37422091
10.
Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in AppNL-G-F/NL-G-F mice.
Neurobiol Dis
; 182: 106151, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37172910
11.
Cryo-EM structures of amyloid-ß filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol
; 145(3): 325-333, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36611124
12.
Somatostatin-evoked Aß catabolism in the brain: Mechanistic involvement of α-endosulfine-KATP channel pathway.
Mol Psychiatry
; 27(3): 1816-1828, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34737456
13.
Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.
Mol Psychiatry
; 27(7): 3024-3033, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296808
14.
Modality-Specific Impairment of Hippocampal CA1 Neurons of Alzheimer's Disease Model Mice.
J Neurosci
; 41(24): 5315-5329, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980545
15.
A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid ß peptide.
J Biol Chem
; 297(3): 101004, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329683
16.
Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing.
Neurobiol Dis
; 172: 105820, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35843448
17.
Impairment of ciliary dynamics in an APP knock-in mouse model of Alzheimer's disease.
Biochem Biophys Res Commun
; 610: 85-91, 2022 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35453040
18.
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
Arterioscler Thromb Vasc Biol
; 41(5): 1694-1709, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761765
19.
ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.
Proc Natl Acad Sci U S A
; 116(47): 23790-23796, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690660
20.
Suppression of amyloid-ß secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
J Neurochem
; 159(3): 603-617, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34379812