Pesquisa | BVS Violência e Saúde

1.

ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis.

Leong, Wei Zhong; Tan, Shi Hao; Ngoc, Phuong Cao Thi; Amanda, Stella; Yam, Alice Wei Yee; Liau, Wei-Siang; Gong, Zhiyuan; Lawton, Lee N; Tenen, Daniel G; Sanda, Takaomi.

Genes Dev ; 31(23-24): 2343-2360, 2017 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-29326336

2.

Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma.

Zhou, Jianbiao; Toh, Sabrina Hui-Min; Tan, Tze King; Balan, Kalpnaa; Lim, Jing Quan; Tan, Tuan Zea; Xiong, Sinan; Jia, Yunlu; Ng, Siok-Bian; Peng, Yanfen; Jeyasekharan, Anand D; Fan, Shuangyi; Lim, Soon Thye; Ong, Chin-Ann Johnny; Ong, Choon Kiat; Sanda, Takaomi; Chng, Wee-Joo.

Mol Cancer ; 22(1): 69, 2023 04 10.

Artigo em Inglês | MEDLINE | ID: mdl-37032358

3.

Regulatory mechanisms and context-dependent roles of TAL1 in T-cell acute lymphoblastic leukemia.

Ong, Jolynn Zu Lin; Tan, Tze King; Wang, Lu; Tan, Shi Hao; Sanda, Takaomi.

Haematologica ; 2023 Oct 19.

Artigo em Inglês | MEDLINE | ID: mdl-37855064

4.

Targeting dual oncogenic machineries driven by TAL1 and PI3K-AKT pathways in T-cell acute lymphoblastic leukemia.

Lim, Fang Qi; Chan, Allison Si-Yu; Yokomori, Rui; Huang, Xiao Zi; Theardy, Madelaine Skolastika; Yeoh, Allen Eng Juh; Tan, Shi Hao; Sanda, Takaomi.

Haematologica ; 108(2): 367-381, 2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-36073513

5.

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.

Sidi, Samuel; Sanda, Takaomi; Kennedy, Richard D; Hagen, Andreas T; Jette, Cicely A; Hoffmans, Raymond; Pascual, Jennifer; Imamura, Shintaro; Kishi, Shuji; Amatruda, James F; Kanki, John P; Green, Douglas R; D'Andrea, Alan A; Look, A Thomas.

Cell ; 133(5): 864-77, 2008 May 30.

Artigo em Inglês | MEDLINE | ID: mdl-18510930

6.

Feed-forward regulatory loop driven by IRF4 and NF-κB in adult T-cell leukemia/lymphoma.

Wong, Regina Wan Ju; Tan, Tze King; Amanda, Stella; Ngoc, Phuong Cao Thi; Leong, Wei Zhong; Tan, Shi Hao; Asamitsu, Kaori; Hibi, Yurina; Ueda, Ryuzo; Okamoto, Takashi; Ishida, Takashi; Iida, Shinsuke; Sanda, Takaomi.

Blood ; 135(12): 934-947, 2020 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-31972002

7.

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.

Tan, Shi Hao; Leong, Wei Zhong; Ngoc, Phuong Cao Thi; Tan, Tze King; Bertulfo, Fatima Carla; Lim, Mei Chee; An, Omer; Li, Zhenhua; Yeoh, Allen Eng Juh; Fullwood, Melissa J; Tenen, Daniel G; Sanda, Takaomi.

Blood ; 134(3): 239-251, 2019 07 18.

Artigo em Inglês | MEDLINE | ID: mdl-31076442

8.

Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia.

Zhang, Chujing; Amanda, Stella; Wang, Cheng; King Tan, Tze; Zulfaqar Ali, Muhammad; Zhong Leong, Wei; Moy Ng, Ley; Kitajima, Shojiro; Li, Zhenhua; Eng Juh Yeoh, Allen; Hao Tan, Shi; Sanda, Takaomi.

Haematologica ; 106(6): 1545-1558, 2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-32414855

9.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Kwiatkowski, Nicholas; Zhang, Tinghu; Rahl, Peter B; Abraham, Brian J; Reddy, Jessica; Ficarro, Scott B; Dastur, Anahita; Amzallag, Arnaud; Ramaswamy, Sridhar; Tesar, Bethany; Jenkins, Catherine E; Hannett, Nancy M; McMillin, Douglas; Sanda, Takaomi; Sim, Taebo; Kim, Nam Doo; Look, Thomas; Mitsiades, Constantine S; Weng, Andrew P; Brown, Jennifer R; Benes, Cyril H; Marto, Jarrod A; Young, Richard A; Gray, Nathanael S.

Nature ; 511(7511): 616-20, 2014 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-25043025

10.

PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.

Ando, Kiyohiro; Kernan, Jennifer L; Liu, Peter H; Sanda, Takaomi; Logette, Emmanuelle; Tschopp, Jurg; Look, A Thomas; Wang, Jianlong; Bouchier-Hayes, Lisa; Sidi, Samuel.

Mol Cell ; 47(5): 681-93, 2012 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-22854598

11.

Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia.

Wong, Regina Wan Ju; Ngoc, Phuong Cao Thi; Leong, Wei Zhong; Yam, Alice Wei Yee; Zhang, Tinghu; Asamitsu, Kaori; Iida, Shinsuke; Okamoto, Takashi; Ueda, Ryuzo; Gray, Nathanael S; Ishida, Takashi; Sanda, Takaomi.

Blood ; 130(21): 2326-2338, 2017 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-28978570

12.

Cyclin-dependent kinase 9 as a potential specific molecular target in NK-cell leukemia/lymphoma.

Kinoshita, Shiori; Ishida, Takashi; Ito, Asahi; Narita, Tomoko; Masaki, Ayako; Suzuki, Susumu; Yoshida, Takashi; Ri, Masaki; Kusumoto, Shigeru; Komatsu, Hirokazu; Shimizu, Norio; Inagaki, Hiroshi; Kuroda, Taruho; Scholz, Arne; Ueda, Ryuzo; Sanda, Takaomi; Iida, Shinsuke.

Haematologica ; 103(12): 2059-2068, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30076184

13.

Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia.

Wong, Regina Wan Ju; Ishida, Takashi; Sanda, Takaomi.

Molecules ; 23(5)2018 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-29724031

14.

[Understanding of molecular pathogenesis of T-cell leukemia by super-enhancer profiling].

Sanda, Takaomi.

Rinsho Ketsueki ; 59(7): 899-908, 2018.

Artigo em Japonês | MEDLINE | ID: mdl-30078801

15.

Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

Akahane, Koshi; Li, Zhaodong; Etchin, Julia; Berezovskaya, Alla; Gjini, Evisa; Masse, Craig E; Miao, Wenyan; Rocnik, Jennifer; Kapeller, Rosana; Greenwood, Jeremy R; Tiv, Hong; Sanda, Takaomi; Weinstock, David M; Look, A Thomas.

Br J Haematol ; 177(2): 271-282, 2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28295194

16.

Roles of the RUNX1 Enhancer in Normal Hematopoiesis and Leukemogenesis.

Liau, Wei-Siang; Ngoc, Phuong Cao Thi; Sanda, Takaomi.

Adv Exp Med Biol ; 962: 139-147, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28299656

17.

Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.

Barceló, Carles; Etchin, Julia; Mansour, Marc R; Sanda, Takaomi; Ginesta, Mireia M; Sanchez-Arévalo Lobo, Victor J; Real, Francisco X; Capellà, Gabriel; Estanyol, Josep M; Jaumot, Montserrat; Look, A Thomas; Agell, Neus.

Gastroenterology ; 147(4): 882-892.e8, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-24998203

18.

RUNX1 in T-ALL: tumor suppressive or oncogenic?

Sanda, Takaomi.

Blood ; 130(15): 1686-1688, 2017 10 12.

Artigo em Inglês | MEDLINE | ID: mdl-29025715

19.

Activating mutations in ALK provide a therapeutic target in neuroblastoma.

George, Rani E; Sanda, Takaomi; Hanna, Megan; Fröhling, Stefan; Luther, William; Zhang, Jianming; Ahn, Yebin; Zhou, Wenjun; London, Wendy B; McGrady, Patrick; Xue, Liquan; Zozulya, Sergey; Gregor, Vlad E; Webb, Thomas R; Gray, Nathanael S; Gilliland, D Gary; Diller, Lisa; Greulich, Heidi; Morris, Stephan W; Meyerson, Matthew; Look, A Thomas.

Nature ; 455(7215): 975-8, 2008 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-18923525

20.

Deciphering the regulatory landscape of murine splenic response to anemic stress at single-cell resolution.

Yang, Chong; Yokomori, Rui; Chua, Lee Hui; Tan, Shi Hao; Koh, Mun Yee; Totani, Haruhito; Sanda, Takaomi; Suda, Toshio.

Blood Adv ; 8(7): 1651-1666, 2024 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-38315834

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