Pesquisa | BVS Violência e Saúde

1.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.

Zhou, Tongqing; Lynch, Rebecca M; Chen, Lei; Acharya, Priyamvada; Wu, Xueling; Doria-Rose, Nicole A; Joyce, M Gordon; Lingwood, Daniel; Soto, Cinque; Bailer, Robert T; Ernandes, Michael J; Kong, Rui; Longo, Nancy S; Louder, Mark K; McKee, Krisha; O'Dell, Sijy; Schmidt, Stephen D; Tran, Lillian; Yang, Zhongjia; Druz, Aliaksandr; Luongo, Timothy S; Moquin, Stephanie; Srivatsan, Sanjay; Yang, Yongping; Zhang, Baoshan; Zheng, Anqi; Pancera, Marie; Kirys, Tatsiana; Georgiev, Ivelin S; Gindin, Tatyana; Peng, Hung-Pin; Yang, An-Suei; Mullikin, James C; Gray, Matthew D; Stamatatos, Leonidas; Burton, Dennis R; Koff, Wayne C; Cohen, Myron S; Haynes, Barton F; Casazza, Joseph P; Connors, Mark; Corti, Davide; Lanzavecchia, Antonio; Sattentau, Quentin J; Weiss, Robin A; West, Anthony P; Bjorkman, Pamela J; Scheid, Johannes F; Nussenzweig, Michel C; Shapiro, Lawrence.

Cell ; 161(6): 1280-92, 2015 Jun 04.

Artigo em Inglês | MEDLINE | ID: mdl-26004070

2.

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

LaBranche, Celia C; McGuire, Andrew T; Gray, Matthew D; Behrens, Shay; Chen, Xuejun; Zhou, Tongqing; Sattentau, Quentin J; Peacock, James; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Tang, Haili; Perez, Lautaro G; Saunders, Kevin O; Kwong, Peter D; Mascola, John R; Haynes, Barton F; Stamatatos, Leonidas; Montefiori, David C.

PLoS Pathog ; 15(3): e1007646, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30913265

3.

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.

LaBranche, Celia C; Henderson, Rory; Hsu, Allen; Behrens, Shay; Chen, Xuejun; Zhou, Tongqing; Wiehe, Kevin; Saunders, Kevin O; Alam, S Munir; Bonsignori, Mattia; Borgnia, Mario J; Sattentau, Quentin J; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Liao, Hua-Xin; Williams, Wilton B; Peacock, James; Tang, Haili; Perez, Lautaro G; Edwards, Robert J; Kepler, Thomas B; Korber, Bette T; Kwong, Peter D; Mascola, John R; Acharya, Priyamvada; Haynes, Barton F; Montefiori, David C.

PLoS Pathog ; 15(9): e1008026, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31527908

4.

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.

LaBranche, Celia C; Henderson, Rory; Hsu, Allen; Behrens, Shay; Chen, Xuejun; Zhou, Tongqing; Wiehe, Kevin; Saunders, Kevin O; Alam, S Munir; Bonsignori, Mattia; Borgnia, Mario J; Sattentau, Quentin J; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Liao, Hua-Xin; Williams, Wilton B; Peacock, James; Tang, Haili; Perez, Lautaro G; Edwards, Robert J; Kepler, Thomas B; Korber, Bette T; Kwong, Peter D; Mascola, John R; Acharya, Priyamvada; Haynes, Barton F; Montefiori, David C.

PLoS Pathog ; 15(12): e1008200, 2019 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-31790514

5.

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.

Schiffner, Torben; Pallesen, Jesper; Russell, Rebecca A; Dodd, Jonathan; de Val, Natalia; LaBranche, Celia C; Montefiori, David; Tomaras, Georgia D; Shen, Xiaoying; Harris, Scarlett L; Moghaddam, Amin E; Kalyuzhniy, Oleksandr; Sanders, Rogier W; McCoy, Laura E; Moore, John P; Ward, Andrew B; Sattentau, Quentin J.

PLoS Pathog ; 14(5): e1006986, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29746590

6.

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

LaBranche, Celia C; McGuire, Andrew T; Gray, Matthew D; Behrens, Shay; Kwong, Peter D; Chen, Xuejun; Zhou, Tongqing; Sattentau, Quentin J; Peacock, James; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Tang, Haili; Perez, Lautaro G; Chen, Xuejun; Saunders, Kevin O; Kwong, Peter D; Mascola, John R; Haynes, Barton F; Stamatatos, Leonidas; Montefiori, David C.

PLoS Pathog ; 14(11): e1007431, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30395637

7.

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens.

Schiffner, Torben; de Val, Natalia; Russell, Rebecca A; de Taeye, Steven W; de la Peña, Alba Torrents; Ozorowski, Gabriel; Kim, Helen J; Nieusma, Travis; Brod, Florian; Cupo, Albert; Sanders, Rogier W; Moore, John P; Ward, Andrew B; Sattentau, Quentin J.

J Virol ; 90(2): 813-28, 2016 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-26512083

8.

High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.

Duncan, Christopher J A; Williams, James P; Schiffner, Torben; Gärtner, Kathleen; Ochsenbauer, Christina; Kappes, John; Russell, Rebecca A; Frater, John; Sattentau, Quentin J.

J Virol ; 88(4): 2025-34, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24307588

9.

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.

Sheppard, Neil C; Brinckmann, Sarah A; Gartlan, Kate H; Puthia, Manoj; Svanborg, Catharina; Krashias, George; Eisenbarth, Stephanie C; Flavell, Richard A; Sattentau, Quentin J; Wegmann, Frank.

Int Immunol ; 26(10): 531-8, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-24844701

10.

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.

Drexhage, Linnea Z; Zhang, Shengpan; Dupont, Maeva; Ragaller, Franziska; Sjule, Ellen; Cabezas-Caballero, Jose; Deimel, Lachlan P; Robertson, Helen; Russell, Rebecca A; Dushek, Omer; Sezgin, Erdinc; Karaji, Niloofar; Sattentau, Quentin J.

Nat Commun ; 15(1): 541, 2024 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-38225245

11.

Development of prophylactic vaccines against HIV-1.

Schiffner, Torben; Sattentau, Quentin J; Dorrell, Lucy.

Retrovirology ; 10: 72, 2013 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-23866844

12.

The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.

Jolly, Clare; Welsch, Sonja; Michor, Stefanie; Sattentau, Quentin J.

PLoS Pathog ; 7(9): e1002226, 2011 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-21909273

13.

Reactive carbonyls are a major Th2-inducing damage-associated molecular pattern generated by oxidative stress.

Moghaddam, Amin E; Gartlan, Kate H; Kong, Leopold; Sattentau, Quentin J.

J Immunol ; 187(4): 1626-33, 2011 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-21742965

14.

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines.

Moghaddam, Amin; Olszewska, Wieslawa; Wang, Belinda; Tregoning, John S; Helson, Rebecca; Sattentau, Quentin J; Openshaw, Peter J M.

Nat Med ; 12(8): 905-7, 2006 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-16862151

15.

Attachment factors.

Jolly, Clare L; Sattentau, Quentin J.

Adv Exp Med Biol ; 790: 1-23, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23884583

16.

Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.

Martin, Gregory M; Russell, Rebecca A; Mundsperger, Philip; Harris, Scarlett; Jovanoska, Lu; Trajano, Luiza Farache; Schiffner, Torben; Fabian, Katalin; Tolazzi, Monica; Scarlatti, Gabriella; McFarlane, Leon; Cheeseman, Hannah; Aldon, Yoann; Schermer, Edith E; Breemen, Marielle; Sliepen, Kwinten; Katinger, Dietmar; Kunert, Renate; Sanders, Rogier W; Shattock, Robin; Ward, Andrew B; Sattentau, Quentin J.

NPJ Vaccines ; 8(1): 101, 2023 Jul 13.

Artigo em Inglês | MEDLINE | ID: mdl-37443366

17.

Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.

Welsch, Sonja; Groot, Fedde; Kräusslich, Hans-Georg; Keppler, Oliver T; Sattentau, Quentin J.

J Virol ; 85(15): 7922-7, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21613397

18.

Vaccinology: A sweet cleft in HIV's armour.

Sattentau, Quentin J.

Nature ; 480(7377): 324-5, 2011 Dec 14.

Artigo em Inglês | MEDLINE | ID: mdl-22170674

19.

Glycans in HIV-1 vaccine design - engaging the shield.

Deimel, Lachlan P; Xue, Xiaochao; Sattentau, Quentin J.

Trends Microbiol ; 30(9): 866-881, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35279348

20.

Shared sugars - parasite glycan homology in HIV-1 vaccine design.

Deimel, Lachlan P; Sattentau, Quentin J.

Trends Parasitol ; 38(7): 498-500, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35501266

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