Detalhe da pesquisa
1.
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways.
Nat Rev Mol Cell Biol
; 24(5): 312-333, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543934
2.
Alzheimer's-Causing Mutations Shift Aß Length by Destabilizing γ-Secretase-Aßn Interactions.
Cell
; 170(3): 443-456.e14, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753424
3.
Alzheimer's-causing mutations shift Aß length by destabilizing γ-secretase-Aßn interactions.
Cell
; 184(8): 2257-2258, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861967
4.
Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.
Nat Immunol
; 18(3): 313-320, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28068307
5.
Activation of goblet-cell stress sensor IRE1ß is controlled by the mucin chaperone AGR2.
EMBO J
; 43(5): 695-718, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177501
6.
Design of protein-binding proteins from the target structure alone.
Nature
; 605(7910): 551-560, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332283
7.
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rß1.
Immunity
; 48(1): 45-58.e6, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29287995
8.
Structural basis of cytokine-mediated activation of ALK family receptors.
Nature
; 600(7887): 143-147, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34646012
9.
Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
N Engl J Med
; 388(24): 2253-2261, 2023 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37314706
10.
Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature
; 568(7753): 571-575, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30944476
11.
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping.
Proc Natl Acad Sci U S A
; 118(47)2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34789568
12.
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity.
J Biol Chem
; 298(5): 101908, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35398099
13.
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding.
J Biol Chem
; 298(2): 101574, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007536
14.
Minimal epitope for Mannitou IgM on paucimannose-carrying glycoproteins.
Glycobiology
; 31(8): 1005-1017, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33909073
15.
Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.
Plant Cell
; 30(10): 2573-2593, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018157
16.
Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.
Nat Chem Biol
; 15(6): 641-649, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31011214
17.
IL-33trap is a novel IL-33-neutralizing biologic that inhibits allergic airway inflammation.
J Allergy Clin Immunol
; 144(1): 204-215, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30876911
18.
Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis: A molecular insight.
Clin Immunol
; 206: 15-22, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30196070
19.
Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Environ Microbiol
; 19(10): 3930-3937, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28488744
20.
The Charcot-Leyden crystal protein galectin-10 is not a major determinant of human regulatory T-cell function.
Allergy
; 77(9): 2818-2821, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35491437