Pesquisa | BVS Violência e Saúde

1.

IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.

Krueger, James G; Wharton, Keith A; Schlitt, Thomas; Suprun, Maria; Torene, Rebecca I; Jiang, Xiaoyu; Wang, Claire Q; Fuentes-Duculan, Judilyn; Hartmann, Nicole; Peters, Thomas; Koroleva, Irina; Hillenbrand, Rainer; Letzkus, Martin; Yu, Xiaojing; Li, Yue; Glueck, Anton; Hasselberg, Anke; Flannery, Brian; Suárez-Fariñas, Mayte; Hueber, Wolfgang.

J Allergy Clin Immunol ; 144(3): 750-763, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31129129

2.

Dynamics of gene regulatory networks and their dependence on network topology and quantitative parameters - the case of phage λ.

Ruklisa, Dace; Brazma, Alvis; Cerans, Karlis; Schlitt, Thomas; Viksna, Juris.

BMC Bioinformatics ; 20(1): 296, 2019 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-31151381

3.

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

Prescott, Natalie J; Lehne, Benjamin; Stone, Kristina; Lee, James C; Taylor, Kirstin; Knight, Jo; Papouli, Efterpi; Mirza, Muddassar M; Simpson, Michael A; Spain, Sarah L; Lu, Grace; Fraternali, Franca; Bumpstead, Suzannah J; Gray, Emma; Amar, Ariella; Bye, Hannah; Green, Peter; Chung-Faye, Guy; Hayee, Bu'Hussain; Pollok, Richard; Satsangi, Jack; Parkes, Miles; Barrett, Jeffrey C; Mansfield, John C; Sanderson, Jeremy; Lewis, Cathryn M; Weale, Michael E; Schlitt, Thomas; Mathew, Christopher G.

PLoS Genet ; 11(2): e1004955, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25671699

4.

Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease.

Dand, Nick; Schulz, Reiner; Weale, Michael E; Southgate, Laura; Oakey, Rebecca J; Simpson, Michael A; Schlitt, Thomas.

Hum Mutat ; 36(12): 1135-44, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26394720

5.

BioGranat-IG: a network analysis tool to suggest mechanisms of genetic heterogeneity from exome-sequencing data.

Dand, Nick; Sprengel, Frauke; Ahlers, Volker; Schlitt, Thomas.

Bioinformatics ; 29(6): 733-41, 2013 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-23361329

6.

Predicting the functional consequences of non-synonymous DNA sequence variants--evaluation of bioinformatics tools and development of a consensus strategy.

Frousios, Kimon; Iliopoulos, Costas S; Schlitt, Thomas; Simpson, Michael A.

Genomics ; 102(4): 223-8, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23831115

7.

The Iranian Corona Stress Study: Psychological Impacts of COVID-19 Pandemic in an Iranian Population.

Sabouhi, Sadegh; Vaezi, Atefeh; Sharbafchi, Mohammad Reza; Aerni, Amanda; Bentz, Dorothee; Coynel, David; de Quervain, Dominique; Fehlmann, Bernhard; Freytag, Virginie; Gerhards, Christiane; Papassotiropoulos, Andreas; Schicktanz, Nathalie; Schlitt, Thomas; Zimmer, Anja; Zuber, Priska; Amini, Ehssan.

Int J Prev Med ; 13: 129, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36452472

8.

Exome localization of complex disease association signals.

Lehne, Benjamin; Lewis, Cathryn M; Schlitt, Thomas.

BMC Genomics ; 12: 92, 2011 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-21284873

9.

Protein-protein interaction databases: keeping up with growing interactomes.

Lehne, Benjamin; Schlitt, Thomas.

Hum Genomics ; 3(3): 291-7, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19403463

10.

Current approaches to gene regulatory network modelling.

Schlitt, Thomas; Brazma, Alvis.

BMC Bioinformatics ; 8 Suppl 6: S9, 2007 Sep 27.

Artigo em Inglês | MEDLINE | ID: mdl-17903290

11.

Extremophiles in an Antarctic Marine Ecosystem.

Dickinson, Iain; Goodall-Copestake, William; Thorne, Michael A S; Schlitt, Thomas; Ávila-Jiménez, Maria L; Pearce, David A.

Microorganisms ; 4(1)2016 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-27681902

12.

Modelling gene networks at different organisational levels.

Schlitt, Thomas; Brazma, Alvis.

FEBS Lett ; 579(8): 1859-66, 2005 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-15763564

13.

Approaches to modeling gene regulatory networks: a gentle introduction.

Schlitt, Thomas.

Methods Mol Biol ; 1021: 13-35, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23715978

14.

HSM - a hybrid system based approach for modelling intracellular networks.

Brazma, Alvis; Cerans, Karlis; Ruklisa, Dace; Schlitt, Thomas; Viksna, Juris.

Gene ; 518(1): 70-7, 2013 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-23266641

15.

Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes.

Lehne, Benjamin; Schlitt, Thomas.

Pharmacogenomics ; 13(16): 1967-78, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23215889

16.

From SNPs to genes: disease association at the gene level.

Lehne, Benjamin; Lewis, Cathryn M; Schlitt, Thomas.

PLoS One ; 6(6): e20133, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21738570

17.

Modelling in molecular biology: describing transcription regulatory networks at different scales.

Schlitt, Thomas; Brazma, Alvis.

Philos Trans R Soc Lond B Biol Sci ; 361(1467): 483-94, 2006 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-16524837

18.

Learning about gene regulatory networks from gene deletion experiments.

Schlitt, Thomas; Brazma, Alvis.

Comp Funct Genomics ; 3(6): 499-503, 2002.

Artigo em Inglês | MEDLINE | ID: mdl-18629255

19.

From gene networks to gene function.

Schlitt, Thomas; Palin, Kimmo; Rung, Johan; Dietmann, Sabine; Lappe, Michael; Ukkonen, Esko; Brazma, Alvis.

Genome Res ; 13(12): 2568-76, 2003 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-14656964

20.

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain.

Tenbaum, Stephan P; Juenemann, Stefan; Schlitt, Thomas; Bernal, Juan; Renkawitz, Rainer; Muñoz, Alberto; Baniahmad, Aria.

Dev Biol ; 254(1): 149-60, 2003 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-12606288

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IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.

Dynamics of gene regulatory networks and their dependence on network topology and quantitative parameters - the case of phage λ.

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease.

BioGranat-IG: a network analysis tool to suggest mechanisms of genetic heterogeneity from exome-sequencing data.

Predicting the functional consequences of non-synonymous DNA sequence variants--evaluation of bioinformatics tools and development of a consensus strategy.

The Iranian Corona Stress Study: Psychological Impacts of COVID-19 Pandemic in an Iranian Population.

Exome localization of complex disease association signals.

Protein-protein interaction databases: keeping up with growing interactomes.

Current approaches to gene regulatory network modelling.

Extremophiles in an Antarctic Marine Ecosystem.

Modelling gene networks at different organisational levels.

Approaches to modeling gene regulatory networks: a gentle introduction.

HSM - a hybrid system based approach for modelling intracellular networks.

Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes.

From SNPs to genes: disease association at the gene level.

Modelling in molecular biology: describing transcription regulatory networks at different scales.

Learning about gene regulatory networks from gene deletion experiments.

From gene networks to gene function.

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain.