Detalhe da pesquisa
1.
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
EMBO J
; 42(10): e111699, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36912136
2.
(-)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy.
Muscle Nerve
; 63(2): 239-249, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33125736
3.
Safety and efficacy of (+)-epicatechin in subjects with Friedreich's ataxia: A phase II, open-label, prospective study.
J Inherit Metab Dis
; 44(2): 502-514, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32677106
4.
11-ß-hydroxysterols as possible endogenous stimulators of mitochondrial biogenesis as inferred from epicatechin molecular mimicry.
Pharmacol Res
; 151: 104540, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31722227
5.
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.
J Biol Chem
; 287(48): 40732-44, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035112
6.
Nicorandil, a K(atp) channel opener, alleviates chronic renal injury by targeting podocytes and macrophages.
Am J Physiol Renal Physiol
; 303(3): F339-49, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22622455
7.
Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy.
Am J Physiol Renal Physiol
; 303(9): F1264-74, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22933302
8.
Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS-deficient mouse.
Am J Physiol Renal Physiol
; 302(9): F1151-60, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22338086
9.
Stimulatory effects of (-)-epicatechin and its enantiomer (+)-epicatechin on mouse frontal cortex neurogenesis markers and short-term memory: proof of concept.
Food Funct
; 12(8): 3504-3515, 2021 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900336
10.
A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints.
Food Funct
; 9(1): 307-319, 2018 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29171848
11.
Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.
Anticancer Res
; 27(6B): 4149-57, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229422
12.
Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo.
Clin Cancer Res
; 12(14 Pt 1): 4315-30, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16857807
13.
B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation.
Circ Res
; 94(4): 453-61, 2004 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14726474
14.
A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects.
Int J Cardiol
; 223: 500-506, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27552564
15.
p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells.
Oncogene
; 23(54): 8766-76, 2004 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15480425
16.
Myocardial contrast echocardiography can be used to assess the microvascular response to vascular endothelial growth factor-121.
Circulation
; 105(6): 759-65, 2002 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-11839634
17.
Targeted in vivo labeling of receptors for vascular endothelial growth factor: approach to identification of ischemic tissue.
Circulation
; 108(1): 97-103, 2003 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-12821549
18.
B-type natriuretic peptide for the treatment of congestive heart failure.
Curr Opin Pharmacol
; 2(2): 142-7, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11950624
19.
Affymetrix oligonucleotide analysis of gene expression in the injured heart.
Methods Mol Med
; 112: 305-20, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16010026
20.
Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers.
Food Funct
; 6(3): 824-33, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25598082