Pesquisa | BVS Violência e Saúde

1.

Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia.

Lasaga, Miren; Río, Paula; Vilas-Zornoza, Amaia; Planell, Nuria; Navarro, Susana; Alignani, Diego; Fernández-Varas, Beatriz; Mouzo, Daniel; Zubicaray, Josune; Pujol, Roser M; Nicoletti, Eileen; Schwartz, Jonathan D; Sevilla, Julián; Ainciburi, Marina; Ullate-Agote, Asier; Surrallés, Jordi; Perona, Rosario; Sastre, Leandro; Prosper, Felipe; Gomez-Cabrero, David; Bueren, Juan A.

Haematologica ; 108(10): 2652-2663, 2023 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-37021532

2.

Natural gene therapy by reverse mosaicism leads to improved hematology in Fanconi anemia patients.

Ramírez, María José; Pujol, Roser; Trujillo-Quintero, Juan Pablo; Minguillón, Jordi; Bogliolo, Massimo; Río, Paula; Navarro, Susana; Casado, José A; Badell, Isabel; Carrasco, Estela; Balmaña, Judith; Català, Albert; Sevilla, Julián; Beléndez, Cristina; Argilés, Bienvenida; López, Mónica; Díaz de Heredia, Cristina; Rao, Gayatri; Nicoletti, Eileen; Schwartz, Jonathan D; Bueren, Juan A; Surrallés, Jordi.

Am J Hematol ; 96(8): 989-999, 2021 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-33984160

3.

Mitapivat versus Placebo for Pyruvate Kinase Deficiency.

Shah, Ami J; Schwartz, Jonathan D; Segovia, Jose C.

N Engl J Med ; 386(26): 2538-2539, 2022 06 30.

Artigo em Inglês | MEDLINE | ID: mdl-35767453

4.

Mosaicism in Fanconi anemia: concise review and evaluation of published cases with focus on clinical course of blood count normalization.

Nicoletti, Eileen; Rao, Gayatri; Bueren, Juan A; Río, Paula; Navarro, Susana; Surrallés, Jordi; Choi, Grace; Schwartz, Jonathan D.

Ann Hematol ; 99(5): 913-924, 2020 May.

Artigo em Inglês | MEDLINE | ID: mdl-32065290

5.

Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at 10-fold lower cell doses.

Haworth, Kevin G; Ironside, Christina; Ramirez, Megan A; Weitz, Sarah; Beard, Brian C; Schwartz, Jonathan D; Adair, Jennifer E; Kiem, Hans-Peter.

J Gene Med ; 20(10-11): e3050, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30129972

6.

Tisagenlecleucel in Diffuse Large B-Cell Lymphoma.

Schwartz, Jonathan D.

N Engl J Med ; 380(16): 1585-1586, 2019 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-30995383

7.

Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD.

Schwartz, Jonathan D; Barcellini, Wilma; Grace, Rachel F; Bianchi, Paola; Zanella, Alberto; López Lorenzo, José Luis; Sevilla, Julián; Shah, Ami J; Glader, Bertil; Nicoletti, Eileen; Navarro Ordoñez, Susana; Segovia, José Carlos.

Am J Hematol ; 97(3): E120-E125, 2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-34989415

8.

Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trial.

Zhu, Andrew X; Park, Joon Oh; Ryoo, Baek-Yeol; Yen, Chia-Jui; Poon, Ronnie; Pastorelli, Davide; Blanc, Jean-Frederic; Chung, Hyun Cheol; Baron, Ari D; Pfiffer, Tulio Eduardo Flesch; Okusaka, Takuji; Kubackova, Katerina; Trojan, Jorg; Sastre, Javier; Chau, Ian; Chang, Shao-Chun; Abada, Paolo B; Yang, Ling; Schwartz, Jonathan D; Kudo, Masatoshi.

Lancet Oncol ; 16(7): 859-70, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-26095784

9.

Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial.

Fuchs, Charles S; Tomasek, Jiri; Yong, Cho Jae; Dumitru, Filip; Passalacqua, Rodolfo; Goswami, Chanchal; Safran, Howard; Dos Santos, Lucas Vieira; Aprile, Giuseppe; Ferry, David R; Melichar, Bohuslav; Tehfe, Mustapha; Topuzov, Eldar; Zalcberg, John Raymond; Chau, Ian; Campbell, William; Sivanandan, Choondal; Pikiel, Joanna; Koshiji, Minori; Hsu, Yanzhi; Liepa, Astra M; Gao, Ling; Schwartz, Jonathan D; Tabernero, Josep.

Lancet ; 383(9911): 31-39, 2014 Jan 04.

Artigo em Inglês | MEDLINE | ID: mdl-24094768

10.

Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial.

Wilke, Hansjochen; Muro, Kei; Van Cutsem, Eric; Oh, Sang-Cheul; Bodoky, György; Shimada, Yasuhiro; Hironaka, Shuichi; Sugimoto, Naotoshi; Lipatov, Oleg; Kim, Tae-You; Cunningham, David; Rougier, Philippe; Komatsu, Yoshito; Ajani, Jaffer; Emig, Michael; Carlesi, Roberto; Ferry, David; Chandrawansa, Kumari; Schwartz, Jonathan D; Ohtsu, Atsushi.

Lancet Oncol ; 15(11): 1224-35, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25240821

11.

A phase 2, single-arm study of ramucirumab in patients with metastatic renal cell carcinoma with disease progression on or intolerance to tyrosine kinase inhibitor therapy.

Garcia, Jorge A; Hudes, Gary R; Choueiri, Toni K; Stadler, Walter M; Wood, Laura S; Gurtler, Jayne; Bhatia, Shailender; Joshi, Adarsh; Hozak, Rebecca R; Xu, Yihuan; Schwartz, Jonathan D; Thompson, John A.

Cancer ; 120(11): 1647-55, 2014 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-24577874

12.

An open-label phase II study evaluating the safety and efficacy of ramucirumab combined with mFOLFOX-6 as first-line therapy for metastatic colorectal cancer.

Garcia-Carbonero, Rocio; Rivera, Fernando; Maurel, Joan; Ayoub, Jean-Pierre M; Moore, Malcolm J; Cervantes, Andres; Asmis, Timothy R; Schwartz, Jonathan D; Nasroulah, Federico; Ballal, Shaila; Tabernero, Josep.

Oncologist ; 19(4): 350-1, 2014 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-24674871

13.

A phase II study of ramucirumab (IMC-1121B) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma.

Penson, Richard T; Moore, Kathleen M; Fleming, Gini F; Braly, Patricia; Schimp, Veronica; Nguyen, Hoa; Matulonis, Ursula A; Banerjee, Susana; Haluska, Paul; Gore, Martin; Bodurka, Diane C; Hozak, Rebecca R; Joshi, Adarsh; Xu, Yihuan; Schwartz, Jonathan D; McGuire, William P.

Gynecol Oncol ; 134(3): 478-85, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25016924

14.

Thrombotic microangiopathy following systemic AAV administration is dependent on anti-capsid antibodies.

Salabarria, Stephanie M; Corti, Manuela; Coleman, Kirsten E; Wichman, Megan B; Berthy, Julie A; D'Souza, Precilla; Tifft, Cynthia J; Herzog, Roland W; Elder, Melissa E; Shoemaker, Lawrence R; Leon-Astudillo, Carmen; Tavakkoli, Fatemeh; Kirn, David H; Schwartz, Jonathan D; Byrne, Barry J.

J Clin Invest ; 134(1)2024 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-37988172

15.

Advances in NK cell therapy for brain tumors.

Fares, Jawad; Davis, Zachary B; Rechberger, Julian S; Toll, Stephanie A; Schwartz, Jonathan D; Daniels, David J; Miller, Jeffrey S; Khatua, Soumen.

NPJ Precis Oncol ; 7(1): 17, 2023 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-36792722

16.

Predicting disease progression and the need for tumor-directed treatment in tectal plate gliomas.

Bauman, Megan M J; Giesken, Max B; Naylor, Ryan M; Keating, Gesina F; Schwartz, Jonathan D; Daniels, David J.

J Neurosurg Pediatr ; 32(3): 332-342, 2023 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-37347621

17.

Copeptin levels in hospitalized infants and children with suspected vasopressin-dependent disorders: a case series.

Al Nofal, Alaa; Hanna, Christian; Lteif, Aida N; Pittock, Siobhan T; Schwartz, Jonathan D; Brumbaugh, Jane E; Creo, Ana L.

J Pediatr Endocrinol Metab ; 36(5): 492-499, 2023 May 25.

Artigo em Inglês | MEDLINE | ID: mdl-37029788

18.

Drug delivery across the blood-brain barrier for the treatment of pediatric brain tumors - An update.

Power, Erica A; Rechberger, Julian S; Gupta, Sumit; Schwartz, Jonathan D; Daniels, David J; Khatua, Soumen.

Adv Drug Deliv Rev ; 185: 114303, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35460714

19.

Findings on Optical Coherence Tomography in Malignant Infantile Osteopetrosis.

Campagna, Giovanni A; Chew, Leila; Pettenkofer, Moritz; Nicoletti, Eileen; Schwartz, Jonathan D; Choi, Grace; Fernandes, Augustine O; Terrazas, Dayna; Kohn, Donald B; Tsui, Irena.

Ophthalmic Surg Lasers Imaging Retina ; 53(7): 398-402, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35858232

20.

Preclinical safety and efficacy of lentiviral-mediated gene therapy for leukocyte adhesion deficiency type I.

Mesa-Núñez, Cristina; Damián, Carlos; Fernández-García, María; Díez, Begoña; Rao, Gayatri; Schwartz, Jonathan D; Law, Ken M; Sevilla, Julián; Río, Paula; Yáñez, Rosa; Bueren, Juan A; Almarza, Elena.

Mol Ther Methods Clin Dev ; 26: 459-470, 2022 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-36092365

BVS Violência e Saúde

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: