Detalhe da pesquisa
1.
Simulation of pH-Dependent Conformational Transitions in Membrane Proteins: The CLC-ec1 Cl-/H+ Antiporter.
Molecules
; 26(22)2021 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834047
2.
A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs.
Molecules
; 24(11)2019 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31159491
3.
Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones.
Bioorg Med Chem Lett
; 26(7): 1827-1830, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26916440
4.
(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.
Mol Pharmacol
; 87(2): 197-206, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411367
5.
Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.
J Biol Chem
; 289(9): 5828-45, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366865
6.
Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.
Biochemistry
; 52(52): 9456-69, 2013 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24274581
7.
Novel insights into CB1 cannabinoid receptor signaling: a key interaction identified between the extracellular-3 loop and transmembrane helix 2.
J Pharmacol Exp Ther
; 345(2): 189-97, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426954
8.
CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol
; 8(81): eadf1426, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36867678
9.
Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction.
Methods Enzymol
; 593: 449-490, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28750815
10.
The therapeutic potential of orphan GPCRs, GPR35 and GPR55.
Front Pharmacol
; 6: 69, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25926795
11.
CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.
J Med Chem
; 57(21): 8777-91, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25272206
12.
Pregnenolone can protect the brain from cannabis intoxication.
Science
; 343(6166): 94-8, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24385629