Prevalence of occult anemia in an urban pediatric emergency department: what is our response?

OBJECTIVE: Treating or referring patients who are found to be anemic during pediatric emergency department (ED) encounters should lead to improved health in children and young adults. Before establishing guidelines how to approach the anemic in the pediatric ED, it is essential to determine the prevalence of anemia in the ED and our response to the presence of anemia. METHODS: We performed a retrospective cross-sectional study on hemoglobin levels from patients 1 to 23 years evaluated in an inner-city public hospital pediatric ED during a 12-month period. The primary outcome measure was the prevalence of prior unknown or "occult" anemia, stratified by age, sex, and insurance status. The secondary outcome was the proportion of patients with "occult" anemia who had their condition diagnosed during their ED encounter. Descriptive data analysis was performed. RESULTS: Our study population consisted of 2131 patients who had a complete blood count drawn in the ED. Prevalence of "occult" anemia was 13.9% (95% confidence interval [CI], 12.5%-15.4%). Proportions among the subpopulations were 14.8% (95% CI, 10.0%-19.5%) in preschool children, 16.3% (95% CI, 14.2%-18.3%) in females, 18.5% (95% CI, 15.4%-21.7%) in the uninsured, and 20.7% (95% CI, 16.5%-24.9%) in females of childbearing age without insurance. Only 24 patients (8%) with "occult" anemia had the condition identified on discharge. CONCLUSIONS: Anemia has a high prevalence in this pediatric ED population, especially among females of childbearing age and the uninsured. Pediatric emergency medicine physicians are missing on an opportunity to address a common health problem that is easily corrected with appropriate therapy and outpatient follow-up.

Rickettsia spp. 364D causing a cluster of eschar-associated illness, California.

We describe the clinical course of the first 3 pediatric cases infected with Rickettsia spp. 364D. Although the pathogen was identified in California ticks decades ago, only recently have human cases been documented. Clinical features are generally mild, characterized by eschar, fever, headache, malaise and lymphadenopathy. Antigenic similarity among rickettsiae leads to cross-reactive antibody responses; definitive diagnosis requires molecular methods.