Pesquisa | BVS Violência e Saúde

1.

A quality improvement initiative standardizing premedication for blood product transfusions.

Shahid, Sanam; Rosenzweig, Jaclyn; Troullioud Lucas, Alexandre; McThenia, Sheila S; Fong, Christina; Degliuomini, Melanie D; Wuest, David; Kaicker, Shipra; Slotkin, Emily K.

Pediatr Blood Cancer ; 71(1): e30753, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37899699

2.

Irinotecan dose schedule for the treatment of Ewing sarcoma.

Slotkin, Emily K; Meyers, Paul A.

Pediatr Blood Cancer ; 70(1): e30005, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36184748

3.

Chemotherapy-induced thrombocytopenia in pediatric oncology: Scope of the problem and opportunities for intervention.

Degliuomini, Melanie D; Armstrong, Katherine; Mauguen, Audrey; Slotkin, Emily K; Roberts, Stephen S; Dunkel, Ira J; Clouser, Mary; Ortiz, Michael V; Soff, Gerald A.

Pediatr Blood Cancer ; 69(10): e29776, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35593014

4.

TP53 mutations increase radioresistance in rhabdomyosarcoma and Ewing sarcoma.

Casey, Dana L; Pitter, Kenneth L; Wexler, Leonard H; Slotkin, Emily K; Gupta, Gaorav P; Wolden, Suzanne L.

Br J Cancer ; 125(4): 576-581, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34017087

5.

Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force.

Whittle, Sarah B; Offer, Katharine; Roberts, Ryan D; LeBlanc, Amy; London, Cheryl; Majzner, Robbie G; Huang, Alex Y; Houghton, Peter; Alejandro Sweet Cordero, E; Grohar, Patrick J; Isakoff, Michael; Bishop, Michael W; Stewart, Elizabeth; Slotkin, Emily K; Greengard, Emily; Borinstein, Scott C; Navid, Fariba; Gorlick, Richard; Janeway, Katherine A; Reed, Damon R; Hingorani, Pooja.

Pediatr Blood Cancer ; 68(9): e29188, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34137164

6.

Pediatric DDR inhibitor combinations: Are WEE1 there yet?

Slotkin, Emily K; Ortiz, Michael V; Glade Bender, Julia L.

Cancer ; 129(14): 2132-2134, 2023 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-37081596

7.

Towards a new era in the treatment of Ewing sarcoma.

Slotkin, Emily K; Tap, William D.

Lancet ; 400(10362): 1488-1489, 2022 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-36522196

8.

Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.

Spraggon, Lee; Martelotto, Luciano G; Hmeljak, Julija; Hitchman, Tyler D; Wang, Jiang; Wang, Lu; Slotkin, Emily K; Fan, Pang-Dian; Reis-Filho, Jorge S; Ladanyi, Marc.

J Pathol ; 242(1): 102-112, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28188619

9.

Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma.

Ortiz, Michael V; Magnan, Heather; Slotkin, Emily K; Ambati, Srikanth R; Chou, Alexander J; Wexler, Leonard H; Meyers, Paul A; Walsh, Michael F; Heaton, Todd; Girardi, Leonard N; Wolden, Suzanne L; Price, Anita P; Kennedy, Jennifer A; Zehir, Ahmet; Hameed, Meera; Berger, Michael F; Kentsis, Alex; Shukla, Neerav.

J Pediatr Hematol Oncol ; 39(8): e443-e445, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-28060130

10.

A single-center experience with undifferentiated embryonal sarcoma of the liver.

Mathias, Melissa D; Ambati, Srikanth R; Chou, Alexander J; Slotkin, Emily K; Wexler, Leonard H; Meyers, Paul A; Magnan, Heather.

Pediatr Blood Cancer ; 63(12): 2246-2248, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27427850

11.

Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center.

Ortiz, Michael V; Kobos, Rachel; Walsh, Michael; Slotkin, Emily K; Roberts, Stephen; Berger, Michael F; Hameed, Meera; Solit, David; Ladanyi, Marc; Shukla, Neerav; Kentsis, Alex.

Pediatr Blood Cancer ; 63(8): 1368-74, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27082517

12.

Pilot Study of Recurrent Ewing's Sarcoma Management with Vigil/Temozolomide/Irinotecan and Assessment of Circulating Tumor (ct) DNA.

Anderson, Peter; Ghisoli, Maurizio; Crompton, Brian D; Klega, Kelly S; Wexler, Leonard H; Slotkin, Emily K; Stanbery, Laura; Manning, Luisa; Wallraven, Gladice; Manley, Meghan; Horvath, Staci; Bognar, Ernest; Nemunaitis, John.

Clin Cancer Res ; 29(9): 1689-1697, 2023 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-36780200

13.

Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.

Pearson, Andrew D J; Federico, Sara; Gatz, Susanne A; Ortiz, Michael; Lesa, Giovanni; Scobie, Nicole; Gounaris, Ioannis; Weiner, Susan L; Weigel, Brenda; Unger, T J; Stewart, Elizabeth; Smith, Malcolm; Slotkin, Emily K; Reaman, Gregory; Pappo, Alberto; Nysom, Karsten; Norga, Koen; McDonough, Joe; Marshall, Lynley V; Ludwinski, Donna; Ligas, Franca; Karres, Dominik; Kool, Marcel; Horner, Thierry J; Henssen, Anton; Heenen, Delphine; Hawkins, Douglas S; Gore, Lia; Bender, Julia Glade; Galluzzo, Sara; Fox, Elizabeth; de Rojas, Teresa; Davies, Barry R; Chakrabarti, Jayeta; Carmichael, Juliet; Bradford, Diana; Blanc, Patricia; Bernardi, Ronald; Benchetrit, Sylvie; Akindele, Korede; Vassal, Gilles.

Eur J Cancer ; 190: 112950, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37441939

14.

Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma.

Kinnaman, Michael D; Zaccaria, Simone; Makohon-Moore, Alvin; Arnold, Brian; Levine, Max F; Gundem, Gunes; Arango Ossa, Juan E; Glodzik, Dominik; Rodríguez-Sánchez, M Irene; Bouvier, Nancy; Li, Shanita; Stockfisch, Emily; Dunigan, Marisa; Cobbs, Cassidy; Bhanot, Umesh K; You, Daoqi; Mullen, Katelyn; Melchor, Jerry P; Ortiz, Michael V; O'Donohue, Tara J; Slotkin, Emily K; Wexler, Leonard H; Dela Cruz, Filemon S; Hameed, Meera R; Glade Bender, Julia L; Tap, William D; Meyers, Paul A; Papaemmanuil, Elli; Kung, Andrew L; Iacobuzio-Donahue, Christine A.

Cancer Res ; 83(22): 3796-3812, 2023 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-37812025

15.

Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma.

D'Angelo, Sandra P; Richards, Allison L; Conley, Anthony P; Woo, Hyung Jun; Dickson, Mark A; Gounder, Mrinal; Kelly, Ciara; Keohan, Mary Louise; Movva, Sujana; Thornton, Katherine; Rosenbaum, Evan; Chi, Ping; Nacev, Benjamin; Chan, Jason E; Slotkin, Emily K; Kiesler, Hannah; Adamson, Travis; Ling, Lilan; Rao, Pavitra; Patel, Shreyaskumar; Livingston, Jonathan A; Singer, Samuel; Agaram, Narasimhan P; Antonescu, Cristina R; Koff, Andrew; Erinjeri, Joseph P; Hwang, Sinchun; Qin, Li-Xuan; Donoghue, Mark T A; Tap, William D.

Nat Commun ; 13(1): 3477, 2022 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-35710741

16.

Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.

Nacev, Benjamin A; Sanchez-Vega, Francisco; Smith, Shaleigh A; Antonescu, Cristina R; Rosenbaum, Evan; Shi, Hongyu; Tang, Cerise; Socci, Nicholas D; Rana, Satshil; Gularte-Mérida, Rodrigo; Zehir, Ahmet; Gounder, Mrinal M; Bowler, Timothy G; Luthra, Anisha; Jadeja, Bhumika; Okada, Azusa; Strong, Jonathan A; Stoller, Jake; Chan, Jason E; Chi, Ping; D'Angelo, Sandra P; Dickson, Mark A; Kelly, Ciara M; Keohan, Mary Louise; Movva, Sujana; Thornton, Katherine; Meyers, Paul A; Wexler, Leonard H; Slotkin, Emily K; Glade Bender, Julia L; Shukla, Neerav N; Hensley, Martee L; Healey, John H; La Quaglia, Michael P; Alektiar, Kaled M; Crago, Aimee M; Yoon, Sam S; Untch, Brian R; Chiang, Sarah; Agaram, Narasimhan P; Hameed, Meera R; Berger, Michael F; Solit, David B; Schultz, Nikolaus; Ladanyi, Marc; Singer, Samuel; Tap, William D.

Nat Commun ; 13(1): 3405, 2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35705560

17.

Phase 1 trial of olaratumab monotherapy and in combination with chemotherapy in pediatric patients with relapsed/refractory solid and central nervous system tumors.

Mascarenhas, Leo; Ogawa, Chitose; Laetsch, Theodore W; Weigel, Brenda J; Bishop, Michael W; Krystal, Julie; Borinstein, Scott C; Slotkin, Emily K; Muscal, Jodi A; Hingorani, Pooja; Levy, Donna E; Mo, Gary; Shahir, Ashwin; Wright, Jennifer; DuBois, Steven G.

Cancer Med ; 10(3): 843-856, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33474828

18.

Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.

Slotkin, Emily K; Bowman, Anita S; Levine, Max F; Dela Cruz, Filemon; Coutinho, Diego F; Sanchez, Glorymar I; Rosales, Nestor; Modak, Shakeel; Tap, William D; Gounder, Mrinal M; Thornton, Katherine A; Bouvier, Nancy; You, Daoqi; Gundem, Gunes; Gerstle, Justin T; Heaton, Todd E; LaQuaglia, Michael P; Wexler, Leonard H; Meyers, Paul A; Kung, Andrew L; Papaemmanuil, Elli; Zehir, Ahmet; Ladanyi, Marc; Shukla, Neerav.

Mol Cancer Res ; 19(7): 1146-1155, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33753552

19.

Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors.

Fiala, Elise M; Jayakumaran, Gowtham; Mauguen, Audrey; Kennedy, Jennifer A; Bouvier, Nancy; Kemel, Yelena; Fleischut, Megan Harlan; Maio, Anna; Salo-Mullen, Erin E; Sheehan, Margaret; Arnold, Angela G; Latham, Alicia; Carlo, Maria I; Cadoo, Karen; Murkherjee, Semanti; Slotkin, Emily K; Trippett, Tanya; Glade Bender, Julia; Meyers, Paul A; Wexler, Leonard; Dela Cruz, Filemon S; Cheung, Nai-Kong; Basu, Ellen; Kentsis, Alex; Ortiz, Michael; Francis, Jasmine H; Dunkel, Ira J; Khakoo, Yasmin; Gilheeney, Stephen; Farouk Sait, Sameer; Forlenza, Christopher J; Sulis, Maria; Karajannis, Matthias; Modak, Shakeel; Gerstle, Justin T; Heaton, Todd E; Roberts, Stephen; Yang, Ciyu; Jairam, Sowmya; Vijai, Joseph; Topka, Sabine; Friedman, Danielle N; Stadler, Zsofia K; Robson, Mark; Berger, Michael F; Schultz, Nikolaus; Ladanyi, Marc; O'Reilly, Richard J; Abramson, David H; Ceyhan-Birsoy, Ozge.

Nat Cancer ; 2: 357-365, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-34308366

20.

Genomic Determinants of Clinical Outcomes in Rhabdomyosarcoma.

Casey, Dana L; Wexler, Leonard H; Pitter, Kenneth L; Samstein, Robert M; Slotkin, Emily K; Wolden, Suzanne L.

Clin Cancer Res ; 26(5): 1135-1140, 2020 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-31699828

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