Detalhe da pesquisa
1.
BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice.
Blood
; 135(17): 1484-1496, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32078672
2.
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
N Engl J Med
; 369(24): 2313-23, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24304002
3.
Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A.
Blood
; 123(3): 317-25, 2014 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24227821
4.
Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients.
Blood
; 119(13): 3031-7, 2012 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223821
5.
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
Nat Med
; 13(4): 419-22, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17369837
6.
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.
Nat Med
; 12(3): 342-7, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16474400
7.
Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice.
Blood
; 114(13): 2802-11, 2009 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19654409
8.
Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.
Mol Ther
; 17(1): 144-52, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18941440
9.
Recombinant FIX Fc fusion protein activity assessment with the one-stage clotting assay: A multicenter, assessor-blinded, prospective study in Japan (J-Field Study).
Int J Lab Hematol
; 42(2): 162-169, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31820573
10.
Real-world assay variability between laboratories in monitoring of recombinant factor IX Fc fusion protein activity in plasma samples.
Int J Lab Hematol
; 42(3): 350-358, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202380
11.
Reproductive number of the COVID-19 epidemic in Switzerland with a focus on the Cantons of Basel-Stadt and Basel-Landschaft.
Swiss Med Wkly
; 150: w20271, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365217
12.
Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography.
J Virol Methods
; 140(1-2): 183-92, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17196264
13.
Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype.
Blood Coagul Fibrinolysis
; 28(7): 540-550, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28486277
14.
Recombinant Factor IX Fc Fusion Protein Maintains Full Procoagulant Properties and Exhibits Prolonged Efficacy in Hemophilia B Mice.
PLoS One
; 11(2): e0148255, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26840952
15.
Infectious titer assay for adeno-associated virus vectors with sensitivity sufficient to detect single infectious events.
Hum Gene Ther
; 15(7): 709-15, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15298029
16.
Recombinant adeno-associated virus: formulation challenges and strategies for a gene therapy vector.
Curr Opin Drug Discov Devel
; 6(2): 174-8, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12669452
17.
Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity.
Thromb Haemost
; 112(5): 932-40, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25144892
18.
A single chain variant of factor VIII Fc fusion protein retains normal in vivo efficacy but exhibits altered in vitro activity.
PLoS One
; 9(11): e113600, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415306
19.
Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice.
Blood
; 107(5): 1810-7, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16249376
20.
Inadvertent germline transmission of AAV2 vector: findings in a rabbit model correlate with those in a human clinical trial.
Mol Ther
; 13(6): 1064-73, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16631412