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Nat Prod Res ; : 1-8, 2023 Nov 02.
Artigo em Inglês | MEDLINE | ID: mdl-37915215

RESUMO

Different methods of purification and drying of sericin were evaluated to obtain a material free of contaminating residues through the development of safer and sustainable environmental technology. Samples purified using different proportions of alcohol solvents and by freezing/thawing were compared, while drying was performed by lyophilisation and atomisation in a spray. No significant statistical differences were observed in the yield of the purification process compared with the evaluated methods. Thus, the freezing/thawing method has economic and environmental advantages over other methods. Drying by spraying and lyophilisation produced particles exhibiting different properties in terms of structure: ß-sheets, random sheets, and ß-turns. In general, these particles are amorphous. The particles obtained by spray drying were more luminous, soluble, and spherical. Thus, purification by freezing/thawing and drying by spray can be considered appropriate methodologies for obtaining contaminant-free sericin through sustainable environmental technology.

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