Detalhe da pesquisa
1.
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes.
Nat Immunol
; 24(11): 1825-1838, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735593
2.
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.
Nat Immunol
; 24(7): 1188-1199, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322178
3.
Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.
Cell
; 173(7): 1796-1809.e17, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779944
4.
Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung.
Nat Immunol
; 21(2): 221-231, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959980
5.
Human microglia maturation is underpinned by specific gene regulatory networks.
Immunity
; 56(9): 2152-2171.e13, 2023 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37582369
6.
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1ß- and RNA-dependent co-activator of osteoclast gene expression.
Mol Cell
; 83(19): 3421-3437.e11, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751740
7.
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis.
Immunity
; 52(6): 1057-1074.e7, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32362324
8.
Environment drives selection and function of enhancers controlling tissue-specific macrophage identities.
Cell
; 159(6): 1327-40, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480297
9.
Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.
Immunity
; 51(4): 655-670.e8, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31587991
10.
NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids.
Cell
; 155(1): 200-214, 2013 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24074869
11.
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.
Cell
; 151(1): 138-52, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23021221
12.
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation.
Proc Natl Acad Sci U S A
; 121(2): e2316104121, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38165941
13.
Sterols and oxysterols in immune cell function.
Nat Immunol
; 14(9): 893-900, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23959186
14.
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Immunity
; 38(1): 106-18, 2013 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23273843
15.
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.
Mol Cell
; 51(3): 310-25, 2013 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23932714
16.
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.
Proc Natl Acad Sci U S A
; 115(20): E4680-E4689, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632203
17.
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.
Mol Cell
; 48(1): 28-38, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22921934
18.
Biomarkers of NAFLD progression: a lipidomics approach to an epidemic.
J Lipid Res
; 56(3): 722-736, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25598080
19.
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.
J Biol Chem
; 288(50): 35812-23, 2013 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189069
20.
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.
EMBO J
; 29(24): 4223-36, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21045807