Detalhe da pesquisa
1.
Roadmap on plasticity and epigenetics in cancer.
Phys Biol
; 19(3)2022 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35078159
2.
A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor.
J Pharmacokinet Pharmacodyn
; 47(2): 163-182, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32162138
3.
METLIN: A Technology Platform for Identifying Knowns and Unknowns.
Anal Chem
; 90(5): 3156-3164, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381867
4.
Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies.
Xenobiotica
; 47(7): 600-606, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27435693
5.
Determining conserved metabolic biomarkers from a million database queries.
Bioinformatics
; 31(23): 3721-4, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26275895
6.
Volumetric imaging of optically cleared and fluorescently labeled animal tissue (VIOLA) for quantifying the 3D biodistribution of nanoparticles at cellular resolution in tumor tissue.
J Control Release
; 354: 244-259, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36596340
7.
A whole-body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 671-683, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33793091
8.
Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195).
J Med Chem
; 64(1): 644-661, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356246
9.
Predicting Chemotherapy-Induced Neutropenia and Granulocyte Colony-Stimulating Factor Response Using Model-Based In Vitro to Clinical Translation.
AAPS J
; 22(6): 143, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33156437
10.
A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships.
AAPS J
; 22(2): 53, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32124093
11.
Kinetic modelling of [11C]flumazenil using data-driven methods.
Eur J Nucl Med Mol Imaging
; 36(4): 659-70, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19043703
12.
The runner's high: opioidergic mechanisms in the human brain.
Cereb Cortex
; 18(11): 2523-31, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18296435
13.
Applications of Quantitative Systems Pharmacology in Model-Informed Drug Discovery: Perspective on Impact and Opportunities.
CPT Pharmacometrics Syst Pharmacol
; 8(11): 777-791, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535440
14.
Metabolomics activity screening for identifying metabolites that modulate phenotype.
Nat Biotechnol
; 36(4): 316-320, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29621222
15.
Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape.
CPT Pharmacometrics Syst Pharmacol
; 7(3): 135-146, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29349875
16.
Found in Translation: Maximizing the Clinical Relevance of Nonclinical Oncology Studies.
Clin Cancer Res
; 23(4): 1080-1090, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27551002
17.
Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography.
Oncotarget
; 8(34): 57231-57245, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28915667
18.
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies.
Blood Adv
; 1(15): 1088-1100, 2017 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29296751
19.
Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio.
Am J Clin Nutr
; 84(1): 44-53, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16825680
20.
Automated identification of axonal growth cones in time-lapse image sequences.
J Neurosci Methods
; 151(2): 232-8, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16174535