Detalhe da pesquisa
1.
Leveraging in Vitro Models for Clinically Relevant Rare CYP2D6 Variants in Pharmacogenomics.
Drug Metab Dispos
; 52(3): 159-170, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167410
2.
Clinical pharmacology considerations for first-in-human clinical trials for enzyme replacement therapy.
J Inherit Metab Dis
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740427
3.
Clinical Relevance of the Constitutive Androstane Receptor.
Drug Metab Dispos
; 50(7): 1010-1018, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236665
4.
Research and Education Needs for Complex Generics.
Pharm Res
; 38(12): 1991-2001, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34950975
5.
The Roles of Xenobiotic Receptors: Beyond Chemical Disposition.
Drug Metab Dispos
; 46(9): 1361-1371, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29759961
6.
Creating a Roadmap to Quantitative Systems Pharmacology-Informed Rare Disease Drug Development: A Workshop Report.
Clin Pharmacol Ther
; 115(2): 201-205, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37984065
7.
Microphysiological Models for Mechanistic-Based Prediction of Idiosyncratic DILI.
Cells
; 12(11)2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296597
8.
Dexamethasone mitigates remdesivir-induced liver toxicity in human primary hepatocytes and COVID-19 patients.
Hepatol Commun
; 7(3): e0034, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36809346
9.
Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts.
Cancer Treat Rev
; 112: 102491, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36502615
10.
17α-Hydroxyprogesterone Caproate Inhibits Cytokine Production via Suppression of NF-κB Activation.
Front Pharmacol
; 13: 831315, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35330839
11.
Targeting CAR and Nrf2 improves cyclophosphamide bioactivation while reducing doxorubicin-induced cardiotoxicity in triple-negative breast cancer treatment.
JCI Insight
; 7(12)2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35579950