Pesquisa | BVS Violência e Saúde

1.

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.

Xiao, Haopeng; Bozi, Luiz H M; Sun, Yizhi; Riley, Christopher L; Philip, Vivek M; Chen, Mandy; Li, Jiaming; Zhang, Tian; Mills, Evanna L; Emont, Margo P; Sun, Wenfei; Reddy, Anita; Garrity, Ryan; Long, Jiani; Becher, Tobias; Vitas, Laura Potano; Laznik-Bogoslavski, Dina; Ordonez, Martha; Liu, Xinyue; Chen, Xiong; Wang, Yun; Liu, Weihai; Tran, Nhien; Liu, Yitong; Zhang, Yang; Cypess, Aaron M; White, Andrew P; He, Yuchen; Deng, Rebecca; Schöder, Heiko; Paulo, Joao A; Jedrychowski, Mark P; Banks, Alexander S; Tseng, Yu-Hua; Cohen, Paul; Tsai, Linus T; Rosen, Evan D; Klein, Samuel; Chondronikola, Maria; McAllister, Fiona E; Van Bruggen, Nick; Huttlin, Edward L; Spiegelman, Bruce M; Churchill, Gary A; Gygi, Steven P; Chouchani, Edward T.

Cell ; 185(24): 4654-4673.e28, 2022 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-36334589

2.

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.

Sveidahl Johansen, Olivia; Ma, Tao; Hansen, Jakob Bondo; Markussen, Lasse Kruse; Schreiber, Renate; Reverte-Salisa, Laia; Dong, Hua; Christensen, Dan Ploug; Sun, Wenfei; Gnad, Thorsten; Karavaeva, Iuliia; Nielsen, Thomas Svava; Kooijman, Sander; Cero, Cheryl; Dmytriyeva, Oksana; Shen, Yachen; Razzoli, Maria; O'Brien, Shannon L; Kuipers, Eline N; Nielsen, Carsten Haagen; Orchard, William; Willemsen, Nienke; Jespersen, Naja Zenius; Lundh, Morten; Sustarsic, Elahu Gosney; Hallgren, Cecilie Mørch; Frost, Mikkel; McGonigle, Seth; Isidor, Marie Sophie; Broholm, Christa; Pedersen, Oluf; Hansen, Jacob Bo; Grarup, Niels; Hansen, Torben; Kjær, Andreas; Granneman, James G; Babu, M Madan; Calebiro, Davide; Nielsen, Søren; Rydén, Mikael; Soccio, Raymond; Rensen, Patrick C N; Treebak, Jonas Thue; Schwartz, Thue Walter; Emanuelli, Brice; Bartolomucci, Alessandro; Pfeifer, Alexander; Zechner, Rudolf; Scheele, Camilla; Mandrup, Susanne.

Cell ; 184(13): 3502-3518.e33, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-34048700

3.

Alternative splicing of latrophilin-3 controls synapse formation.

Wang, Shuai; DeLeon, Chelsea; Sun, Wenfei; Quake, Stephen R; Roth, Bryan L; Südhof, Thomas C.

Nature ; 626(7997): 128-135, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38233523

4.

Spatial transcriptomics reveal neuron-astrocyte synergy in long-term memory.

Sun, Wenfei; Liu, Zhihui; Jiang, Xian; Chen, Michelle B; Dong, Hua; Liu, Jonathan; Südhof, Thomas C; Quake, Stephen R.

Nature ; 627(8003): 374-381, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38326616

5.

Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions.

Schönauer, Ria; Jin, Wenjun; Findeisen, Christin; Valenzuela, Irene; Devlin, Laura Alice; Murrell, Jill; Bedoukian, Emma C; Pöschla, Linda; Hantmann, Elena; Riedhammer, Korbinian M; Hoefele, Julia; Platzer, Konrad; Biemann, Ronald; Campeau, Philipp M; Münch, Johannes; Heyne, Henrike; Hoffmann, Anne; Ghosh, Adhideb; Sun, Wenfei; Dong, Hua; Noé, Falko; Wolfrum, Christian; Woods, Emily; Parker, Michael J; Neatu, Ruxandra; Le Guyader, Gwenael; Bruel, Ange-Line; Perrin, Laurence; Spiewak, Helena; Missotte, Isabelle; Fourgeaud, Melanie; Michaud, Vincent; Lacombe, Didier; Paolucci, Sarah A; Buchan, Jillian G; Glissmeyer, Margaret; Popp, Bernt; Blüher, Matthias; Sayer, John A; Halbritter, Jan.

Am J Hum Genet ; 110(6): 998-1007, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-37207645

6.

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis.

Sun, Wenfei; Dong, Hua; Balaz, Miroslav; Slyper, Michal; Drokhlyansky, Eugene; Colleluori, Georgia; Giordano, Antonio; Kovanicova, Zuzana; Stefanicka, Patrik; Balazova, Lucia; Ding, Lianggong; Husted, Anna Sofie; Rudofsky, Gottfried; Ukropec, Jozef; Cinti, Saverio; Schwartz, Thue W; Regev, Aviv; Wolfrum, Christian.

Nature ; 587(7832): 98-102, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-33116305

7.

Metabolic reconstitution of germ-free mice by a gnotobiotic microbiota varies over the circadian cycle.

Hoces, Daniel; Lan, Jiayi; Sun, Wenfei; Geiser, Tobias; Stäubli, Melanie L; Cappio Barazzone, Elisa; Arnoldini, Markus; Challa, Tenagne D; Klug, Manuel; Kellenberger, Alexandra; Nowok, Sven; Faccin, Erica; Macpherson, Andrew J; Stecher, Bärbel; Sunagawa, Shinichi; Zenobi, Renato; Hardt, Wolf-Dietrich; Wolfrum, Christian; Slack, Emma.

PLoS Biol ; 20(9): e3001743, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36126044

8.

The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.

Giroud, Maude; Kotschi, Stefan; Kwon, Yun; Le Thuc, Ophélia; Hoffmann, Anne; Gil-Lozano, Manuel; Karbiener, Michael; Higareda-Almaraz, Juan Carlos; Khani, Sajjad; Tews, Daniel; Fischer-Posovszky, Pamela; Sun, Wenfei; Dong, Hua; Ghosh, Adhideb; Wolfrum, Christian; Wabitsch, Martin; Virtanen, Kirsi A; Blüher, Matthias; Nielsen, Søren; Zeigerer, Anja; García-Cáceres, Cristina; Scheideler, Marcel; Herzig, Stephan; Bartelt, Alexander.

EMBO Rep ; 24(10): e57600, 2023 Oct 09.

Artigo em Inglês | MEDLINE | ID: mdl-37671834

9.

A stromal cell population that inhibits adipogenesis in mammalian fat depots.

Schwalie, Petra C; Dong, Hua; Zachara, Magda; Russeil, Julie; Alpern, Daniel; Akchiche, Nassila; Caprara, Christian; Sun, Wenfei; Schlaudraff, Kai-Uwe; Soldati, Gianni; Wolfrum, Christian; Deplancke, Bart.

Nature ; 559(7712): 103-108, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29925944

10.

Local acetate inhibits brown adipose tissue function.

Sun, Wenfei; Dong, Hua; Wolfrum, Christian.

Proc Natl Acad Sci U S A ; 118(49)2021 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-34845033

11.

A simple and sensitive ultra-high performance liquid chromatography tandem mass spectrometry method for the quantitative analysis of VX-548 in monkey plasma: Method validation and application to pharmacokinetic study.

Zhang, Huiying; Chen, Yonggang; Huang, Jing; Sun, Wenfei.

Biomed Chromatogr ; : e5907, 2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38783548

12.

Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue.

Meen, Astri J; Doncheva, Atanaska I; Böttcher, Yvonne; Dankel, Simon N; Hoffmann, Anne; Blüher, Matthias; Fernø, Johan; Mellgren, Gunnar; Ghosh, Adhideb; Sun, Wenfei; Dong, Hua; Noé, Falko; Wolfrum, Christian; Pejler, Gunnar; Dalen, Knut Tomas; Kolset, Svein O.

Int J Mol Sci ; 24(8)2023 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-37108048

13.

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.

Sarker, Gitalee; Sun, Wenfei; Rosenkranz, David; Pelczar, Pawel; Opitz, Lennart; Efthymiou, Vissarion; Wolfrum, Christian; Peleg-Raibstein, Daria.

Proc Natl Acad Sci U S A ; 116(21): 10547-10556, 2019 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-31061112

14.

Fat cells with a sweet tooth.

Sun, Wenfei; Wolfrum, Christian.

Nature ; 565(7738): 167-168, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30622347

15.

Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity.

Straub, Leon G; Efthymiou, Vissarion; Grandl, Gerald; Balaz, Miroslav; Challa, Tenagne Delessa; Truscello, Luca; Horvath, Carla; Moser, Caroline; Rachamin, Yael; Arnold, Myrtha; Sun, Wenfei; Modica, Salvatore; Wolfrum, Christian.

Diabetologia ; 62(11): 2094-2105, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31309261

16.

Genome assembly of Melilotus officinalis provides a new reference genome for functional genomics.

Meng, Aoran; Li, Xinru; Li, Zhiguang; Miao, Fuhong; Ma, Lichao; Li, Shuo; Sun, Wenfei; Huang, Jianwei; Yang, Guofeng.

BMC Genom Data ; 25(1): 37, 2024 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-38637749

17.

Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.

Reinisch, Isabel; Michenthaler, Helene; Sulaj, Alba; Moyschewitz, Elisabeth; Krstic, Jelena; Galhuber, Markus; Xu, Ruonan; Riahi, Zina; Wang, Tongtong; Vujic, Nemanja; Amor, Melina; Zenezini Chiozzi, Riccardo; Wabitsch, Martin; Kolb, Dagmar; Georgiadi, Anastasia; Glawitsch, Lisa; Heitzer, Ellen; Schulz, Tim J; Schupp, Michael; Sun, Wenfei; Dong, Hua; Ghosh, Adhideb; Hoffmann, Anne; Kratky, Dagmar; Hinte, Laura C; von Meyenn, Ferdinand; Heck, Albert J R; Blüher, Matthias; Herzig, Stephan; Wolfrum, Christian; Prokesch, Andreas.

Nat Commun ; 15(1): 1391, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38360943

18.

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice.

Long, Fen; Bhatti, Memoona R; Kellenberger, Alexandra; Sun, Wenfei; Modica, Salvatore; Höring, Marcus; Liebisch, Gerhard; Krieger, Jean-Philippe; Wolfrum, Christian; Challa, Tenagne D.

Mol Metab ; 69: 101675, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36682412

19.

Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits.

Hagemann, Tobias; Czechowski, Paul; Ghosh, Adhideb; Sun, Wenfei; Dong, Hua; Noé, Falko; Wolfrum, Christian; Blüher, Matthias; Hoffmann, Anne.

Biomedicines ; 11(10)2023 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-37893179

20.

Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots.

Palani, Nagendra P; Horvath, Carla; Timshel, Pascal N; Folkertsma, Pytrik; Grønning, Alexander G B; Henriksen, Tora I; Peijs, Lone; Jensen, Verena H; Sun, Wenfei; Jespersen, Naja Z; Wolfrum, Christian; Pers, Tune H; Nielsen, Søren; Scheele, Camilla.

Nat Metab ; 5(6): 996-1013, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37337126

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