Pesquisa | BVS Violência e Saúde

1.

The Nuclear Receptor PPARÎ³ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Daniel, Bence; Nagy, Gergely; Czimmerer, Zsolt; Horvath, Attila; Hammers, David W; Cuaranta-Monroy, Ixchelt; Poliska, Szilard; Tzerpos, Petros; Kolostyak, Zsuzsanna; Hays, Tristan T; Patsalos, Andreas; Houtman, René; Sauer, Sascha; Francois-Deleuze, Jean; Rastinejad, Fraydoon; Balint, Balint L; Sweeney, H Lee; Nagy, Laszlo.

Immunity ; 49(4): 615-626.e6, 2018 10 16.

Artigo em Inglês | MEDLINE | ID: mdl-30332629

2.

Myospreader improves gene editing in skeletal muscle by myonuclear propagation.

Poukalov, Kiril K; Valero, M Carmen; Muscato, Derek R; Adams, Leanne M; Chun, Heejae; Lee, Young Il; Andrade, Nadja S; Zeier, Zane; Sweeney, H Lee; Wang, Eric T.

Proc Natl Acad Sci U S A ; 121(19): e2321438121, 2024 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-38687782

3.

Myo10 tail is crucial for promoting long filopodia.

Chen, Xingxiang; Arciola, Jeffrey M; Lee, Young Il; Wong, Pak Hung Philip; Yin, Haoran; Tao, Quanqing; Jin, Yuqi; Qin, Xianan; Sweeney, H Lee; Park, Hyokeun.

J Biol Chem ; 300(1): 105523, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38043799

4.

Myosin VI rewrites the rules for myosin motors.

Sweeney, H Lee; Houdusse, Anne.

Cell ; 141(4): 573-82, 2010 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-20478251

5.

Myosin VI powers self-organization of branched contractile actin network.

Höök, Peter; Lee, Young Il; Sweeney, H Lee.

Biochem Biophys Res Commun ; 691: 149329, 2024 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-38042035

6.

Force Generation by Myosin Motors: A Structural Perspective.

Robert-Paganin, Julien; Pylypenko, Olena; Kikuti, Carlos; Sweeney, H Lee; Houdusse, Anne.

Chem Rev ; 120(1): 5-35, 2020 01 08.

Artigo em Inglês | MEDLINE | ID: mdl-31689091

7.

An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics.

Blanc, Florian; Isabet, Tatiana; Benisty, Hannah; Sweeney, H Lee; Cecchini, Marco; Houdusse, Anne.

Proc Natl Acad Sci U S A ; 115(24): 6213-6218, 2018 06 12.

Artigo em Inglês | MEDLINE | ID: mdl-29844196

8.

How Myosin Generates Force on Actin Filaments.

Houdusse, Anne; Sweeney, H Lee.

Trends Biochem Sci ; 41(12): 989-997, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27717739

9.

Activin type II receptor ligand signaling inhibition after experimental ischemic heart failure attenuates cardiac remodeling and prevents fibrosis.

Castillero, Estibaliz; Akashi, Hirokazu; Najjar, Marc; Ji, Ruiping; Brandstetter, Lea Maria; Wang, Catherine; Liao, Xianghai; Zhang, Xiaokan; Sperry, Alexandra; Gailes, Marcia; Guaman, Karina; Recht, Adam; Schlosberg, Ira; Sweeney, H Lee; Ali, Ziad A; Homma, Shunichi; Colombo, Paolo C; Ferrari, Giovanni; Schulze, P Christian; George, Isaac.

Am J Physiol Heart Circ Physiol ; 318(2): H378-H390, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31886717

10.

Simultaneous tracking of two motor domains reveals near simultaneous steps and stutter steps of myosin 10 on actin filament bundles.

Qin, Xianan; Yoo, Hanna; Man Cheng, Harry Chun; Nguyen, Quang Quan; Li, Jing; Liu, Xiaoyan; Prunetti, Laurence; Chen, Xingxiang; Liu, Teng; Sweeney, H Lee; Park, Hyokeun.

Biochem Biophys Res Commun ; 2020 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-32081426

11.

Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort.

Forbes, Sean C; Arora, Harneet; Willcocks, Rebecca J; Triplett, William T; Rooney, William D; Barnard, Alison M; Alabasi, Umar; Wang, Dah-Jyuu; Lott, Donovan J; Senesac, Claudia R; Harrington, Ann T; Finanger, Erika L; Tennekoon, Gihan I; Brandsema, John; Daniels, Michael J; Sweeney, H Lee; Walter, Glenn A; Vandenborne, Krista.

Radiology ; 295(3): 616-625, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32286193

12.

Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI.

Ménétrey, Julie; Isabet, Tatiana; Ropars, Virginie; Mukherjea, Monalisa; Pylypenko, Olena; Liu, Xiaoyan; Perez, Javier; Vachette, Patrice; Sweeney, H Lee; Houdusse, Anne M.

Mol Cell ; 48(1): 75-86, 2012 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-22940248

13.

Myosin Structures.

Sweeney, H Lee; Houdusse, Anne; Robert-Paganin, Julien.

Adv Exp Med Biol ; 1239: 7-19, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32451853

14.

[Pathophysiological Study on Thoracic Ascending Aorta of Mice with Myh11 ^R247C Heterozygous Mutation in Norepinephrine-induced Hypertension Model].

Yang, Yun; Wu, Zhou-Peng; Shu, Ye; Sweeney, H Lee; Huang, Bin.

Sichuan Da Xue Xue Bao Yi Xue Ban ; 51(2): 200-206, 2020 Mar.

Artigo em Zh | MEDLINE | ID: mdl-32220188

15.

Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin.

Barton, Elisabeth R; Pham, Jennifer; Brisson, Becky K; Park, SooHyun; Smith, Lucas R; Liu, Min; Tian, Zuozhen; Hammers, David W; Vassilakos, Georgios; Sweeney, H Lee.

Muscle Nerve ; 60(4): 464-473, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31323135

16.

Three-dimensional contractile muscle tissue consisting of human skeletal myocyte cell line.

Shima, Ai; Morimoto, Yuya; Sweeney, H Lee; Takeuchi, Shoji.

Exp Cell Res ; 370(1): 168-173, 2018 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-29928867

17.

Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities.

Chang, Audrey N; Mahajan, Pravin; Knapp, Stefan; Barton, Hannah; Sweeney, H Lee; Kamm, Kristine E; Stull, James T.

Proc Natl Acad Sci U S A ; 113(27): E3824-33, 2016 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-27325775

18.

Force-producing ADP state of myosin bound to actin.

Wulf, Sarah F; Ropars, Virginie; Fujita-Becker, Setsuko; Oster, Marco; Hofhaus, Goetz; Trabuco, Leonardo G; Pylypenko, Olena; Sweeney, H Lee; Houdusse, Anne M; Schröder, Rasmus R.

Proc Natl Acad Sci U S A ; 113(13): E1844-52, 2016 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-26976594

19.

Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

McDonald, Craig M; Campbell, Craig; Torricelli, Ricardo Erazo; Finkel, Richard S; Flanigan, Kevin M; Goemans, Nathalie; Heydemann, Peter; Kaminska, Anna; Kirschner, Janbernd; Muntoni, Francesco; Osorio, Andrés Nascimento; Schara, Ulrike; Sejersen, Thomas; Shieh, Perry B; Sweeney, H Lee; Topaloglu, Haluk; Tulinius, Már; Vilchez, Juan J; Voit, Thomas; Wong, Brenda; Elfring, Gary; Kroger, Hans; Luo, Xiaohui; McIntosh, Joseph; Ong, Tuyen; Riebling, Peter; Souza, Marcio; Spiegel, Robert J; Peltz, Stuart W; Mercuri, Eugenio.

Lancet ; 390(10101): 1489-1498, 2017 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-28728956

20.

Structural and functional cardiac profile after prolonged duration of mechanical unloading: potential implications for myocardial recovery.

Castillero, Estibaliz; Ali, Ziad A; Akashi, Hirokazu; Giangreco, Nicholas; Wang, Catherine; Stöhr, Eric J; Ji, Ruping; Zhang, Xiaokan; Kheysin, Nathaniel; Park, Joo-Eun S; Hegde, Sheetal; Patel, Sanatkumar; Stein, Samantha; Cuenca, Carlos; Leung, Diana; Homma, Shunichi; Tatonetti, Nicholas P; Topkara, Veli K; Takeda, Koji; Colombo, Paolo C; Naka, Yoshifumi; Sweeney, H Lee; Schulze, P Christian; George, Isaac.

Am J Physiol Heart Circ Physiol ; 315(5): H1463-H1476, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30141986

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