RESUMO
Eight new hydroperoxides and a new enone of germacrane-type sesquiterpenoids were isolated from the aerial parts of eight different samples of Eupatorium heterophyllum DC. (Asteraceae) collected in P. R. China. The structures were determined based on spectroscopic analyses. Seven of the eight samples produced hiyodorilactone A as a major constituent, while one afforded neither hiyodorilactone nor hydroperoxide. The results indicated the presence of diversity within this species.
Assuntos
Eupatorium/química , Peróxidos/análise , Componentes Aéreos da Planta/química , Extratos Vegetais/química , Sesquiterpenos de Germacrano/análise , China , Peróxidos/isolamento & purificação , Sesquiterpenos de Germacrano/isolamento & purificaçãoRESUMO
Chemical constituents and evolutionally neutral DNA sequences of six samples of Cremanthodium lineare Maxim., collected in the Sichuan Province of China, were studied. Three samples produced furanoeremophilanes and the other three, eremophilan-8-ones. The chemotypes were found to be correlated with DNA sequence types, suggesting that the chemical diversity observed has a genetic origin. Production of furanoeremophilanes by a Cremanthodium species suggests an evolutionary relationship between Cremanthodium and Ligularia species, and possibly to related genera.
Assuntos
Asteraceae/química , Asteraceae/genética , Medicamentos de Ervas Chinesas/isolamento & purificação , Sesquiterpenos/isolamento & purificação , Asteraceae/classificação , Sequência de Bases , Medicamentos de Ervas Chinesas/química , Medicamentos de Ervas Chinesas/classificação , Variação Genética , Estrutura Molecular , Ressonância Magnética Nuclear Biomolecular , Raízes de Plantas/química , Raízes de Plantas/genética , Análise de Sequência de DNA , Sesquiterpenos/químicaRESUMO
A thiophene, two furans, a dihydro furan, and two acetylenic benzene derivatives were isolated from the roots of Eupatorium heterophyllum collected in China. Structures were established on the basis of spectroscopic analyses as well as chemical transformations.