Detalhe da pesquisa
1.
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline.
Biochem Biophys Res Commun
; 513(2): 486-493, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975470
2.
A High Dose of Isoniazid Disturbs Endobiotic Homeostasis in Mouse Liver.
Drug Metab Dispos
; 44(11): 1742-1751, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27531952
3.
CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging.
Aging Cell
; 21(4): e13589, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263032
4.
CD38-NADase is a new major contributor to Duchenne muscular dystrophic phenotype.
EMBO Mol Med
; 14(5): e12860, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298089
5.
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Cell Rep
; 36(5): 109481, 2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34348145
6.
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Nat Metab
; 2(11): 1284-1304, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199925
7.
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.
Cell Metab
; 27(5): 1081-1095.e10, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29719225
8.
NAD and the aging process: Role in life, death and everything in between.
Mol Cell Endocrinol
; 455: 62-74, 2017 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27825999
9.
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
Cell Metab
; 23(6): 1127-1139, 2016 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27304511