Pesquisa | BVS Violência e Saúde

1.

In vivo activity of the dual PI3KÎ´ and PI3KÎ³ inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts.

Randall, Joanna; Evans, Kathryn; Watts, Ben; Smith, Christopher M; Hughes, Keira; Earley, Eric J; Erickson, Stephen W; Pachter, Jonathan A; Teicher, Beverly A; Smith, Malcolm A; Lock, Richard B.

Pediatr Blood Cancer ; 70(8): e30398, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37140091

2.

In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts.

Hughes, Keira; Evans, Kathryn; Earley, Eric J; Smith, Christopher M; Erickson, Stephen W; Stearns, Tim; Philip, Vivek M; Neuhauser, Steven B; Chuang, Jeffrey H; Jocoy, Emily L; Bult, Carol J; Teicher, Beverly A; Smith, Malcolm A; Lock, Richard B.

Pediatr Blood Cancer ; : e30503, 2023 Jun 20.

Artigo em Inglês | MEDLINE | ID: mdl-37339930

3.

In vivo evaluation of the lysine-specific demethylase (KDM1A/LSD1) inhibitor SP-2577 (Seclidemstat) against pediatric sarcoma preclinical models: A report from the Pediatric Preclinical Testing Consortium (PPTC).

Kurmasheva, Raushan T; Erickson, Stephen W; Han, Ruolan; Teicher, Beverly A; Smith, Malcolm A; Roth, Michael; Gorlick, Richard; Houghton, Peter J.

Pediatr Blood Cancer ; 68(11): e29304, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34453478

4.

Preclinical evaluation of the combination of AZD1775 and irinotecan against selected pediatric solid tumors: A Pediatric Preclinical Testing Consortium report.

Kolb, E Anders; Houghton, Peter J; Kurmasheva, Raushan T; Mosse, Yael P; Maris, John M; Erickson, Stephen W; Guo, Yuelong; Teicher, Beverly A; Smith, Malcolm A; Gorlick, Richard.

Pediatr Blood Cancer ; 67(5): e28098, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-31975571

5.

Antibody-drug conjugates for cancer therapy.

Thomas, Anish; Teicher, Beverly A; Hassan, Raffit.

Lancet Oncol ; 17(6): e254-e262, 2016 06.

Artigo em Inglês | MEDLINE | ID: mdl-27299281

6.

Antibody drug conjugates.

Teicher, Beverly A.

Curr Opin Oncol ; 26(5): 476-83, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25024051

7.

HTS384 NCI60: The Next Phase of the NCI60 Screen.

Kunkel, Mark W; Coussens, Nathan P; Morris, Joel; Taylor, Ronald C; Dexheimer, Thomas S; Jones, Eric M; Doroshow, James H; Teicher, Beverly A.

Cancer Res ; 2024 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-38861359

8.

In vivo activity of the second-generation proteasome inhibitor ixazomib against pediatric T-cell acute lymphoblastic leukemia xenografts.

Randall, Joanna; Evans, Kathryn; Watts, Ben; Kosasih, Hansen J; Smith, Christopher M; Earley, Eric J; Erickson, Stephen W; Jocoy, Emily L; Bult, Carol J; Teicher, Beverly A; de Bock, Charles E; Smith, Malcolm A; Lock, Richard B.

Exp Hematol ; 132: 104176, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38320689

9.

Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs.

Dexheimer, Thomas S; Coussens, Nathan P; Silvers, Thomas; Wright, John; Morris, Joel; Doroshow, James H; Teicher, Beverly A.

Cancer Res Commun ; 3(8): 1648-1661, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37637936

10.

Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.

Morris, Joel; Kunkel, Mark W; White, Stephen L; Wishka, Donn G; Lopez, Omar D; Bowles, Lori; Sellers Brady, Penny; Ramsey, Patricia; Grams, Julie; Rohrer, Tiffany; Martin, Karen; Dexheimer, Thomas S; Coussens, Nathan P; Evans, David; Risbood, Prabhakar; Sonkin, Dmitriy; Williams, John D; Polley, Eric C; Collins, Jerry M; Doroshow, James H; Teicher, Beverly A.

Mol Cancer Ther ; 22(11): 1270-1279, 2023 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-37550087

11.

Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.

Houghton, Peter J; Lock, Richard; Carol, Hernan; Morton, Christopher L; Gorlick, Richard; Anders Kolb, E; Keir, Stephen T; Reynolds, C Patrick; Kang, Min H; Maris, John M; Billups, Catherine A; Zhang, Mindy X; Madden, Stephen L; Teicher, Beverly A; Smith, Malcolm A.

Pediatr Blood Cancer ; 58(2): 200-9, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21548007

12.

Antibody-drug Conjugate Targets, Drugs, and Linkers.

Teicher, Beverly A; Morris, Joel.

Curr Cancer Drug Targets ; 22(6): 463-529, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35209819

13.

Trastuzumab Deruxtecan, Antibody-Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium.

Hingorani, Pooja; Zhang, Wendong; Zhang, Zhongting; Xu, Zhaohui; Wang, Wei-Lien; Roth, Michael E; Wang, Yifei; Gill, Jonathan B; Harrison, Douglas J; Teicher, Beverly A; Erickson, Stephen W; Gatto, Gregory; Kolb, Edward A; Smith, Malcolm A; Kurmasheva, Raushan T; Houghton, Peter J; Gorlick, Richard.

Mol Cancer Ther ; 21(8): 1318-1325, 2022 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-35657346

14.

Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.

Pongor, Lorinc S; Tlemsani, Camille; Elloumi, Fathi; Arakawa, Yasuhiro; Jo, Ukhyun; Gross, Jacob M; Mosavarpour, Sara; Varma, Sudhir; Kollipara, Rahul K; Roper, Nitin; Teicher, Beverly A; Aladjem, Mirit I; Reinhold, William; Thomas, Anish; Minna, John D; Johnson, Jane E; Pommier, Yves.

iScience ; 25(11): 105338, 2022 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-36325065

15.

Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.

Krytska, Kateryna; Casey, Colleen E; Pogoriler, Jennifer; Martinez, Daniel; Rathi, Komal S; Farrel, Alvin; Berko, Esther R; Tsang, Matthew; Sano, Renata R; Kendsersky, Nathan; Erickson, Stephen W; Teicher, Beverly A; Isse, Kumiko; Saunders, Laura; Smith, Malcolm A; Maris, John M; Mossé, Yael P.

Cancer Res Commun ; 2(7): 616-623, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-36381237

16.

Tumor endothelial marker 7 (TEM-7): a novel target for antiangiogenic therapy.

Bagley, Rebecca G; Rouleau, Cecile; Weber, William; Mehraein, Khodadad; Smale, Robert; Curiel, Maritza; Callahan, Michelle; Roy, Andre; Boutin, Paula; St Martin, Thia; Nacht, Mariana; Teicher, Beverly A.

Microvasc Res ; 82(3): 253-62, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21958527

17.

Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.

Byrne, Ann; McLaren, Rajashree P; Mason, Paul; Chai, Lilly; Dufault, Michael R; Huang, Yinyin; Liang, Beirong; Gans, Joseph D; Zhang, Mindy; Carter, Kara; Gladysheva, Tatiana B; Teicher, Beverly A; Biemann, Hans-Peter N; Booker, Michael; Goldberg, Mark A; Klinger, Katherine W; Lillie, James; Madden, Stephen L; Jiang, Yide.

Exp Cell Res ; 316(2): 258-71, 2010 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-19732767

18.

TGFß-Directed Therapeutics: 2020.

Teicher, Beverly A.

Pharmacol Ther ; 217: 107666, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-32835827

19.

Format (2D vs 3D) and media effect target expression and response of patient-derived and standard NSCLC lines to EGFR inhibitors.

Kaur, Gurmeet; Doroshow, James H; Teicher, Beverly A.

Cancer Treat Res Commun ; 29: 100463, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34601320

20.

Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine.

Kaur, Gurmeet; Evans, David M; Teicher, Beverly A; Coussens, Nathan P.

SLAS Discov ; 26(10): 1298-1314, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34772287

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