[Transcervical electro-resection of large polyps of the uterine cavity (author's transl)]. / Transzervikale Elektroresektion grosser Polypen des Corpus uteri. Kasuistischer Beitrag

A 65 year old hypertensive and diabetic patient who had several laparotomies and several unsuccessful curettages for vaginal bleeding was relieved of bleeding endometrial polyps with the aid of a 24 Charrier-Wolf electro-resectoscope for urological use.

[Treatment of bacterial vaginitis. Multicenter, randomized, open study with tinidazole in comparison with metronidazole]. / Behandlung der bakteriellen Vaginose. Multizentrische, randomisierte, offene Studie mit Tinidazol im Vergleich zu Metronidazol.

Seventy-five patients, aged between 18 and 55, with clinical bacterial vaginosis were assigned to two treatments in a randomized fashion. One group received a single oral dose of 2 g tinidazole, the other 2 x 1 vaginal tablet of metronidazole 400 mg on five consecutive days. The clinical success rate (healing and improvement) was 97% in the group treated with tinidazole, and 84% in the group treated with metronidazole. One patient of the tinidazole group and six patients of the metronidazole group had to be given further treatment because of an inadequate response to therapy. Although there were no statistically significant differences between the two groups with respect to clinical effect and tolerance, the results do show that, for the treatment of bacterial vaginosis, a single dose of tinidazole represents a clinically effective and well-tolerated therapy that is minimally stressful for the patient and is particularly suitable for prescription by the practicing physician.

[Laryngeal cancer and occupation--results of the Heidelberg laryngeal cancer study]. / Kehlkopfkarzinom und Berufstätigkeit--Ergebnisse der Heidelberger Kehlkopfkrebsstudie.

We conducted a case-control study of squamous cell carcinoma of the larynx referred to occupational factors in 164 patients compared with 656 controls adjusted for sex, age and area of residence, using a 1-to-4 matched design. Most of the cancer patients (92%) were blue collar workers. Only 8% of the cancer patients had attended technical college, college or university, compared with 31.3% of the control subjects. After adjustment for alcohol and tobacco consumption we found an increased relative risk of laryngeal cancer in subjects chronically exposed to cement dust, pine wood dust and coal-tar products. The risk associated with cement dust and coal-tar products was predominantly related to supraglottic cancer (RR = 1.88, CI = 0.8-4.3, RR = 6.11, CI = 1.7-21.6), respectively, after adjustment for tobacco and alcohol use. The risk associated with pine wood dust was related predominantly to glottic cancer (RR = 3.18, CI = 1.1-9.0) after adjustment for tobacco and alcohol use.