Pesquisa | BVS Violência e Saúde

1.

A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.

Magkouta, Sophia; Veroutis, Dimitris; Pousias, Athanasios; Papaspyropoulos, Angelos; Pippa, Natassa; Lougiakis, Nikolaos; Kambas, Konstantinos; Lagopati, Nefeli; Polyzou, Aikaterini; Georgiou, Maria; Chountoulesi, Maria; Pispas, Stergios; Foutadakis, Spyros; Pouli, Nicole; Marakos, Panagiotis; Kotsinas, Athanassios; Verginis, Panayotis; Valakos, Dimitrios; Mizi, Athanasia; Papantonis, Argyris; Vatsellas, Giannis; Galanos, Panagiotis; Bartek, Jiri; Petty, Russell; Serrano, Manuel; Thanos, Dimitris; Roussos, Charis; Demaria, Marco; Evangelou, Konstantinos; Gorgoulis, Vassilis G.

Mol Cell ; 83(19): 3558-3573.e7, 2023 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-37802028

2.

Stochastic responses are not left to pure "chance".

Banos, Aggelos; Agelopoulos, Marios; Thanos, Dimitris.

Cell ; 155(3): 499-502, 2013 Oct 24.

Artigo em Inglês | MEDLINE | ID: mdl-24243008

3.

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness.

Galani, Ioanna E; Triantafyllia, Vasiliki; Eleminiadou, Evridiki-Evangelia; Koltsida, Ourania; Stavropoulos, Athanasios; Manioudaki, Maria; Thanos, Dimitris; Doyle, Sean E; Kotenko, Sergei V; Thanopoulou, Kalliopi; Andreakos, Evangelos.

Immunity ; 46(5): 875-890.e6, 2017 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-28514692

4.

LifeTime and improving European healthcare through cell-based interceptive medicine.

Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A; Aerts, Stein; Amit, Ido; Bertero, Michela G; Bock, Christoph; Bredenoord, Annelien L; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; De Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernández, Xosé M; Figlerowicz, Marek; Gasser, Susan M; Hubner, Norbert; Kjems, Jørgen; Knoblich, Jürgen A; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean-Christophe; Marioni, John C; Marti-Renom, Marc A; Netea, Mihai G; Nickel, Dörthe; Nollmann, Marcelo; Novak, Halina R; Parkinson, Helen; Piccolo, Stefano; Pinheiro, Inês; Pombo, Ana; Popp, Christian; Reik, Wolf; Roman-Roman, Sergio; Rosenstiel, Philip; Schultze, Joachim L; Stegle, Oliver; Tanay, Amos; Testa, Giuseppe; Thanos, Dimitris; Theis, Fabian J; Torres-Padilla, Maria-Elena; Valencia, Alfonso; Vallot, Céline; van Oudenaarden, Alexander; Vidal, Marie; Voet, Thierry.

Nature ; 587(7834): 377-386, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32894860

5.

The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.

Nikopoulou, Chrysa; Panagopoulos, Giorgos; Sianidis, Georgios; Psarra, Eleni; Ford, Ethan; Thanos, Dimitris.

Mol Cell ; 71(2): 352-361.e5, 2018 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-30017585

6.

Identification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes.

Papathanasiou, Maria; Tsiftsoglou, Stefanos A; Polyzos, Alexander P; Papadopoulou, Deppie; Valakos, Dimitrios; Klagkou, Eleftheria; Karagianni, Panagiota; Pliatska, Maria; Talianidis, Iannis; Agelopoulos, Marios; Thanos, Dimitris.

EMBO J ; 40(1): e102236, 2021 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-33034061

7.

Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways.

Veroutis, Dimitris; Argyropoulou, Ourania D; Goules, Andreas V; Kambas, Konstantinos; Palamidas, Dimitris Anastasios; Evangelou, Konstantinos; Havaki, Sophia; Polyzou, Aikaterini; Valakos, Dimitrios; Xingi, Evangelia; Karatza, Elli; Boki, Kyriaki A; Cavazza, Alberto; Kittas, Christos; Thanos, Dimitris; Ricordi, Caterina; Marvisi, Chiara; Muratore, Francesco; Galli, Elena; Croci, Stefania; Salvarani, Carlo; Gorgoulis, Vassilis G; Tzioufas, Athanasios G.

Ann Rheum Dis ; 83(3): 342-350, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38050005

8.

Time's up: bursting out of transcription.

Ford, Ethan; Thanos, Dimitris.

Cell ; 138(3): 430-2, 2009 Aug 07.

Artigo em Inglês | MEDLINE | ID: mdl-19665966

9.

Pulsed Electromagnetic Fields (PEMFs) Trigger Cell Death and Senescence in Cancer Cells.

Pantelis, Pavlos; Theocharous, Giorgos; Veroutis, Dimitris; Vagena, Ioanna-Aglaia; Polyzou, Aikaterini; Thanos, Dimitris-Foivos; Kyrodimos, Efthymios; Kotsinas, Athanassios; Evangelou, Konstantinos; Lagopati, Nefeli; Gorgoulis, Vassilis G; Kotopoulos, Nicholas.

Int J Mol Sci ; 25(5)2024 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-38473720

10.

Virus Infection Induces NF-kappaB-dependent interchromosomal associations mediating monoallelic IFN-beta gene expression.

Apostolou, Effie; Thanos, Dimitris.

Cell ; 134(1): 85-96, 2008 Jul 11.

Artigo em Inglês | MEDLINE | ID: mdl-18614013

11.

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.

Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A; Aerts, Stein; Amit, Ido; Bertero, Michela G; Bock, Christoph; Bredenoord, Annelien L; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; De Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernández, Xosé M; Figlerowicz, Marek; Gasser, Susan M; Hubner, Norbert; Kjems, Jørgen; Knoblich, Jürgen A; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean-Christophe; Marioni, John C; Marti-Renom, Marc A; Netea, Mihai G; Nickel, Dörthe; Nollmann, Marcelo; Novak, Halina R; Parkinson, Helen; Piccolo, Stefano; Pinheiro, Inês; Pombo, Ana; Popp, Christian; Reik, Wolf; Roman-Roman, Sergio; Rosenstiel, Philip; Schultze, Joachim L; Stegle, Oliver; Tanay, Amos; Testa, Giuseppe; Thanos, Dimitris; Theis, Fabian J; Torres-Padilla, Maria-Elena; Valencia, Alfonso; Vallot, Céline; van Oudenaarden, Alexander; Vidal, Marie; Voet, Thierry.

Nature ; 592(7852): E8, 2021 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-33731935

12.

The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.

Nikopoulou, Chrysa; Panagopoulos, Giorgos; Sianidis, Georgios; Psarra, Eleni; Ford, Ethan; Thanos, Dimitris.

Mol Cell ; 74(2): 409-410, 2019 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-31002805

13.

Lessons learned and questions raised during and post-COVID-19 anthropopause period in relation to the environment and climate.

Zerefos, Christos S; Solomos, Stavros; Kapsomenakis, John; Poupkou, Anastasia; Dimitriadou, Lida; Polychroni, Iliana D; Kalabokas, Pavlos; Philandras, Constandinos M; Thanos, Dimitris.

Environ Dev Sustain ; 23(7): 10623-10645, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33230388

14.

Serum miRNA-based distinct clusters define three groups of breast cancer patients with different clinicopathological and immune characteristics.

Fortis, Sotirios P; Vaxevanis, Christoforos K; Mahaira, Louisa G; Sofopoulos, Michael; Sotiriadou, Nectaria N; Dinou, Amalia; Arnogiannaki, Niki; Stavropoulos-Giokas, Catherine; Thanos, Dimitris; Baxevanis, Constantin N; Perez, Sonia A.

Cancer Immunol Immunother ; 68(1): 57-70, 2019 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-30276443

15.

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

Matak, Andrija; Lahiri, Pooja; Ford, Ethan; Pabst, Daniela; Kashofer, Karl; Stellas, Dimitris; Thanos, Dimitris; Zatloukal, Kurt.

Hepatology ; 68(3): 933-948, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29171037

16.

Transcriptomics in tissue glucocorticoid sensitivity.

Nicolaides, Nicolas C; Polyzos, Alexandros; Koniari, Eleni; Lamprokostopoulou, Agaristi; Papageorgiou, Ifigeneia; Golfinopoulou, Eleni; Papathanasiou, Chrysanthi; Sertedaki, Amalia; Thanos, Dimitris; Chrousos, George P; Charmandari, Evangelia.

Eur J Clin Invest ; 49(8): e13129, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31091335

17.

The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.

Nanou, Aikaterini; Toumpeki, Chrisavgi; Lavigne, Matthieu D; Lazou, Vassiliki; Demmers, Jeroen; Paparountas, Triantafillos; Thanos, Dimitris; Katsantoni, Eleni.

Nucleic Acids Res ; 45(1): 142-154, 2017 01 09.

Artigo em Inglês | MEDLINE | ID: mdl-27651463

18.

Impaired anti-inflammatory activity of PPARÎ³ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation.

Vakrakou, Aigli G; Polyzos, Alexandros; Kapsogeorgou, Efstathia K; Thanos, Dimitris; Manoussakis, Menelaos N.

J Autoimmun ; 86: 62-74, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29033144

19.

Exploring and exploiting the systemic effects of deregulated replication licensing.

Petrakis, Theodoros G; Komseli, Eirini-Stavroula; Papaioannou, Marilena; Vougas, Kostas; Polyzos, Alexandros; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Trougakos, Ioannis P; Thanos, Dimitris; Branzei, Dana; Townsend, Paul; Gorgoulis, Vassilis G.

Semin Cancer Biol ; 37-38: 3-15, 2016 06.

Artigo em Inglês | MEDLINE | ID: mdl-26707000

20.

Transcription Factor Ets-2 Acts as a Preinduction Repressor of Interleukin-2 (IL-2) Transcription in Naive T Helper Lymphocytes.

Panagoulias, Ioannis; Georgakopoulos, Tassos; Aggeletopoulou, Ioanna; Agelopoulos, Marios; Thanos, Dimitris; Mouzaki, Athanasia.

J Biol Chem ; 291(52): 26707-26721, 2016 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-27815505

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A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.

Stochastic responses are not left to pure "chance".

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness.

LifeTime and improving European healthcare through cell-based interceptive medicine.

The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.

Identification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes.

Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways.

Time's up: bursting out of transcription.

Pulsed Electromagnetic Fields (PEMFs) Trigger Cell Death and Senescence in Cancer Cells.

Virus Infection Induces NF-kappaB-dependent interchromosomal associations mediating monoallelic IFN-beta gene expression.

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.

The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.

Lessons learned and questions raised during and post-COVID-19 anthropopause period in relation to the environment and climate.

Serum miRNA-based distinct clusters define three groups of breast cancer patients with different clinicopathological and immune characteristics.

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

Transcriptomics in tissue glucocorticoid sensitivity.

The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.

Impaired anti-inflammatory activity of PPARÎ³ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation.

Exploring and exploiting the systemic effects of deregulated replication licensing.

Transcription Factor Ets-2 Acts as a Preinduction Repressor of Interleukin-2 (IL-2) Transcription in Naive T Helper Lymphocytes.