Detalhe da pesquisa
1.
IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.
J Proteome Res
; 22(4): 1309-1321, 2023 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36888912
2.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Brain
; 142(10): 3243-3264, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504240
3.
CSF p-tau increase in response to Aß-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles.
Acta Neuropathol
; 143(2): 287-290, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34961894
4.
Phosphorylation of protein Tau by GSK3ß prolongs survival of bigenic Tau.P301L×GSK3ß mice by delaying brainstem tauopathy.
Neurobiol Dis
; 67: 119-32, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24704314
5.
Development and Characterization of Mouse-Specific Anti-Tau Monoclonal Antibodies: Relevance for Analysis of Murine Tau in Cerebrospinal Fluid.
J Alzheimers Dis
; 93(1): 151-167, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36970909
6.
Anti-tau intrabodies: From anti-tau immunoglobulins to the development of functional scFv intrabodies.
Mol Ther Methods Clin Dev
; 31: 101158, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38074413
7.
Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice.
FASEB J
; 25(9): 3208-18, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593432
8.
Development and validation of a high-sensitivity assay for measuring p217+tau in plasma.
Alzheimers Dement (Amst)
; 13(1): e12204, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34095436
9.
Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.
J Chromatogr A
; 1651: 462299, 2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34107398
10.
Development and Validation of a High Sensitivity Assay for Measuring p217â+âtau in Cerebrospinal Fluid.
J Alzheimers Dis
; 77(4): 1417-1430, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32831201
11.
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease.
Nat Commun
; 11(1): 1683, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32246036
12.
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
J Alzheimers Dis
; 77(4): 1397-1416, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32894244
13.
Neural oscillations during cognitive processes in an App knock-in mouse model of Alzheimer's disease pathology.
Sci Rep
; 9(1): 16363, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31705038
14.
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
J Alzheimers Dis
; 65(1): 265-281, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30040731
15.
Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope.
J Alzheimers Dis
; 56(2): 585-599, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28035925
16.
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.
PLoS One
; 8(12): e84442, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24376810
17.
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy.
PLoS One
; 8(8): e72301, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977276
18.
Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease.
Int J Alzheimers Dis
; 2012: 251426, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22720188