Detalhe da pesquisa
1.
Machine Learning Models Identify Inhibitors of New Delhi Metallo-ß-lactamase.
J Chem Inf Model
; 64(10): 3977-3991, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38727192
2.
Visualizing the Dynamic Metalation State of New Delhi Metallo-ß-lactamase-1 in Bacteria Using a Reversible Fluorescent Probe.
J Am Chem Soc
; 143(22): 8314-8323, 2021 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038127
3.
Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468463
4.
A Lysine-Targeted Affinity Label for Serine-ß-Lactamase Also Covalently Modifies New Delhi Metallo-ß-lactamase-1 (NDM-1).
Biochemistry
; 58(25): 2834-2843, 2019 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31145588
5.
Evolution of New Delhi metallo-ß-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity.
J Biol Chem
; 293(32): 12606-12618, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29909397
6.
Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity.
Biochemistry
; 54(28): 4342-53, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26115006
7.
Covalent inhibition of New Delhi metallo-ß-lactamase-1 (NDM-1) by cefaclor.
Chembiochem
; 15(17): 2541-8, 2014 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25302694
8.
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.
Biochemistry
; 52(9): 1603-10, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23387521
9.
An altered zinc-binding site confers resistance to a covalent inactivator of New Delhi metallo-beta-lactamase-1 (NDM-1) discovered by high-throughput screening.
Bioorg Med Chem
; 21(11): 3138-46, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23591260
10.
Structural insights into the design of reversible fluorescent probes for metallo-ß-lactamases NDM-1, VIM-2, and IMP-1.
J Inorg Biochem
; 233: 111869, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653820
11.
Discovery of an Effective Small-Molecule Allosteric Inhibitor of New Delhi Metallo-ß-lactamase (NDM).
ACS Infect Dis
; 8(4): 811-824, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353502
12.
Characterization of purified New Delhi metallo-ß-lactamase-1.
Biochemistry
; 50(46): 10102-13, 2011 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22029287
13.
Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-γ-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site.
ACS Omega
; 6(21): 13567-13578, 2021 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34095651
14.
Metal displacement and stoichiometry of protein-metal complexes under native conditions using capillary electrophoresis/mass spectrometry.
Rapid Commun Mass Spectrom
; 24(18): 2730-4, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20814979
15.
Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-ß-lactamase Inhibitor Development.
ChemMedChem
; 15(14): 1272-1282, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315115
16.
Elusive structural changes of New Delhi metallo-ß-lactamase revealed by ultraviolet photodissociation mass spectrometry.
Chem Sci
; 11(33): 8999-9010, 2020 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34123154
17.
Arabidopsis thaliana mitochondrial glyoxalase 2-1 exhibits beta-lactamase activity.
Biochemistry
; 48(36): 8491-3, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19735113
18.
Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-ß-Lactamases.
ChemMedChem
; 14(13): 1271-1282, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31124602
19.
A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
mBio
; 10(6)2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31744917
20.
Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.
Biochemistry
; 47(29): 7706-14, 2008 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18627129