1.
Bioorg Med Chem Lett
; 21(16): 4768-72, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21767951
RESUMO
Promising synthetic derivatives of macrolactone natural product (-)-A26771B have been designed and synthesized both from semisynthesis and total synthesis. Further optimization led to the first synthesis of macrolactam analogs of (-)-A26771B with improved antibacterial activity and metabolic stability.