RESUMO
The current study aimed to present the neuroradiological and histopathological features of intracranial hemangioendothelioma (HE). The computed tomography (CT; n=3) and magnetic resonance imaging (MRI; n=7) features, and the clinical presentations of 7 patients with pathologically documented HEs were retrospectively analyzed. Lesions were observed in the right side of the skull (the frontal bone in 1 patient and the parietal bone in 1 patient), the tentorium (2 patients), the cerebral falx (1 patient), the right cavernous sinus (1 patient) and the right temporal lobe (1 patient). The tumor was lobulated in 5 cases and round in 2 cases. The majority of tumors appeared isointense or hypointense with multiple scattered hyperintensities on T1-weighted MRI. Moreover, the lesions appeared as inhomogeneous hyperintense regions with multiple enlarged and tortuous blood flow voids on T2-weighted MRI. The lesions also showed marked gadolinium enhancement in a honeycomb pattern. CT scan results showed a isoattenuation region (32-47 HU), with numerous small, round, high-density foci. The 2 cases with skull lesions presented with local bone destruction and discontinuous bone lines of the tabula interna ossis cranii. In 1 case, MR angiography revealed abnormal vessels in the basilar region. A total of 4 cases were epithelial HE, 2 were retiform HE and 1 was kaposiform HE. Histological examination revealed endothelial cell proliferation with vascular lesions and a mucous matrix or dense fibrous mesenchyme. In conclusion, intracranial HE is rare, but should be considered in the differential diagnosis when evaluating intracranial neoplasms. A well-defined lobulated mass and imaging features that include internal heterogeneity, small scattered hemorrhages and thromboses, signal voids of vessels, and marked and delayed enhancement may confirm the diagnosis of HE.
RESUMO
In this study, fifty healthy normal volunteers were divided into 3 groups according to age: group A (15-30 years, n=14), group B (31-50 years, n=24), group C (>51 years, n=12). The FA and ADC values in PZ and CZ were measured, and difference between the PZ and CZ were assessed. The results indicated that no significant difference were found in the FA and ADC values between the left and right of PZ (P>0.05), but significant differences were observed in the FA and ADC values between PZ and CZ within each group (P<0.05). The FA values of PZ in three groups were 0.227±0.052, 0.202±0.055, and 0.145±0.034, respectively. The ADC values were found to be 1.439±0.160×10(-3), 1.652±0.256×10(-3), and 2.001±0.266×10(-3) mm(2)/s, accordingly. The FA and ADC values in PZ were significantly (P<0.05) different between groups. The FA values of CZ in different groups were found to be 0.291±0.083, 0.287±0.045, and 0.257±0.059, respectively; while the corresponding ADC values were 1.374±0.171×10(-3), 1.382±0.178×10(-3), and 1.415±0.136×10(-3) mm(2)/s, respectively. The FA and ADC values in CZ were not statistically (P>0.05) different between groups. Pearson correlation analysis results showedthat the FA values in PZ havenegative correlation with age (r=-0.498, P<0.05), while the ADC values exhibited a positive correlation with age (r=0.682, P<0.05). No correlations between the changes of FA and ADC values and age were noted in CZ. In conclusion, the FA and ADC values in the normal prostatic PZ were age-dependent. FA decreases and ADC increases with age. In contrast, the FA and ADC values in the normal prostatic CZ were not significantly age-related.