Pesquisa | BVS Violência e Saúde

1.

Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network.

Martínez-Riaño, Ana; Wang, Shenshen; Boeing, Stefan; Minoughan, Sophie; Casal, Antonio; Spillane, Katelyn M; Ludewig, Burkhard; Tolar, Pavel.

Nat Immunol ; 24(8): 1281-1294, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37443283

2.

Author Correction: Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network.

Martínez-Riaño, Ana; Wang, Shenshen; Boeing, Stefan; Minoughan, Sophie; Casal, Antonio; Spillane, Katelyn M; Ludewig, Burkhard; Tolar, Pavel.

Nat Immunol ; 24(12): 2164, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37863990

3.

Chronic calcium signaling in IgE⁺ B cells limits plasma cell differentiation and survival.

Newman, Rebecca; Tolar, Pavel.

Immunity ; 54(12): 2756-2771.e10, 2021 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-34879220

4.

Germinal center B cells recognize antigen through a specialized immune synapse architecture.

Nowosad, Carla R; Spillane, Katelyn M; Tolar, Pavel.

Nat Immunol ; 17(7): 870-7, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27183103

5.

Monocytes work harder under pressure.

Tolar, Pavel; Wack, Andreas.

Nat Immunol ; 20(11): 1422-1424, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31595058

6.

Pathogenic ACVR1^R206H activation by Activin A-induced receptor clustering and autophosphorylation.

Ramachandran, Anassuya; Mehic, Merima; Wasim, Laabiah; Malinova, Dessislava; Gori, Ilaria; Blaszczyk, Beata K; Carvalho, Diana M; Shore, Eileen M; Jones, Chris; Hyvönen, Marko; Tolar, Pavel; Hill, Caroline S.

EMBO J ; 40(14): e106317, 2021 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-34003511

7.

Endophilin A2 regulates B-cell endocytosis and is required for germinal center and humoral responses.

Malinova, Dessislava; Wasim, Laabiah; Newman, Rebecca; Martínez-Riaño, Ana; Engels, Niklas; Tolar, Pavel.

EMBO Rep ; 22(9): e51328, 2021 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-34323351

8.

Digital holography-based 3D particle localization for single-molecule tweezer techniques.

Flewellen, James L; Minoughan, Sophie; Garcia, Isabel Llorente; Tolar, Pavel.

Biophys J ; 121(13): 2538-2549, 2022 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-35659644

9.

MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells.

Merkenschlager, Julia; Eksmond, Urszula; Danelli, Luca; Attig, Jan; Young, George R; Nowosad, Carla; Tolar, Pavel; Kassiotis, George.

Blood ; 133(10): 1108-1118, 2019 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-30700420

10.

Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling.

Liu, Wanli; Meckel, Tobias; Tolar, Pavel; Sohn, Hae Won; Pierce, Susan K.

Immunity ; 32(6): 778-89, 2010 Jun 25.

Artigo em Inglês | MEDLINE | ID: mdl-20620943

11.

The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

Tolar, Pavel; Hanna, Joseph; Krueger, Peter D; Pierce, Susan K.

Immunity ; 30(1): 44-55, 2009 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-19135393

12.

Molecular Mechanisms of B Cell Antigen Gathering and Endocytosis.

Hoogeboom, Robbert; Tolar, Pavel.

Curr Top Microbiol Immunol ; 393: 45-63, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-26336965

13.

Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.

Satpathy, Shankha; Wagner, Sebastian A; Beli, Petra; Gupta, Rajat; Kristiansen, Trine A; Malinova, Dessislava; Francavilla, Chiara; Tolar, Pavel; Bishop, Gail A; Hostager, Bruce S; Choudhary, Chunaram.

Mol Syst Biol ; 11(6): 810, 2015 Jun 02.

Artigo em Inglês | MEDLINE | ID: mdl-26038114

14.

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.

Davis, R Eric; Ngo, Vu N; Lenz, Georg; Tolar, Pavel; Young, Ryan M; Romesser, Paul B; Kohlhammer, Holger; Lamy, Laurence; Zhao, Hong; Yang, Yandan; Xu, Weihong; Shaffer, Arthur L; Wright, George; Xiao, Wenming; Powell, John; Jiang, Jian-Kang; Thomas, Craig J; Rosenwald, Andreas; Ott, German; Muller-Hermelink, Hans Konrad; Gascoyne, Randy D; Connors, Joseph M; Johnson, Nathalie A; Rimsza, Lisa M; Campo, Elias; Jaffe, Elaine S; Wilson, Wyndham H; Delabie, Jan; Smeland, Erlend B; Fisher, Richard I; Braziel, Rita M; Tubbs, Raymond R; Cook, J R; Weisenburger, Dennis D; Chan, Wing C; Pierce, Susan K; Staudt, Louis M.

Nature ; 463(7277): 88-92, 2010 Jan 07.

Artigo em Inglês | MEDLINE | ID: mdl-20054396

15.

Regulation of BCR-mediated Ca²⁺ mobilization by MIZ1-TMBIM4 safeguards IgG1⁺ GC B cell-positive selection.

Zhang, Lingling; Toboso-Navasa, Amparo; Gunawan, Arief; Camara, Abdouramane; Nakagawa, Rinako; Finsterbusch, Katja; Chakravarty, Probir; Newman, Rebecca; Zhang, Yang; Eilers, Martin; Wack, Andreas; Tolar, Pavel; Toellner, Kai-Michael; Calado, Dinis Pedro.

Sci Immunol ; 9(94): eadk0092, 2024 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-38579014

16.

The molecular assembly and organization of signaling active B-cell receptor oligomers.

Tolar, Pavel; Sohn, Hae Won; Liu, Wanli; Pierce, Susan K.

Immunol Rev ; 232(1): 34-41, 2009 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-19909354

17.

Structural basis for Fc receptor recognition of immunoglobulin M.

Chen, Qu; Menon, Rajesh P; Masino, Laura; Tolar, Pavel; Rosenthal, Peter B.

Nat Struct Mol Biol ; 30(7): 1033-1039, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37095205

18.

Antigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.

Liu, Wanli; Won Sohn, Hae; Tolar, Pavel; Meckel, Tobias; Pierce, Susan K.

J Immunol ; 184(4): 1977-89, 2010 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-20083655

19.

Viewing the antigen-induced initiation of B-cell activation in living cells.

Tolar, Pavel; Sohn, Hae Won; Pierce, Susan K.

Immunol Rev ; 221: 64-76, 2008 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-18275475

20.

Unveiling the B cell receptor structure.

Tolar, Pavel; Pierce, Susan K.

Science ; 377(6608): 819-820, 2022 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-35981020

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