Detalhe da pesquisa
1.
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Arch Pharm (Weinheim)
; 357(3): e2300583, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110703
2.
A novel smaller ß-defensin-derived peptide is active against multidrug-resistant bacterial strains.
FASEB J
; 35(12): e22026, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818435
3.
Tailoring the Structure of Cell Penetrating DNA and RNA Binding Nucleopeptides.
Int J Mol Sci
; 23(15)2022 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955638
4.
Click-Chemistry (CuAAC) Trimerization of an αv ß6 Integrin Targeting Ga-68-Peptide: Enhanced Contrast for in-Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts.
Chembiochem
; 21(19): 2836-2843, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32359011
5.
Disulfide Bond Replacement with 1,4- and 1,5-Disubstituted [1,2,3]-Triazole on C-X-C Chemokine Receptor Type 4 (CXCR4) Peptide Ligands: Small Changes that Make Big Differences.
Chemistry
; 26(44): 10113-10125, 2020 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32603023
6.
Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells.
Molecules
; 25(14)2020 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32650558
7.
Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers.
Bioorg Med Chem
; 26(9): 2539-2550, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29656988
8.
From a Helix to a Small Cycle: Metadynamics-Inspired αvß6 Integrin Selective Ligands.
Angew Chem Int Ed Engl
; 57(44): 14645-14649, 2018 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29660806
9.
Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34.
Angew Chem Int Ed Engl
; 56(28): 8153-8157, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28544137
10.
Switchable Protecting Strategy for Solid Phase Synthesis of DNA and RNA Interacting Nucleopeptides.
J Org Chem
; 81(23): 11612-11625, 2016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791366
11.
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity.
J Med Chem
; 67(3): 1843-1860, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253001
12.
Paper-based electrochemical device for early detection of integrin αvß6 expressing tumors.
Commun Chem
; 7(1): 60, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514757
13.
Ultrasound-assisted Peptide Nucleic Acids synthesis (US-PNAS).
Ultrason Sonochem
; 95: 106360, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36913782
14.
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells.
Eur J Med Chem
; 247: 115022, 2023 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36549114
15.
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.
J Med Chem
; 66(10): 6591-6616, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155735
16.
Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.
Cell Chem Biol
; 30(12): 1652-1665.e6, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065101
17.
Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions.
PLoS One
; 17(6): e0267651, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35731722
18.
CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.
J Med Chem
; 65(5): 4007-4017, 2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188390
19.
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.
Eur J Med Chem
; 237: 114410, 2022 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35525212
20.
Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders.
J Med Chem
; 64(16): 11774-11797, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34351144