Prevalence of hysterectomy and associated factors in Brazilian women aged 50 and older: findings from the Brazilian Longitudinal Study of Ageing (ELSI-Brazil).

BACKGROUND: Hysterectomy is a gynaecological surgical procedure in which the uterus is removed as a treatment for both malignant and benign gynaecological diseases. A hysterectomy is also performed to minimise risks in women with problems related to the uterus. This study aimed to estimate the prevalence of reported hysterectomy and associated risk factors in Brazilian women aged 50 and older. METHODS: A cross-sectional study using data from the Brazilian Longitudinal Study of Ageing (ELSI-Brazil) was conducted. A total of 5,293 women aged 50 and over who participated in the ELSI-Brazil study in 2015 and 2016 were included. The prevalence rate of hysterectomy was estimated and the main reasons for performing the surgery were identified. The bivariate analyses utilised the chi-square test, while multivariate analyses employed Poisson regression with a robust estimator. RESULTS: The reported prevalence of hysterectomy was 17.8%. The most prevalent reason for the surgery was the presence of uterine myoma. Significant and independent associations were observed in women aged 63 and older, married, having undergone preventive exams, hormonal treatment, had up to three deliveries and having a private health plan. CONCLUSION: The main objective of the study was achieved. The prevalence of hysterectomy in Brazilian women aged 50 and older was 17.8%. Significant associations were observed with participants' sociodemographic and clinical characteristics reinforcing the importance of considering the reproductive characteristics of women as indicators of health status.

What is the impact of national public expenditure and its allocation on neonatal and child mortality? A machine learning analysis.

BACKGROUND: Understanding the impact of national public expenditure and its allocation on child mortality may help governments move towards target 3.2 proposed in the 2030 Agenda. The objective of this study was to estimate the impacts of governmental expenditures, total, on health, and on other sectors, on neonatal mortality and mortality of children aged between 28 days and five years. METHODS: This study has an ecological design with a population of 147 countries, with data between 2012 and 2019. Two steps were used: first, the Generalized Propensity Score of public spending was calculated; afterward, the Generalized Propensity Score was used to estimate the expenditures' association with mortality rates. The primary outcomes were neonatal mortality rates (NeoRt) and mortality rates in children between 28 days and 5 years (NeoU5Rt). RESULTS: The 1% variation in Int$ Purchasing Power Parity (Int$ PPP) per capita in total public expenditures, expenditure in health, and in other sectors were associated with a variation of -0.635 (95% CI -1.176, -0.095), -2.17 (95% CI -3.051, -1.289) -0.632 (95% CI -1.169, -0.095) in NeoRt, respectively The same variation in public expenditures in sectors other than health, was associates with a variation of -1.772 (95% CI -6.219, -1.459) on NeoU5Rt. The results regarding the impact of total and health public spending on NeoU5Rt were not consistent. CONCLUSION: Public investments impact mortality in children under 5 years of age. Likely, the allocation of expenditures between the health sector and the other social sectors will have different impacts on mortality between the NeoRt and the NeoU5Rt.

Effects of the application of a food processing-based classification system in obese women: A randomized controlled pilot study.

Background: Obesity is one of the major public health problems worldwide and contributes to the onset of many diseases, especially the ones related to the metabolic syndrome. The new Dietary Guidelines for the Brazilian population bring a new food classification based on food processing and prioritizes the consumption of fresh or minimally processed foods. Aim: This study analyzed the effects of an educational intervention on obese women, on their weight loss, quality of life, components of the metabolic syndrome and pain. Methods: Randomized controlled pilot study, including 40 obese women, randomized into 2 groups: control group and intervention group. An educational intervention with 5 biweekly meetings of 90 min based on the Dietary Guidelines for the Brazilian population (2014) was carried out involving the intervention group. Parameters related to weight loss, quality of life (SF-36), pain (McGill), bioelectrical impedance analysis, cardiorespiratory fitness, and serum and clinical components of metabolic syndrome, as well as serum concentrations of cytokines were assessed. Results: Significantly decrease of body mass, waist and hip circumferences, basal metabolic rate, extracellular water, body capacitance, and body cell mass were observed in the intervention group after 3 months. Reduction of pain and improvement in quality of life and cardiorespiratory fitness were also observed in the intervention group. There were reductions in waist circumference and glycemia, components of metabolic syndrome. Conclusions: This study showed that the educational intervention can be associated with weight loss, increase in quality of life, reduction of pain, and better metabolic syndrome parameters in obese women.

Relevance of the first thousand days of life to the development of wheezing in children aged 6-7 years.

INTRODUCTION: The first thousand days of life are a critical stage for the development of respiratory and immune systems. Many events in this period may be associated with wheezing in childhood. OBJECTIVE: This study aimed to investigate the association between early life determinants and wheezing in children aged 6-7 years. MATERIALS AND METHODS: Population-based case-control study using early-life related questions. We used the International Study of Asthma and Allergies in Childhood questionnaire to assess wheezing symptoms. Multiple logistic regressions were performed according to a hierarchical framework, considering the complex dynamic of wheezing/asthma and potential interaction between different levels of determination. RESULTS: A total of 820 children were included, from which 162 reported wheezing symptoms (19.7%). Multivariable analysis identified socioeconomic conditions (OR 2.08, 95% CI 1.08-4.00), family history of asthma (OR 2.28, 95% CI 1.37-3.75), vaginal discharge that required treatment during pregnancy (OR 1.68, 95% CI 1.00-2.83), neonatal hyperbilirubinemia (OR 2.00, 95% CI 1.17-3.42), anemia and intestinal parasitosis in the first two years (OR 2.28, 95% CI 1.22-4.25; OR 1.72, 95% CI 1.02-2.92, respectively) independently associated to wheezing at 6-7 years. Intended pregnancy was associated with reduced wheezing (OR 0.47, 95% CI 0.28-0.77). CONCLUSIONS: Several factors were associated with wheezing in childhood. Considering that intended pregnancy reduced wheezing and other associated exposures are considered modifiable, these findings may guide the planning of strategies to decrease the susceptibility to asthma symptoms in childhood.

Nutritional and non-nutritional habits and occurrence of malocclusions in the mixed dentition.

Malocclusions are changes in the development of craniofacial structures of high prevalence. Associated risk factors are diverse and nutritional and non-nutritional suction habits are the most reported. The aim of this study was to estimate the prevalence of malocclusions in the mixed dentition and to study possible association with practices of breastfeeding and suction habits among Brazilian schoolchildren. A cross-sectional study involving a sample of 664 6-year-old children and their families was carried out. Data collection was done through interviews with mothers in the homes and oral examinations of children in schools. Multivariate analyses were performed using the Poisson regression with a robust estimator. The prevalence of overjet over 4 mm was 21.1% and of posterior crossbite was 12.2%; 91.9% of the children were breastfed, 79.0% used a nursing bottle and 49.4% used a pacifier. Significant and independent associations were observed between father's unemployment, private school, interruption of breastfeeding before the fourth month and pacifier use with certain malocclusions. High rates of malocclusion were found in the studied sample. Socioeconomic conditions, breastfeeding practices and suction habits were shown to be statistically associated with their occurrence.

The burden of AIDS: a time series analysis of thirty-five years of the epidemic in Brazil.

Although traditional epidemiological information, such as mortality rate and prevalence or incidence rates, is relevant to the understanding of AIDS epidemiology in Brazil, a more complete indicator would be recommended. The aim of this study was to estimate the burden of AIDS and its trends in Brazil from 1980 to 2015. An ecological study using secondary data on mortality, morbidity and demography was carried out. Data were collected from official health information sources. Disability-adjusted life years (DALY) index was estimated by year. Trend analysis of the rates were performed using a segmented linear regression method. There were 826,452 confirmed HIV/AIDS cases and 302,614 deaths from AIDS-related causes in the studied period. The greatest burden occurred between 1994 and 1996, with a significant increase in the burden of AIDS for both sexes. The burden of AIDS in Brazil remains high, with a tendency to increase significantly the DALY rates in the study period. However, trend reversals in the DALY rates and in the mortality component, with a consequent increase in the morbidity component, were identified from 1995 onwards.

Methodological description and preliminary results of a cohort study on the influence of the first 1,000 days of life on the children's future health.

The aim of this report is to describe general and methodological characteristics of a cohort study in southern Brazil (Coorte Brasil Sul), aimed at understanding the impact of the first 1,000 days of life on children's health. It is a cohort study involving all children born in 2009 and their families living in the municipality of Palhoça, State of Santa Catarina, Brazil. Face-to-face interviews with parents at home using a structured questionnaire and children's physical and clinical examinations at schools have been carried out. Cross-sectional analyzes, longitudinal comparisons and hierarquical regression analysis will allow understanding if the first 1,000 days of life can influence on 6-year-old children's health. The Coorte Brasil Sul is in its retrospective phase together with the children's physical data collection. Preliminary data (n=1270) related to nutritional status point to a high prevalence of overweight (16.4%) and obesity (15.5%). With the continuity of the study, it is expected to evaluate if the first phases of life can influence health during adolescence and in adult life, mainly in relation to chronic diseases.

Malocclusion in Brazilian Schoolchildren: High Prevalence and Low Impact.

PURPOSE: To estimate the prevalence and severity of malocclusion and test a possible association with negative impacts on quality of life of schoolchildren in Tubarão, Brazil. MATERIALS AND METHODS: A cross-sectional study was conducted on a representative sample (n = 389) of schoolchildren. Data on oral health-related quality of life were obtained through the Oral Impacts on Daily Performance (OIDP) scale. The malocclusion indicator was the Dental Aesthetic Index (DAI). Prevalence ratios were estimated using log-linear Poisson regression with a robust estimator. RESULTS: The prevalence of class II, III, and IV malocclusion was 57.3%. The most common dental condition was overjet greater than 3 mm. Girls and older schoolchildren showed statistically significantly higher prevalence of all classes of malocclusion. There were no statistically significant associations between the most frequent malocclusions and dimensions of the impact indicator, except for the presence of overjet greater than 3 mm that was associated the 'cleaning teeth' dimension. CONCLUSION: The prevalence of malocclusion was high, but was not statistically significantly associated with impact on oral health-related quality of life.

Indicators of violence and asthma: An ecological study.

BACKGROUND: Global studies on asthma point to socioeconomic status as one of the main variables in terms of prevalence and disease severity in various parts of the world. Social factors related to community violence have been linked to higher incidence of asthma in the current studies. This study investigates the relationship between indicators of both community violence and development and hospital admissions due to asthma. METHODS: This was an analytical ecological study of multiple groups, using public databases with information up until 2006. All Brazilian municipalities with more than 100,000 inhabitants were considered as units of analysis. The main index used as socioeconomic indicator was the FIRJAN Index of Municipal Development (FIMD). The Index of Youth Vulnerability to Violence (IYVV) was used as indicators of community violence. The rate of admissions due to asthma was used as the outcome. Pearson's correlation was used for multivariate analyses. The coefficient of determination (R(2)) was calculated and the simple linear regression model adjusted for significant correlations. RESULTS: There was an inverse correlation between asthma admissions and FIMD (r = -0.354, p < 0.001), with statistical significance for all dimensions of the index. Admissions due to asthma were associated with the IYVV (r = 0.240, p < 0.001) and its component related to school attendance and employment (r = 0.315, p < 0.001), homicides (r = 0.112, p = 0.034), and poverty (r = 0.303, p < 0.001). CONCLUSIONS: There was a direct correlation between indicators of violence and rates of admission due asthma, and an inverse correlation with indicators of development. These results suggest that social detriment can act as a risk factor for hospital admissions due to asthma.

Factors associated with hepatitis C seropositivity in people living with HIV.

OBJECTIVE: To identify risk factors associated with hepatitis C virus (HCV) seropositivity in human immunodeficiency virus (HIV)-infected patients. METHODS: A paired case-control study adjusted by age and gender was conducted. It included adults coinfected with HIV and HCV (cases) and HIV mono-infected subjects (controls) using non-probability sampling. Data were collected through interviews and review of medical records. The chi-square test was used for comparing categorical variables and the Student's t-test or Wilcoxon (Mann-Whitney U) test for continuous variables. Confidence intervals (95%) were estimated along with crude and adjusted odds ratios using conditional logistic regression. RESULTS: A total of 165 patients were surveyed, including 55 cases and 110 controls. The mean age was 43.6 ± 8.4 years, ranging from 19 to 64 years; 70.9% were male. Independent risk factors for HIV/HCV coinfection were education (up to eight years of schooling); age at first intercourse < 15 years; having undergone tattooing; blood transfusion; and use of injecting drugs. CONCLUSIONS: Low level of education, early age at first sexual intercourse, tattooing, blood transfusions, and sharing needles and other drug injection equipment were factors that increased the risk of HIV/HCV coinfection. The results from this research can be compared with similar data from other regions to help direct preventive and educational efforts targeting people living with HIV.

Accuracy of neck circumference in the diagnosis of overweight in children.

OBJECTIVE: The objective of this study was to estimate the accuracy of measuring neck circumference as a diagnostic method for overweight in 10-year-old children. METHODS: A cross-sectional diagnostic accuracy study was performed in 2019. The population was composed of 942 school children from the municipality of Palhoça, SC, Brazil. For each measurement of the neck circumference, sensitivity, specificity, positive and negative predictive values, likelihood ratio for a positive test, and accuracy were estimated using the receiver operator characteristic curve, with body mass index as a reference. RESULTS: The estimated overall accuracy was 88.9%. For males, the accuracy was 90.1%, and for females, 88.5%. A 30.0 cm neck circumference had a sensitivity of 22.8%, a specificity of 95.4%, a positive predictive value of 76.6%, a negative predictive value of 65.3%, a likelihood ratio for a positive test of 5.0, and an accuracy of 66.7% for all students. CONCLUSION: Neck circumference showed a global accuracy of 88.9% as a method for diagnosing overweight in 10-year-old children. Predictive values showed high values, mainly starting with a neck circumference of 30 cm.

Quality of life of people living with HIV.

HIV infection is a global growing pandemic, and it is considered a public health problem. Treatment advances improved survival rates for HIV-infected individuals, although not always with a good quality of life (QoL). The aim of this study was to assess the QoL of people living with HIV (PLHIV) in the city of São José, Brazil. A cross-sectional study was performed involving a convenience sample of 85 individuals. Self-administered questionnaires were used to collect sociodemographic information, treatment length and period of infection. The WHOQoL-HIV-Bref instrument was used to assess QoL. The collected data were first described in proportions, means, median and percentiles. Chi-square test or Fisher's exact test was used to test association between the perception of poor QoL taking the first quartile of the distribution of values with gender, age, education level, marital status, period of diagnosis, infection status, self-rated health status and believing to be ill or not. The p values were established at <0.05. The found mean score of WHOQoL-HIV-Bref was 14.1 (SD = 2.9). Lower education level (p=0.011) and believing to be ill (p<0.001) were associated with poor QoL. Also lower education level was associated with poor QoL in the psychological (p=0.020) and environment (p=0.047) domains; being diagnosed with HIV infection within the past five years (p=0.029) was found to be associated with poor QoL in the social relationships domain; and believing to be ill was associated with all domains (physical: p<0.001; psychological: p=0.022; level of independence: p=0.009; social relationships: p=0.009; environment: p=0.005; and spirituality/religion/personal beliefs: p=0.021). It could be concluded that in general, PLHIV have a good QoL. A poor QoL was associated mainly with lower education level and when they believe to be ill.

Dental pain in Brazilian schoolchildren: a cross-sectional study.

AIM: To estimate the prevalence, intensity and associated factors of dental pain in 7- and 8-year-old schoolchildren in a Southern Brazilian city. DESIGN: A cross-sectional study was carried out involving a representative sample (n=401) of schoolchildren of Tubarão, Brazil. The data were obtained through oral examinations, following WHO criteria. Dental pain was analysed using a specific questionnaire developed to measure it. Prevalence and intensity of spontaneous pain and pain caused by cold and hot food and liquids were analysed. Association studies were carried out using chi-square test followed by nonconditional multiple logistic regression analysis to test for independence of association between outcomes and explanatory variables. RESULTS: The prevalence of spontaneous dental pain and dental pain caused by cold and hot food and liquids was 31.7 and 28.1%, respectively. Females and schoolchildren who had visited the dentist at least once showed statistically higher prevalence of spontaneous pain and pain caused by cold and hot food and liquids. Eight-year-old schoolchildren and those presenting cavities in the primary dentition also showed higher prevalence of spontaneous dental pain. CONCLUSIONS: The prevalence and intensity of dental pain were considered high. The prevalence showed to be associated with female gender, higher age, the presence of cavities in the primary dentition and dental visit.

Malocclusion, dental aesthetic self-perception and quality of life in a 18 to 21 year-old population: a cross section study.

BACKGROUND: Aesthetic alterations in the face can be self-perceived and can affect quality of life. For young people, physical attractiveness is an important factor affecting social relationships. The aim of this study was to estimate the prevalence of malocclusion, identify the most common types and test its association with oral aesthetic self-perception in 18 to 21 year-old population of male young adults. METHODS: A cross-sectional study was carried out involving 138 Brazilian Army soldiers. Data collection included socio demographic profile, malocclusion status through the Dental Aesthetic Index (DAI) and oral aesthetic self-perception as indicated by the Oral Aesthetic Subjective Impact Scale (OASIS). The chi-square and Fisher's exact test were used to test for homogeneity of proportions. The stepwise multivariate logistic regression analysis was used to test for the relationship between the poorer oral aesthetic self-perception and parental and soldier's education, per capita income, history of caries in all teeth and only on anterior teeth, dental trauma, previous orthodontic treatment and malocclusion. RESULTS: The prevalence of malocclusion was 45.6%. Incisor teeth crowding and misalignment of lower incisors were the most common types of malocclusions. A statistically significant and independent association between malocclusion and poorer oral aesthetic self-perception in the multivariate analysis was observed. Subjects with severe malocclusion conditions showed 88% higher prevalence [prevalence ratio =1.88 (95% CI, 1.30 - 2.72); p = 0.001] of poorer aesthetic self-perception comparing to those with minor malocclusion. CONCLUSIONS: A high prevalence of malocclusion was observed. The young adults presenting severe malocclusion had a higher and independent prevalence of poorer oral aesthetic self-perception.

Consumption of ultra-processed foods and associated factors in six-year-old children. / Consumo de alimentos ultra processados e fatores associados em crianças de seis anos de idade.

This article aims to estimate the prevalence and weekly frequency of ultra-processed food consumption in six-year-old children and associated factors in a municipality in southern Brazil. Cross-sectional study with 956 children. Data were collected through interviews with mothers in the households. The outcomes were the consumption of candies, chewing gum, lollipops and chocolates; stuffed cookies; artificial juices; and soft drinks using the Índice de Alimentação Escolar (School Feeding Index). The independent variables were gender, type of school, education and maternal occupation, breastfeeding, duration of exclusive breastfeeding and the use of bottle. Bivariate analysis was performed using the chi-square test and the multivariate analysis using Poisson regression. In the multivariate analysis, the weekly prevalence of stuffed cookies consumption was 14% higher in students from public schools and 8% higher in children of mothers with less than eight years of schooling. Artificial juice and soft drink consumption was 7% and 8% higher in public school students respectively and 6% higher in bottle-fed children. Most schoolchildren consumed the ultra-processed foods assessed once or twice a week. Consumption was associated with the independent variables assessed.

O objetivo deste artigo é estimar a prevalência e a frequência semanal de consumo de certos alimentos ultra processados por crianças de seis anos e fatores associados em município do Sul do Brasil. Estudo transversal com 956 crianças. Os dados foram coletados por meio de entrevistas com mães nos domicílios. Os desfechos foram o consumo de balas, chicletes, pirulitos e chocolates; bolachas recheadas; sucos artificiais; e refrigerantes por meio do Índice Alimentação do Escolar. As variáveis independentes foram sexo, tipo de escola, escolaridade e ocupação materna, amamentação, tempo de amamentação exclusiva e utilização de mamadeira. A análise bivariada foi realizada pelo qui-quadrado, e a multivariada por meio da regressão de Poisson. Na análise multivariada, a prevalência semanal do consumo de bolacha recheada foi 14% maior nos alunos de escolas públicas e 8% maior em filhos de mães com escolaridade menor do que oito anos. O consumo de suco artificial foi 7% maior entre alunos de escolas públicas e 6% maior nas crianças que fizeram uso de mamadeira. O consumo de refrigerantes foi 8% maior entre alunos de escolas públicas. A maioria dos escolares consumia os alimentos ultra processados estudados de uma a duas vezes na semana. O consumo mostrou-se associado às variáveis independentes estudadas.

Transcultural adaptation of a scale for exclusive breastfeeding to be used in Brazil.

OBJECTIVE: The aim of this study was to perform a cross-cultural adaptation of the Breastfeeding Self-Efficacy Scale in Exclusive Breastfeeding for use in a Brazilian-Portuguese context. METHODS: The cross-cultural adaptation process involved the translation from original English into Brazilian Portuguese by two qualified and independent translators. Both translations were synthesized into a single version that was back-translated into English. An expert committee was created to assess linguistic equivalences, formulating a pre-final version that was tested on ten nursing women attending a maternity hospital. To assess its psychometric properties, a cross-sectional study was carried out. The population consisted of 99 nursing women from a reference maternity hospital in southern Brazil. The scale's stability and internal consistency were measured through Cronbach's alpha. The Pearson's correlation coefficient and the intraclass correlation coefficient between two applications were assessed to ascertain the Breastfeeding Self-Efficacy Scale in Exclusive Breastfeeding-Br scale's reliability. The construct validity was evaluated through exploratory factorial analysis. RESULTS: The Breastfeeding Self-Efficacy Scale in Exclusive Breastfeeding-Br showed a general Cronbach's alpha of 0.849. The test-retest analysis showed a Pearson's correlation coefficient of 0.483 and intraclass correlation coefficient of 0.645. The exploratory factorial analysis showed two domains among the nine items of the Breastfeeding Self-Efficacy Scale in Exclusive Breastfeeding-Br: the functional domain, including six items, and the cognitive domain, including three items, explaining 59.77% of the variance. CONCLUSION: The Breastfeeding Self-Efficacy Scale in Exclusive Breastfeeding-Br was considered adequate for the cultural context and reliable and valid for Brazilian nursing women.

Cross-cultural adaptation and validation of the Iowa Satisfaction with Anesthesia Scale for use in Brazil: a cross-sectional study.

BACKGROUND: The Iowa Satisfaction with Anesthesia Scale (ISAS) was developed to assess the satisfaction of patients undergoing sedation with monitored anesthesia care. This study aimed to cross-culturally adapt the ISAS instrument and evaluate the acceptability, validity, and reliability of the proposed Brazilian version (ISAS-Br). METHODS: The cross-cultural adaptation process involved translation, synthesis, back-translation, expert committee review, pre-testing, and final review of the ISAS-Br. A cross-sectional study was conducted, involving 127 adult individuals undergoing ambulatory surgeries with moderate/deep sedation. The acceptability, reliability, and construct validity of the scale were assessed. RESULTS: The cross-cultural adaptation process did not require significant changes to the final version of the scale. The ISAS-Br demonstrated excellent acceptability, with a completion rate of 99% and an average completion time of 4.6 minutes. Exploratory factor analysis revealed three factors: emotional well-being, physical comfort, and anxiety relief, with respective composite reliability coefficient values of 0.874, 0.580, and 0.428. The test-retest reliability of the ISAS-Br, measured by the intraclass correlation coefficient, was 0.67 (95% confidence interval [95% CI] 0.42 to 0.83), and the Bland-Altman plot showed satisfactory agreement between the measurements. CONCLUSION: The proposed Brazilian version of the ISAS underwent successful cross-cultural adaptation according to international standards. It demonstrated good acceptability and reliability, regarding the assessment of temporal stability. However, the ISAS-Br exhibited low internal consistency for some factors, indicating that this instrument lacks sensitivity to assess the satisfaction of deeply sedated patients. Further studies are necessary to explore the hypotheses raised based on the knowledge of its psychometric properties.

Prenatal, neonatal and postnatal factors and the developmental defects of dental enamel.

OBJECTIVE: To estimate the prevalence of developmental defects in dental enamel and its possible association with prenatal, neonatal and postnatal conditions in six-year-old schoolchildren in a southern Brazilian municipality. METHODS: A cross-sectional study was conducted involving 655 six-year-old schoolchildren. Sociodemographic and health data were collected through interviews with mothers and children's oral examinations at schools. Multivariate analyses were performed using Poisson regression with robust estimator. RESULTS: The prevalence of developmental defects of enamel was 44.0%. Demarcated opacities were the most prevalent, followed by diffuse opacities. Late pregnancy, maternal schooling less than eight years, female gender and child's white skin color were independently associated with the prevalence of demarcated opacities. CONCLUSIONS: The prevalence of developmental defects in dental enamel was 44.0%. Late pregnancy, maternal schooling less than eight years, female gender and child's white skin color were associated with the prevalences.

The burden of disease due to COVID-19 in Florianópolis, Santa Catarina, Brazil, over a one-year period. / A carga de doença por COVID-19 em Florianópolis, Santa Catarina, Brasil, no período de um ano.

COVID-19 has had a powerful impact on society with high rates of morbidity and mortality. The use of an epidemiological indicator that estimates the burden of a disease by aggregating early mortality and non-fatal cases in a single measure has the potential to assist in the planning of more appropriate actions at different levels of health care. The scope of this article is to estimate the burden of disease due to COVID-19 in Florianópolis/SC from April 2020 through March 2021. An ecological study was carried out with data from notification and deaths by COVID-19 in the period of 12 months. The burden indicator called Disability-Adjusted Life Years (DALY) was used, obtained by adding the Years of Life Lost (YLL) to the Years of healthy life lost due to disability (YLD). A total of 78,907 confirmed COVID-19 cases were included. Of these, 763 died during the period under study. Overall, 4,496.9 DALYs were estimated, namely a rate of 883.8 DALYs per 100,000 inhabitants. In males, there were 2,693.1 DALYs, a rate of 1,098.0 DALYs per 100,000 males. In women, there were 1,803.8 DALYs, a rate of 684.4 DALYs per100,000 women. The age group most affected in both sexes was 60 to 69 years. The burden of COVID-19 was high in the city studied. The highest rates were in females and in the 60-69 age group.

A COVID-19 gerou impacto na sociedade com elevados índices de morbidade e mortalidade. A utilização de indicador epidemiológico que estime a carga de doença, agregando em uma medida a mortalidade precoce e os casos não fatais, tem potencial de auxiliar no planejamento de ações adequadas em diferentes níveis de atenção à saúde. O objetivo deste artigo é estimar a carga de doença por COVID-19 em Florianópolis/SC de abril de 2020 a março de 2021. Foi realizado um estudo ecológico com dados de notificação e óbitos por COVID-19 no período de 12 meses. Utilizou-se o indicador de carga denominado Anos de Vida Perdidos Ajustados por Incapacidade (DALY), obtido pela soma dos Anos de Vida Perdidos (YLL) com os Anos Vividos com Incapacidade (YLD). Foram incluídos 78.907 casos de COVID-19 confirmados. Desses, 763 evoluíram a óbito no período estudado. No total, foram estimados 4.496,6 DALYs, taxa de 883,8 DALYs/100.000 habitantes. No sexo masculino, foram 2.693,1 DALYs, taxa de 1.098,0 DALYs/100.000 homens. Em mulheres, foram 1.803,8 DALYs, taxa de 684,4 DALYs/100.000 mulheres. A faixa etária mais acometida em ambos os sexos foi de 60 a 69 anos. Foi alta a carga de COVID-19 na cidade estudada. As maiores taxas foram encontradas no sexo feminino e na faixa-etária de 60-69 anos.