Detalhe da pesquisa
1.
Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy.
Molecules
; 29(9)2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731613
2.
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration.
J Virol
; 96(14): e0067622, 2022 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758669
3.
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach.
J Chem Inf Model
; 63(11): 3601-3613, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37227780
4.
Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds.
Bioorg Med Chem
; 90: 117376, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37336083
5.
Unlocking STING as a Therapeutic Antiviral Strategy.
Int J Mol Sci
; 24(8)2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108610
6.
Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity.
Molecules
; 28(18)2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764476
7.
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach.
Molecules
; 27(21)2022 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36364347
8.
Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships.
Retrovirology
; 18(1): 34, 2021 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34715873
9.
RNA-Seq Transcriptome Analysis Reveals Long Terminal Repeat Retrotransposon Modulation in Human Peripheral Blood Mononuclear Cells after In Vivo Lipopolysaccharide Injection.
J Virol
; 94(19)2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669333
10.
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function.
J Enzyme Inhib Med Chem
; 36(1): 749-757, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33715562
11.
Garcinol from Garcinia indica inhibits HIV-1 reverse transcriptase-associated ribonuclease H.
Arch Pharm (Weinheim)
; 354(9): e2100123, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34008218
12.
Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L.
Int J Mol Sci
; 22(21)2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769210
13.
Natural and Nature-Derived Products Targeting Human Coronaviruses.
Molecules
; 26(2)2021 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33467029
14.
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata.
Molecules
; 26(16)2021 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34443358
15.
Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions.
Molecules
; 26(13)2021 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34201561
16.
Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366711
17.
Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome.
J Virol
; 93(16)2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31167914
18.
Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H.
J Enzyme Inhib Med Chem
; 35(1): 1953-1963, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33143469
19.
Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923.
Int J Mol Sci
; 21(16)2020 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781637
20.
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication.
Molecules
; 25(6)2020 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183488