Detalhe da pesquisa
1.
The voltage-gated sodium channel NaV 1.7 underlies endometriosis-associated chronic pelvic pain.
J Neurochem
; 2023 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840383
2.
Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific.
Bioconjug Chem
; 34(6): 1072-1083, 2023 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37262436
3.
GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms.
Epilepsia
; 64(12): 3377-3388, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734923
4.
Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.
J Biol Chem
; 295(15): 5067-5080, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139508
5.
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides.
Bioconjug Chem
; 32(11): 2407-2419, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34751572
6.
Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel NaV1.7 Inhibition.
Bioconjug Chem
; 31(1): 64-73, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790574
7.
Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH.
ACS Omega
; 8(29): 26276-26286, 2023 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37521635
8.
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Nat Commun
; 14(1): 2442, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37117223
9.
Enzymatic Ligation of Disulfide-Rich Animal Venom Peptides: Using Sortase A to Form Double-Knotted Peptides.
Methods Mol Biol
; 2355: 83-92, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34386952
10.
The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation.
Front Pharmacol
; 12: 789570, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35095499