Pesquisa | BVS Violência e Saúde

1.

Charting human development using a multi-endodermal organ atlas and organoid models.

Yu, Qianhui; Kilik, Umut; Holloway, Emily M; Tsai, Yu-Hwai; Harmel, Christoph; Wu, Angeline; Wu, Joshua H; Czerwinski, Michael; Childs, Charlie J; He, Zhisong; Capeling, Meghan M; Huang, Sha; Glass, Ian A; Higgins, Peter D R; Treutlein, Barbara; Spence, Jason R; Camp, J Gray.

Cell ; 184(12): 3281-3298.e22, 2021 06 10.

Artigo em Inglês | MEDLINE | ID: mdl-34019796

2.

Inferring and perturbing cell fate regulomes in human brain organoids.

Fleck, Jonas Simon; Jansen, Sophie Martina Johanna; Wollny, Damian; Zenk, Fides; Seimiya, Makiko; Jain, Akanksha; Okamoto, Ryoko; Santel, Malgorzata; He, Zhisong; Camp, J Gray; Treutlein, Barbara.

Nature ; 621(7978): 365-372, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-36198796

3.

Single-cell brain organoid screening identifies developmental defects in autism.

Li, Chong; Fleck, Jonas Simon; Martins-Costa, Catarina; Burkard, Thomas R; Themann, Jan; Stuempflen, Marlene; Peer, Angela Maria; Vertesy, Ábel; Littleboy, Jamie B; Esk, Christopher; Elling, Ulrich; Kasprian, Gregor; Corsini, Nina S; Treutlein, Barbara; Knoblich, Juergen A.

Nature ; 621(7978): 373-380, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37704762

4.

A nomenclature consensus for nervous system organoids and assembloids.

PaÈca, Sergiu P; Arlotta, Paola; Bateup, Helen S; Camp, J Gray; Cappello, Silvia; Gage, Fred H; Knoblich, Jürgen A; Kriegstein, Arnold R; Lancaster, Madeline A; Ming, Guo-Li; Muotri, Alysson R; Park, In-Hyun; Reiner, Orly; Song, Hongjun; Studer, Lorenz; Temple, Sally; Testa, Giuseppe; Treutlein, Barbara; Vaccarino, Flora M.

Nature ; 609(7929): 907-910, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36171373

5.

A roadmap for the Human Developmental Cell Atlas.

Haniffa, Muzlifah; Taylor, Deanne; Linnarsson, Sten; Aronow, Bruce J; Bader, Gary D; Barker, Roger A; Camara, Pablo G; Camp, J Gray; Chédotal, Alain; Copp, Andrew; Etchevers, Heather C; Giacobini, Paolo; Göttgens, Berthold; Guo, Guoji; Hupalowska, Ania; James, Kylie R; Kirby, Emily; Kriegstein, Arnold; Lundeberg, Joakim; Marioni, John C; Meyer, Kerstin B; Niakan, Kathy K; Nilsson, Mats; Olabi, Bayanne; Pe'er, Dana; Regev, Aviv; Rood, Jennifer; Rozenblatt-Rosen, Orit; Satija, Rahul; Teichmann, Sarah A; Treutlein, Barbara; Vento-Tormo, Roser; Webb, Simone.

Nature ; 597(7875): 196-205, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34497388

6.

The road ahead in genetics and genomics.

McGuire, Amy L; Gabriel, Stacey; Tishkoff, Sarah A; Wonkam, Ambroise; Chakravarti, Aravinda; Furlong, Eileen E M; Treutlein, Barbara; Meissner, Alexander; Chang, Howard Y; López-Bigas, Núria; Segal, Eran; Kim, Jin-Soo.

Nat Rev Genet ; 21(10): 581-596, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32839576

7.

Lineage recording in human cerebral organoids.

He, Zhisong; Maynard, Ashley; Jain, Akanksha; Gerber, Tobias; Petri, Rebecca; Lin, Hsiu-Chuan; Santel, Malgorzata; Ly, Kevin; Dupré, Jean-Samuel; Sidow, Leila; Sanchis Calleja, Fatima; Jansen, Sophie M J; Riesenberg, Stephan; Camp, J Gray; Treutlein, Barbara.

Nat Methods ; 19(1): 90-99, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34969984

8.

Organoid single-cell genomic atlas uncovers human-specific features of brain development.

Kanton, Sabina; Boyle, Michael James; He, Zhisong; Santel, Malgorzata; Weigert, Anne; Sanchís-Calleja, Fátima; Guijarro, Patricia; Sidow, Leila; Fleck, Jonas Simon; Han, Dingding; Qian, Zhengzong; Heide, Michael; Huttner, Wieland B; Khaitovich, Philipp; Pääbo, Svante; Treutlein, Barbara; Camp, J Gray.

Nature ; 574(7778): 418-422, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31619793

9.

Author Correction: Single-cell brain organoid screening identifies developmental defects in autism.

Li, Chong; Fleck, Jonas Simon; Martins-Costa, Catarina; Burkard, Thomas R; Themann, Jan; Stuempflen, Marlene; Peer, Angela Maria; Vertesy, Ábel; Littleboy, Jamie B; Esk, Christopher; Elling, Ulrich; Kasprian, Gregor; Corsini, Nina S; Treutlein, Barbara; Knoblich, Juergen A.

Nature ; 623(7989): E20, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37964131

10.

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains.

Khrameeva, Ekaterina; Kurochkin, Ilia; Han, Dingding; Guijarro, Patricia; Kanton, Sabina; Santel, Malgorzata; Qian, Zhengzong; Rong, Shen; Mazin, Pavel; Sabirov, Marat; Bulat, Matvei; Efimova, Olga; Tkachev, Anna; Guo, Song; Sherwood, Chet C; Camp, J Gray; Pääbo, Svante; Treutlein, Barbara; Khaitovich, Philipp.

Genome Res ; 30(5): 776-789, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-32424074

11.

Human brain organoids influence rat behaviour.

Camp, J Gray; Treutlein, Barbara.

Nature ; 610(7931): 265-266, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36224409

12.

Multilineage communication regulates human liver bud development from pluripotency.

Camp, J Gray; Sekine, Keisuke; Gerber, Tobias; Loeffler-Wirth, Henry; Binder, Hans; Gac, Malgorzata; Kanton, Sabina; Kageyama, Jorge; Damm, Georg; Seehofer, Daniel; Belicova, Lenka; Bickle, Marc; Barsacchi, Rico; Okuda, Ryo; Yoshizawa, Emi; Kimura, Masaki; Ayabe, Hiroaki; Taniguchi, Hideki; Takebe, Takanori; Treutlein, Barbara.

Nature ; 546(7659): 533-538, 2017 06 22.

Artigo em Inglês | MEDLINE | ID: mdl-28614297

13.

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq.

Treutlein, Barbara; Lee, Qian Yi; Camp, J Gray; Mall, Moritz; Koh, Winston; Shariati, Seyed Ali Mohammad; Sim, Sopheak; Neff, Norma F; Skotheim, Jan M; Wernig, Marius; Quake, Stephen R.

Nature ; 534(7607): 391-5, 2016 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-27281220

14.

A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex.

Vaid, Samir; Camp, J Gray; Hersemann, Lena; Eugster Oegema, Christina; Heninger, Anne-Kristin; Winkler, Sylke; Brandl, Holger; Sarov, Mihail; Treutlein, Barbara; Huttner, Wieland B; Namba, Takashi.

Development ; 145(20)2018 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-30266827

15.

Single-cell genomics to guide human stem cell and tissue engineering.

Camp, J Gray; Wollny, Damian; Treutlein, Barbara.

Nat Methods ; 15(9): 661-667, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-30171231

16.

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.

Vaughan, Andrew E; Brumwell, Alexis N; Xi, Ying; Gotts, Jeffrey E; Brownfield, Doug G; Treutlein, Barbara; Tan, Kevin; Tan, Victor; Liu, Feng Chun; Looney, Mark R; Matthay, Michael A; Rock, Jason R; Chapman, Harold A.

Nature ; 517(7536): 621-5, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25533958

17.

Reconstructing complex lineage trees from scRNA-seq data using MERLoT.

Parra, R Gonzalo; Papadopoulos, Nikolaos; Ahumada-Arranz, Laura; Kholtei, Jakob El; Mottelson, Noah; Horokhovsky, Yehor; Treutlein, Barbara; Soeding, Johannes.

Nucleic Acids Res ; 47(17): 8961-8974, 2019 09 26.

Artigo em Inglês | MEDLINE | ID: mdl-31428793

18.

Human organomics: a fresh approach to understanding human development using single-cell transcriptomics.

Camp, J Gray; Treutlein, Barbara.

Development ; 144(9): 1584-1587, 2017 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-28465333

19.

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq.

Treutlein, Barbara; Brownfield, Doug G; Wu, Angela R; Neff, Norma F; Mantalas, Gary L; Espinoza, F Hernan; Desai, Tushar J; Krasnow, Mark A; Quake, Stephen R.

Nature ; 509(7500): 371-5, 2014 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-24739965

20.

Dynamic architecture of a minimal RNA polymerase II open promoter complex.

Treutlein, Barbara; Muschielok, Adam; Andrecka, Joanna; Jawhari, Anass; Buchen, Claudia; Kostrewa, Dirk; Hög, Friederike; Cramer, Patrick; Michaelis, Jens.

Mol Cell ; 46(2): 136-46, 2012 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-22424775

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